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Pronjep Tablet

Manufactured byBLUBELL PHARMA
ContainsAlprazolam (0.25 mg) + Propranolol (20 mg)
CURRENTLY UNAVAILABLE

Description

Pronjep Tablet is a combination medicine which may be used to treat anxiety, panic disorders like unexpected extreme fear and tension due to stress, and prevention of migraine. It is also used for treating high blood pressure and relieving tremors in anxiety patients. Do not stop taking this medicine suddenly as it may cause withdrawal symptoms like seizures, aggressive behavior, blurred vision, etc.
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Side effectsConcernsUsage

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Substitutes

List of substitutes for Pronjep Tablet

Side effects

Major & minor side effects for Pronjep Tablet

Difficulty in breathing

Weight gain

Unsteadiness

Changes in pattern of speech

Loss of coordination

Drowsiness

Diarrhea

Skin blistering

Swelling of face, lips, eyelids, tongue, hands and feet

Irregular heartbeat

Blurred vision

Abdominal pain

Chest pain and discomfort

Acid or sour stomach

Heartbun

Uses of Pronjep Tablet

What is it prescribed for?

Hypertension

This medicine is used for the management of hypertension, which is an increase in the blood pressure levels in patients who are suffering from anxiety.

Anxiety

This medicine may be used in the treatment of anxiety which is characterized by feelings of tension, worried thoughts and physical changes like increased blood pressure. uneasiness, difficulty in sleeping, sweating of hands and feet, etc.

Panic attacks

This medicine may be used in the prevention and management of panic attacks which involve sudden extreme fear without warning, sweating, breathing problem, chest pain, etc.

Essential tremor

This medicine is used to treat the symptoms of tremor, where a part of the body starts to shake without any control.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of this medicine can be observed within 1 to 2 hours of administration of the dose.

  • How long do the effects of this medicine last?

    The effect of this medicine lasts for an average duration of 44 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious adverse effects. These side effects may include dizziness, drowsiness, difficulty concentrating, breathing difficulties, etc. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.

  • Is this a habit forming medicine?

    Use of this medicine may cause habit-forming tendencies which were reported in some cases especially if the usage is for an extended period of time. A gradual withdrawal of the drug i.e. decrease in dosing over a period of time is suggested in such cases.

  • Can this medicine be taken during pregnancy?

    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

  • Can this medicine be taken while breast-feeding?

    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to alprazolam, propranolol or any other inactive ingredients present in the formulation

Asthma

This medicine is not recommended for use if you have asthma or other obstructive diseases of the lung due to the increased risk of worsening of the patient's condition.

Heart Failure

This medicine is not recommended for use in patients who have severe heart failure and are getting emergency attention due to the increased risk of worsening of the patient's condition.

Heart rhythm disorders

This medicine is not recommended for use in patients having a significant decrease in heart rate due to the increased risk of worsening of the patient's condition.

CYP3A4 inhibitors

This medicine is not recommended for use in patients who are concomitantly taking CYP3A4 inhibitors such as itraconazole, ketoconazole, etc due to the increased risk of worsening of the patient's condition.

Acute narrow-angle glaucoma

This medicine is not recommended for use in patients with acute narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

General warnings

Heart failure

Use of this medicine should be done with caution due to the increased risk of heart failure, especially in people having a heart disease. Suitable dose adjustment and safety monitoring might be required based on the severity of the disease.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Sports

Athletes are advised to not indulge in certain sports while using this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency (WADA) which are not to be taken while participating in specific sports events.

Other medicines

This combination medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Elderly population

This medicine should be used with extreme caution in individuals who are 60 years old and above due to the increased risk of sedation and muscle weakness.

Impaired kidney/liver function

This medicine should be used with caution in individuals with impaired kidney/liver function due to the increased risk of adverse effects. Close monitoring of liver/kidney function tests is necessary while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. Patients should be closely monitored for any change in mood or behavior. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Drug Abuse

This medicine should be used with caution in patients with a known history of drug abuse. Chances of dependency are very high, especially if the intended use is for a long duration of time. Patients should be monitored closely for any changes in mood and behavior and any drug-seeking behavior; any such changes should be reported to the doctor immediately.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious adverse effects. These side effects may include dizziness, drowsiness, difficulty concentrating, breathing difficulties, etc. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.

Interaction with Medicine

Opioids

Formoterol

Epinephrine

Lidocaine

Amlodipine

Cetirizine

Aminophylline

Diltiazem

Metoclopramide

Disease interactions

Asthma

This medicine is not recommended for use in patients with asthma due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered in some cases based on the clinical condition.

Heart disease

This medicine should be used with extreme caution in patients with heart disorders due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with diabetes due to the increased risk of adverse effects. Close monitoring of blood glucose levels is advised for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Food interactions

Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
This medicine should be used with caution if you are taking vitamin and mineral supplement. Report the use of supplements to the doctor so that dose adjustments and safety monitoring can be done. There should be a gap of at least 2 hours between the consumption of these two medicines.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by your doctor. You may take this medicine with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works

Alprazolam works by decreasing the uncontrolled, excitatory activity in the brain. Propranolol works by relaxing the blood vessels and slowing the heartbeat. It also helps in relieving anxiety and tension.

Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Non-cardioselective beta blockers, Benzodiazepines

Schedule

Schedule H

DailyMed - alprazolam tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 23 February 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2238e083-08f2-0aa8-59b7-16b6d68dbd48

Alprazolam: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 23 February 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a684001.html

DailyMed - propranolol hydrochloride capsule, extended release [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a4edba76-29b8-41fb-bf0b-d4633abba003

propranolol | C16H21NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/4946#section=Top

Related Questions

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Information on this page was last updated on 2 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.