As noted, in my experience, in most instances, the cause of the elevated IgE in patients with late onset (intrinsic) asthma remains undetected.  I have seen several patients in the last several years with highly elevated IgE levels with negative inhalant and select food allergy skin tests and RAST. In Allopathy, anti-histaminics or immunosuppressant medicines like steroids are used which only give temporary relief, with the problem returning once the medicine is stopped. On the other hand, during Homeopathy treatment of allergy is cured by strengthening the immune system and the symptoms subside on their own. At the same time, it needs to be understood that this is purely natural allergy treatment. No steroids or anti allergic medicines are used. The immunity is strengthened by Homeopathy instead of being suppressed as happens with allopathic treatment. You can easily take an online consultation for further treatment guidance.