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Description
Nizonide 500 Tablet contains Nitazoxanide that is used orally for the treatment of diarrhoea caused by parasites/protozoa. Parasites are the micro-organisms that live in other's bodies and use their body's nutrients to reproduce. This medicine interferes with their energy production and effectively kills the parasites (Giardia and Cryptosporidium species).
Nizonide 500 Tablet may cause nausea, vomiting, headache, urine discolouration and stomach pain. Usually, these side effects are self-resolving, but consult your doctor if any of these side effects persist or worsen. Avoid taking this medicine if you are allergic to it and discontinue if you experience any allergic reaction (skin rash, swelling of face, lips, tongue, etc.).
Nizonide 500 Tablet may make you feel dizzy and sleepy. Avoid driving or operating a machine if you feel dizzy or sleepy after taking this medicine. Avoid alcohol consumption while you are on Nizonide 500 Tablet treatment as it can aggravate dizziness.
Take Nizonide 500 Tablet with food to provide better absorption and avoid an upset stomach. Your doctor will decide the dose and duration of this medicine based on the severity of the infection. Ensure to complete the course and avoid doubling the dose in case a dose is missed. Stopping it early may increase your risk of further infection.
To make sure Nizonide 500 Tablet is safe for you, share your entire medical and medication history with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding. This information is critical as it can help your doctor to plan the overall treatment and make dose adjustments if required.
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Substitutes
List of substitutes for Nizonide 500 Tablet
Side effects
Major & minor side effects for Nizonide 500 Tablet
Stomach pain
Nausea and vomiting
Headache
Dizziness
Urine discoloration
Skin rash and itching
Uses of Nizonide 500 Tablet
What is it prescribed for?
Diarrhoea
Diarrhoea is characterized by abnormally loose or watery stools more than 3 times a day. Protozoa are suspected as the cause when diarrhoea lasts for more than 7 days. Nizonide 500 Tablet is used to kill these micro-organisms and thus treats diarrhoea.
Concerns
Commonly asked questions
How long does it take for this medicine to take effect?
Nizonide 500 Tablet start showing its effect in 1-2 hours after taking it orally. However, it may take few days to make you feel better.How long do the effects of this medicine last?
The amount of time for which Nizonide 500 Tablet remains active in the body is not known.Is it safe to consume alcohol while taking this medicine?
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.Is this a habit forming medicine?
Nizonide 500 Tablet has no habit-forming tendency.Can this medicine be taken during pregnancy?
Nizonide 500 Tablet should not be used only after consulting your doctor if you are pregnant.Can this medicine be taken while breast-feeding?
It is not known whether Nizonide 500 Tablet passes into breast milk or not. Your doctor may advise you to discontinue breastfeeding while taking this medicine to ensure the safety of the infant.
Allergy
Avoid taking Nizonide 500 Tablet if you are allergic to it. Seek an immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.
Warnings for special population
Pregnancy
Nizonide 500 Tablet should not be used only after consulting your doctor if you are pregnant.
Breast-feeding
It is not known whether Nizonide 500 Tablet passes into breast milk or not. Your doctor may advise you to discontinue breastfeeding while taking this medicine to ensure the safety of the infant.
General warnings
Liver impairment
Nizonide 500 Tablet gets converted into its active form in your liver. An impaired liver cannot convert this medicine properly and accumulation of this medicine takes place in your liver. This accumulation may worsen your liver condition.
Kidney impairment
Nizonide 500 Tablet is excreted by kidneys. An impaired kidney cannot filter out this medicine properly and accumulation of this medicine takes place in kidneys. This accumulation can worsen your kidney condition.
Use in children
Nizonide 500 Tablet is not recommended for use in children below 1-year of age because the safety and efficacy have not been clinically established.
Missed Dose
If you have missed Nizonide 500 Tablet dose, make sure that you remember to take the next dose on time. Do not take two doses together to make up for a forgotten dose.
Overdose
Never take Nizonide 500 Tablet more than the prescribed dose. If you suspect that you have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Valproic Acid
Lorazepam
Phenytoin
Warfarin
Disease interactions
Disease
Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Nizonide 500 Tablet with food to avoid an upset stomach.
To replenish the lost salts and water due to diarrhoea, take ORS and plenty of fluids.
Do not skip doses and finish the prescribed course, even if you start feeling better.
Stopping it early may increase the risk of further infection.
Discontinue Nizonide 500 Tablet and inform your doctor immediately if you develop a rash, itchy skin, swelling of face and mouth, or has difficulty in breathing.
Never save the medicine for future illnesses because its effectiveness in future infections cannot be guaranteed.
Never share the medicines as it causes harm unless prescribed.
Miscelleneous
How it works
Nizonide 500 Tablet interferes with the energy production of the parasites/protozoa and prevents its growth that causes diarrhoea.
Legal Status
Classification
Category
Anti-parasitic Agents, Antiprotozoals
Schedule
Schedule H
Pubchem.ncbi.nlm.nih.gov. 2021. Nitazoxanide. [online] Available at: < [Accessed 20 August 2021].
Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 20 August 2021].
Drugs, H., 2021. Nitazoxanide: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 August 2021].
Dailymed.nlm.nih.gov. 2021. DailyMed - ALINIA- nitazoxanide tabletALINIA- nitazoxanide powder, for suspension. [online] Available at: < [Accessed 20 August 2021].
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Information on this page was last updated on 24 Aug 2021
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.
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