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Amitone 10 MG Tablet
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Amitone 10 MG Tablet

Manufactured byIntas Pharmaceuticals Ltd.
ContainsAmitriptyline
Description
Amitone 10 MG Tablet is an antidepressant medicine. It is used in the treatment of depression and other conditions such as nerve pain and migraine. It works by increasing the levels of chemical substances in your brain and improving your mood. It also blocks the transmission of pain signals and provides relief from nerve pain. Amitone 10 MG Tablet may cause common side effects such as dizziness, sleepiness, dryness in the mouth, weight gain, nasal congestion, etc. Consult your doctor if these symptoms stay for a long time or if they become severe. Amitone 10 MG Tablet should be taken exactly as advised by your doctor. Take it at the same time every day. Do not skip doses or discontinue the treatment without consulting your doctor as it may cause withdrawal symptoms such as fatigue, sleep disturbances, irritability, etc. To avoid these, gradual dose reduction is necessary under your doctor’s supervision. Amitone 10 MG Tablet should be avoided if you are allergic to it or have heart problems. Inform your doctor if you have liver problems, diabetes, or a history of seizures (a condition that occurs due to abnormal brain activity causing fits) or glaucoma (an eye condition that occurs due to increased pressure within the eyeballs) before taking this medicine. Inform your doctor about your current medicines to avoid any undesired effects. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Amitone 10 MG Tablet

Amit 10 MG Tablet
Orchid Chemicals & Pharmaceuticals Ltd.
Amitor 10 MG Tablet
Torrent Pharmaceuticals Ltd.
Eliwel 10 MG Tablet
Sun Pharma Laboratories Ltd.
Tadamit 10 MG Tablet
Alkem Laboratories Ltd.
Triptova 10 MG Tablet
Alkem Laboratories Ltd.

Side effects

Major & minor side effects for Amitone 10 MG Tablet

  • Drowsiness or sleepiness
  • Shakiness
  • Dizziness
  • Dizziness when getting up suddenly from a sitting position
  • Headache
  • Dry mouth
  • Constipation
  • Excessive sweating
  • Weight gain
  • Slow or slurred speech
  • Nasal congestion
  • Confusion
  • Decrease in sexual drive
  • Increased thirst
  • Difficulty in passing urine

Uses of Amitone 10 MG Tablet

What is it prescribed for?

  • Depression
  • Neuropathic pain
  • Migraine
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Amitone 10 MG Tablet has a slow onset of action and may take 4 to 6 weeks to show its effects.
  • How long do the effects of this medicine last?
    Amitone 10 MG Tablet may remain in your body for approximately 5 days.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Amitone 10 MG Tablet as it may increase the risk of side effects such as drowsiness, confusion, blurred vision, sweating, muscle stiffness, light-headedness, etc. Avoid performing activities that require mental alertness such as driving and/or operating machines if you experience these symptoms.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported with Amitone 10 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Amitone 10 MG Tablet is not recommended for use during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Amitone 10 MG Tablet passes into breastmilk and may cause side effects in your baby. This medicine is not recommended for use if you are breastfeeding.

Allergy

Avoid taking Amitone 10 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Monoamine oxidase inhibitors

Monoamine oxidase inhibitors (MAOI) are a class of medicines used to treat depression. Amitone 10 MG Tablet is not recommended for use if you have taken MAOIs within the last 14 days due to the increased risk of serious side effects.

Heart Attack

Amitone 10 MG Tablet is not recommended for use if you recently had a heart attack as it may further worsen your condition.

Severe liver impairment

Amitone 10 MG Tablet is not recommended for use if you have severe liver problems as it may cause further liver damage.
Warnings for special population

Pregnancy

Amitone 10 MG Tablet is not recommended for use during pregnancy as it may harm your foetus. Consult your doctor if you are pregnant.

Breast-feeding

Amitone 10 MG Tablet passes into breastmilk and may cause side effects in your baby. This medicine is not recommended for use if you are breastfeeding.
General warnings

Driving or operating machines

Amitone 10 MG Tablet may increase your risk of dizziness and sleepiness. Avoid driving or operating machines if you experience these symptoms.

Hypotension (Low blood pressure)

A high dose of Amitone 10 MG Tablet should be used with caution as it may increase your risk of low blood pressure. It is recommended that you regularly monitor your blood pressure while taking this medicine.

Suicidal tendencies

Amitone 10 MG Tablet should be used with caution due to the increased risk of suicidal thoughts. Closely monitor for any change in behaviour or mood while taking this medicine. Consult your doctor immediately if you experience any change in behaviour or suicidal thoughts.

Use in children

Amitone 10 MG Tablet is not recommended for use in children below 18 years of age for the treatment of depression, neuropathic pain, and migraine due to lack of safety and efficacy data.

Elderly

Amitone 10 MG Tablet should be used with caution in elderly people due to the increased risk of side effects. Appropriate dose adjustments may be necessary based on the clinical condition.

Withdrawal symptoms

Amitone 10 MG Tablet should not be discontinued suddenly as it may result in withdrawal symptoms such as headache, weakness, fatigue, sleep disturbances, irritability. etc. Gradual dose reduction should be done over a period under your doctor's supervision.

Missed Dose

Try not to skip a dose of Amitone 10 MG Tablet. Take the missed dose as soon as you remember. If it is time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Do not take more than the prescribed dose. Contact your doctor if you suspect an overdose with Amitone 10 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Amitone 10 MG Tablet as it may increase the risk of side effects such as drowsiness, confusion, blurred vision, sweating, muscle stiffness, light-headedness, etc. Avoid performing activities that require mental alertness such as driving and/or operating machines if you experience these symptoms.
Interaction with Medicine

Fluoxetine

Topiramate

Duloxetine

Warfarin

Diphenhydramine

Zolpidem

Azithromycin

Hydroxychloroquine

Ondansetron

Moxifloxacin

Disease interactions

Heart Disease

Amitone 10 MG Tablet may cause orthostatic hypotension (a sudden drop in blood pressure when standing up from a sitting/lying down position), irregular heartbeats, QT prolongation (a condition in which your heart muscles take a longer time to recharge between a heartbeat), heart attack or stroke (a decrease in blood supply to your brain). Hence, this medicine should be used with caution if you have heart problems. Consult your doctor before starting the treatment with this medicine.

Phaeochromocytoma

Phaeochromocytoma is a rare tumour of the adrenal glands (a small gland located on top of your kidney that is responsible for producing chemical substances known as hormones). Amitone 10 MG Tablet should be used with caution if you have phaeochromocytoma as it may further worsen your condition.

Seizures

Seizure is a condition that occurs due to disturbed nerve cell activity in your brain resulting in abnormal behaviour and loss of consciousness. Amitone 10 MG Tablet should be used with caution if you have a history of seizures as this medicine may trigger seizures.

Bone marrow suppression

Bone marrow suppression is a condition in which there is decreased production of blood cells in your bone marrow (a spongy substance present at the centre of your bones). Amitone 10 MG Tablet should be used with caution if you have bone marrow suppression as it may cause a further decrease in blood counts.

Diabetes

Amitone 10 MG Tablet should be used with caution if you have diabetes (high blood sugar levels) due to the increased risk of altered blood sugar levels. Regularly monitor your blood sugar levels while taking this medicine.

Tardive Dyskinesia

Tardive dyskinesia is a neurological condition with repetitive, involuntary body movements. Amitone 10 MG Tablet should be used with caution if you have tardive dyskinesia as it may further worsen your condition.

Glaucoma

Glaucoma is a condition in which the optic nerve (the nerve connecting the eye to the brain) is damaged, usually due to high pressure within your eyeballs. Amitone 10 MG Tablet should be used with caution if you have a history of glaucoma as this medicine may increase the pressure within your eyeballs. Your doctor may periodically monitor your intraocular pressure (pressure inside the eye) during treatment with this medicine.

Liver Disease

Amitone 10 MG Tablet is broken down in your liver. Hence, this medicine should be used with caution if you have pre-existing liver problems due to the increased risk of severe side effects. It may also cause further liver damage. Your doctor may suggest tests to periodically monitor your liver function and liver enzyme levels while you are taking this medicine.

Kidney Disease

Amitone 10 MG Tablet should be used with caution if you have pre-existing kidney problems due to the increased risk of severe side effects. Your kidney function should be periodically monitored while you are on treatment with this medicine.

Urinary retention

Urinary retention is a condition in which you cannot empty your bladder completely when you urinate. Amitone 10 MG Tablet should be used with caution if you have such a condition as this medicine may increase your risk of urinary retention.

Hyperthyroidism

Hyperthyroidism is a condition that occurs due to high levels of thyroid hormone in your body. Amitone 10 MG Tablet should be used with caution if you have hyperthyroidism due to the increased risk of developing an irregular heartbeat.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Amitone 10 MG Tablet with or without food. Do not take more or less than the prescribed dose. Avoid the discontinuation of Amitone 10 MG Tablet without consulting your doctor as it may result in withdrawal symptoms. Amitone 10 MG Tablet may increase your risk of suicidal thoughts. Consult your doctor if you experience any changes in mood or behaviour. Avoid consuming alcohol while taking Amitone 10 MG Tablet as it may cause drowsiness and dizziness. Avoid driving or operating machines if you experience symptoms that may affect your mental alertness.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Amitone 10 MG Tablet works by increasing the levels of chemical substances in your brain (norepinephrine and serotonin). Thus, it helps to improve your mood. It also prevents the pain signals from being sent from nerves to the brain, thus provides relief from nerve pain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Tricyclic antidepressants

Schedule

Schedule H

Medicines.org.uk. 2021. [online] Available at: < [Accessed 9 September 2021].

https://www.medicines.org.uk/emc/files/pil.5698.pdf>

Medicines.org.uk. 2021. Amitriptyline 10mg Tablets BP - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 9 September 2021].

https://www.medicines.org.uk/emc/product/5698/smpc>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 9 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/085966s095,085969s084,085968s096,085971s075,085967s076,085970s072lbl.pdf>
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Information on this page was last updated on 28 Sep 2021

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