TB MEDICINE STARED AND STOPPED REPLACED.

My son aged 20 years. Detected with Lymph node TB, 45 days ago. Then Doctor started Anti-TB Medicine (AKT4) continued for 27 days. Then treating doctor STOPPED 3 out of 4 drugs (due to High AST and ALT level) and only Ethambutol=1200 with addition of Livofloxacine 750 continuing till today. It is continuing for last 15 days. But Fever continuing last 39 days irrespective of AKT4 and change of medicine thereafter. Gene Xpert Report- DETECTED Mycrobacterium Tuberculosis , and NO Refampicin RESISTANCY. His SGPT & SGOT LEVELS are changing as follow: BEFORE SGPT SGOT DAYS ALT AST 26 125 184 17 302 285 (AKT-4-4 STOPPED after this) 10 190 135 3 161 135 My questions: 1) In which level should AST & ALT to come down to SATRT AKT-4 again? -2) After STOPPING of AKT-4 and replacing it with Ethambutol=1200 + Livofloxacine 750 (for 21 days or more) ::- a) Can new medicines control TB to spread Further to Brainor other vital organs?