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Cetuximab Radiation Therapy for T1/N1
My mother is diagnosed with T1/N1 carcinoma in the Buccal Mucosa and N1 to a nearby lymph node in the throat.
She underwent surgery and margins of good tissue around the primary tumor was 3mm-5mm, as per the histopathology report.
The lymph node showed extracapsular extension in the histopathology report. Owing to CIN (nephritis), Cisplatin is ruled out.
We wanted to know if Cetuximab should be considered with RT or is only RT sufficient for this stage? We planned for RT in the coming week.
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Concurrent chemo should be offered according to histopath.
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Cetuximab, can be tried else their are other radiosensitizing agents as well
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She would have merited concurrent chemoradiation, but given the background of CIN, your treating doctor should take a call on whether to give radiation alone.
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Additional therapy like cisplatin,cetuximab will be more beneficial when comparex to RT alone.Cetuximab is acceptable regime in your mother condition.
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dicuss with treating oncologist for further discussion on planned treatment.
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Dr. D.Shiva Prasad
Radiation Oncologist
7 yrs exp
Hyderabad
She definitely needs CONCURRENT chemotherapy.. regarding cetuximab, it should be used as the last option only if carboplatin cannot be used...
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Disclaimer : The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding your medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.