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Huminsulin U 40 IU Injection

Manufactured byEli Lilly And Company (India) Pvt. Ltd.
ContainsInsulin - Neutral Protaminated Hagedorn (NPH)
CURRENTLY UNAVAILABLE

Description

Huminsulin U 40 IU Injection is used in the treatment of diabetes mellitus. Insulin is a natural substance produced by the body which helps in utilizing the glucose for energy production. The patients with diabetes mellitus may not be able to utilize glucose due to the insufficient production of insulin or due to the body's inability to use the insulin produced or both. This medicine helps in the utilization of glucose and controlling blood glucose levels in such patients. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect.
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Substitutes

List of substitutes for Huminsulin U 40 IU Injection

Human Insulong 40 IU Injection
Glenmark Pharmaceuticals Ltd.
Humanext-N 40 IU Injection
Cadila Pharmaceuticals Ltd.
Huminsulin N 40 IU Injection
Eli Lilly And Company (India) Pvt. Ltd.
Insulin (NND) 40 IU Injection
Novo Nordisk India Pvt. Ltd.
Lentard 40 IU Injection
Novo Nordisk India Pvt. Ltd.

Side effects

Major & minor side effects for Huminsulin U 40 IU Injection

Hypersensitivity

Burning, numbness, tingling in the arms and feet

Changes in vision

Diabetic retinopathy

Lipodystrophy

Hypoglycemia

Irregular heartbeat

Edema

Injection site pain

Uses of Huminsulin U 40 IU Injection

What is it prescribed for?

Type 1 Diabetes mellitus

This medicine is used in the treatment of Type 1 Diabetes mellitus, a lifelong condition in which the pancreas does not produce sufficient insulin to control the blood sugar level.

Type II Diabetes Mellitus

This medicine is used in the treatment of Type II Diabetes Mellitus, a lifelong condition in which the insulin produced by the body cannot be used properly by the cells to convert the glucose into energy.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of this medicine can be observed within 1 to 3 hours of administration of the dose.

  • How long do the effects of this medicine last?

    The effect of this medicine lasts for an average duration of 14 to 24 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of both hypoglycemia and hyperglycemia depending on the quantity and frequency of alcohol consumption. This may cause severe side effects such as dizziness, drowsiness, increased thirst, increased hunger, mood changes, extreme fatigue, etc.

  • Is this a habit forming medicine?

    No habit forming tendencies were reported.

  • Can this medicine be taken during pregnancy?

    This medicine is considered safe for use by pregnant women. However, it must be used only when necessary and the potential benefits outweigh the risks.

  • Can this medicine be taken while breast-feeding?

    Use of insulin by breastfeeding women is considered acceptable. Breastfeeding women generally require lower doses of insulin.

Allergy

This medicine is not recommended for use if you have a known allergy to Neutral Protamine Hagedorn insulin or any other components present along with it.

Hypoglycemia

This medicine is not recommended for use if you have a low blood sugar level (hypoglycemia).

Warnings for special population

Pregnancy

This medicine is considered safe for use by pregnant women. However, it must be used only when necessary and the potential benefits outweigh the risks.

Breast-feeding

Use of insulin by breastfeeding women is considered acceptable. Breastfeeding women generally require lower doses of insulin.

General warnings

Route of administration

This medicine should be administered through the subcutaneous route only.

Single person use

This medicine should not be shared with others.

Nature of the injection solution

This medicine should appear cloudy or milky. Do not use the medicine if it appears clear upon shaking.

Travel to a different time zone

It is recommended to get proper instructions about the insulin injection timings and diet-related information from the doctor before traveling to a different time zone.

Changing the type and brand of insulin

Transferring to a different brand or type of insulin should be done under strict medical supervision.

Drowsiness

This medicine may cause hypoglycemia. Symptoms of hypoglycemia include drowsiness, impaired judgment, and difficulty with concentration. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery immediately after administering this medicine.

Use in infusion pumps

Huminsulin U 40 IU Injection is not recommended for use in insulin infusion pumps.

Missed Dose

Administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek immediate medical attention or contact the doctor if an overdose of this medicine is suspected. Hypoglycemia may occur in sequential stages if too high doses of Huminsulin U 40 IU Injection are administered. For mild hypoglycemic episodes, oral glucose or sugary products can be used to avoid severe hypoglycemia. If there is severe hypoglycemia, IM or SC glucagon or IV glucose needs to be administered by a trained healthcare professional. If there is no response to glucagon within 10 to 15 minutes, IV glucose is administered. It is recommended to give oral carbohydrates to avoid the relapse of hypoglycemic episodes when consciousness is regained.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of both hypoglycemia and hyperglycemia depending on the quantity and frequency of alcohol consumption. This may cause severe side effects such as dizziness, drowsiness, increased thirst, increased hunger, mood changes, extreme fatigue, etc.

Interaction with Medicine

Ciprofloxacin

Dopamine

Clonidine

Acetazolamide

Gatifloxacin

Acebutolol

Dapagliflozin

Disease interactions

Renal Diseases

The requirement of insulin may be reduced in patients with renal impairment. Blood glucose levels should be monitored closely and the treatment should be initiated at lower doses for such patients.

Hypokalemia

Caution is advised if this medicine is used in patients at increased risk of developing hypokalemia since it may worsen the patient's condition. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

The requirement of insulin may be reduced in patients with hepatic impairment. Blood glucose levels should be monitored closely and the treatment should be initiated at lower doses for such patients.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Carefully follow all the instructions given by your doctor. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Do not stop the use of this medicine without consulting your doctor. Close monitoring of blood glucose levels and frequent follow-up visits with the doctor may be required based on the clinical condition.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works

Huminsulin U 40 IU Injection is a replacement insulin which works by enhancing the glucose uptake for energy production. This helps in controlling the blood glucose levels.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Insulin, Antidiabetic agents

Schedule

Schedule G

DailyMed - NOVOLIN N- human insulin injection, suspension [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 12 September 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=82f1445c-b2c6-445a-82cf-ba8825fac776

Insulin N, Holleman F. NPH insulin - Management - Diapedia, The Living Textbook of Diabetes [Internet]. Diapedia.org. 2017 [cited 12 September 2017]. Available from:

https://www.diapedia.org/management/81040961122/nph-insulin

[Internet]. 2017 [cited 12 September 2017]. Available from:

http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/000441/WC500033307.pdf

Calculating Insulin Dose :: Diabetes Education Online [Internet]. Dtc.ucsf.edu. 2017 [cited 12 September 2017]. Available from:

https://dtc.ucsf.edu/types-of-diabetes/type1/treatment-of-type-1-diabetes/medications-and-therapies/type-1-insulin-therapy/calculating-insulin-dose/

[Internet]. 2017 [cited 12 September 2017]. Available from:

http://www.pharmaline.co.il/images/newsletterregistration/novonordisk/12102011/insulatardpenfilldr.pdf

Isophane insulin NPH [Internet]. Snomedbrowser.com. 2017 [cited 12 September 2017]. Available from:

https://snomedbrowser.com/Codes/Details/412221009

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Information on this page was last updated on 15 Sep 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.