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Pregaba-Forte Capsule

Manufactured byUnichem Laboratories Ltd.
ContainsAlpha lipoic acid (100 mg) + (1.5 mg) + Methylcobalamin (750 mcg) + Pregabalin (75 mg) + Pyridoxine (3 mg)
CURRENTLY UNAVAILABLE

Description

Pregaba-Forte Capsule is a combination of Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Pyridoxine. It is used in the treatment of diabetic neuropathy (nerve damage due to diabetes). This medicine works by blocking the transfer of pain signals from the damaged nerves. It also helps to repair the damaged nerves. Pregaba-Forte Capsule shows side effects like nausea, vomiting, headache, skin rash, indigestion, etc. These side effects usually subside with time as your body adjusts to the medicine. However, consult your doctor if any of these side effects persist or become severe. Avoid driving vehicles or operating machines if you feel dizzy or drowsy after taking this medicine. Pregaba-Forte Capsule can be taken with or without food as instructed by your doctor. Avoid the discontinuation of this medicine without consulting your doctor as it may worsen your condition. Pregaba-Forte Capsule is not recommended for use if you are allergic to it, or if you have Leber's disease (a rare genetic disorder that occurs due to the death of optic nerve cells in the eyes leading to painless loss of vision). Inform your doctor if you are taking any other medicine, or have any other medical condition before starting the treatment with Pregaba-Forte Capsule. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Substitutes

List of substitutes for Pregaba-Forte Capsule

Side effects

Major & minor side effects for Pregaba-Forte Capsule

Nausea and vomiting

Loss of appetite

Skin rash

Sleepiness

Diarrhoea

Swelling of face, lips, eyelids, tongue, hands and feet

Weakness

Dry mouth

Headache

Dizziness

Uses of Pregaba-Forte Capsule

What is it prescribed for?

Diabetic Neuropathy

Diabetic Neuropathy refers to nerve damage that may occur due to diabetes (high blood sugar levels). The symptoms include pain, numbness, tingling/burning sensation, etc. in the legs. Pregaba-Forte Capsule is used for the treatment of diabetic neuropathy.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The time Pregaba-Forte Capsule takes to show show its action is not known.

  • How long do the effects of this medicine last?

    The amount of time for which Pregaba-Forte Capsule remains active in your body is not known.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with Pregaba-Forte Capsule as it may increase the risk of side effects like drowsiness, dizziness, and difficulty in concentrating. Avoid performing activities that require high mental alertness like driving vehicles or operating machines.

  • Is this a habit forming medicine?

    Pregaba-Forte Capsule has a low abuse potential with limited physical and psychological dependence.

  • Can this medicine be taken during pregnancy?

    Pregaba-Forte Capsule is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.

  • Can this medicine be taken while breast-feeding?

    Pregaba-Forte Capsule is not recommended for use while breastfeeding as it may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.

Leber's Disease

Leber's disease is a rare genetic disorder in which there is a painless loss of vision due to the death of optic nerve cells in your eyes. Pregaba-Forte Capsule is not recommended if you have Leber's disease as it may worsen your condition.

Allergy

Avoid taking Pregaba-Forte Capsule if you are allergic to it. Seek immediate medical attention if you notice symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Warnings for special population

Pregnancy

Pregaba-Forte Capsule is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.

Breast-feeding

Pregaba-Forte Capsule is not recommended for use while breastfeeding as it may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.

General warnings

Other medicines

Pregaba-Forte Capsule may interact with other medicines and cause undesired effects. Hence, inform your doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Gastrointestinal surgery

If you recently had gastrointestinal surgery, it may decrease the absorption of Pregaba-Forte Capsule into the blood. Hence, inform your doctor if you have undergone gastrointestinal surgery before starting treatment with this medicine.

Use of antacids

Coadministration of antacids and Pregaba-Forte Capsule may reduce the absorption of this medicine. Hence, take this medicine one hour before or two hours after taking antacids containing aluminum and magnesium hydroxide.

Kidney disease

Pregaba-Forte Capsule is filtered by the kidneys and removed from the body via urine. Hence, this medicine should be used with caution if you have kidney problems. Impaired kidney function may lead to the accumulation of this medicine in your body and increase the risk of side effects. Your doctor may suggest tests to closely monitor your kidney function while you are taking this medicine.

Suicidal tendencies

Pregaba-Forte Capsule may lead to change in mood or behaviour and suicidal tendencies. Report any mood changes to your doctor immediately so that counselling can be done. If the symptoms persist, your doctor may advise an alternate medicine.

Driving or operating machines

Pregaba-Forte Capsule may increase the risk of side effects like drowsiness, dizziness, difficulty in concentrating, etc. Hence, avoid performing activities such as driving vehicles or operating machines if you experience any of these symptoms.

High creatinine kinase levels

Myopathy is a condition in which the muscles do not function properly leading to muscle weakness. Pregaba-Forte Capsule should be used with caution in such conditions as this medicine causes an increase in the creatine kinase levels. Thus, it may worsen your condition.

Use in children

Pregaba-Forte Capsule is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.

Potential for abuse

Pregaba-Forte Capsule may cause dependency, especially if you have used other recreational medicines (chemical substances taken for enjoyment, or leisure purposes, rather than for medical reasons) in the past. Inform your doctor if you had a history of substance abuse before taking this medicine. Your doctor may prescribe a suitable alternative.

Missed Dose

If you forget to take a dose of Pregaba-Forte Capsule, take the missed dose as soon as you remember. However, if it is time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment if you suspect an overdose of Pregaba-Forte Capsule .
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Pregaba-Forte Capsule as it may increase the risk of side effects like drowsiness, dizziness, and difficulty in concentrating. Avoid performing activities that require high mental alertness like driving vehicles or operating machines.

Interaction with Medicine

Levodopa

Fluorouracil

Phenytoin

Phenobarbital

Disease interactions

Disease

Information not available.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Pregaba-Forte Capsule with or without food as instructed by your doctor. Do not break, chew, or crush the capsule. Avoid taking more or less than the prescribed dose. Avoid the discontinuation of Pregaba-Forte Capsule without consulting your doctor. Avoid consuming alcohol while you are taking Pregaba-Forte Capsule as it may cause undesired effects.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Pregaba-Forte Capsule is a combination of Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Pyridoxine. Alpha lipoic acid works by slowing down nerve damage and reducing symptoms like pain, tingling, and pricking in the feet and legs. Folic acid and Pyridoxine are essential for the production of certain vital components that are necessary to maintain normal body functions. Methylcobalamin helps in the production of myelin (a substance that protects the nerve fibres) and helps to heal the damaged nerve cells. Pregabalin acts by reducing certain chemical substances in the brain and interfering with the pain signals travelling through the damaged nerves and the brain. Thus, it relieves pain due to nerve damage.

Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Gamma-aminobutyric acid analogs, Vitamins

Schedule

Schedule H

Encyclopedia, M. and B12, V., 2021. Vitamin B12: MedlinePlus Medical Encyclopedia. [online] Medlineplus.gov. Available at: [Accessed 6 September 2021].

https://medlineplus.gov/ency/article/002403.htm

Drugs, H., 2021. Pyridoxine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 6 September 2021].

https://medlineplus.gov/druginfo/meds/a682587.html

Drugs, H., 2021. Folic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 14 September 2021].

https://medlineplus.gov/druginfo/meds/a682591.html

Drugs, H. and Supplements, H., 2021. Alpha-Lipoic Acid: MedlinePlus Supplements. [online] Medlineplus.gov. Available at: [Accessed 15 September 2021].

https://medlineplus.gov/druginfo/natural/767.html

Pubchem.ncbi.nlm.nih.gov. 2021. Pregabalin. [online] Available at: [Accessed 14 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Pregabalin

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Information on this page was last updated on 27 Feb 2023

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