✕

Download the Practo app for free

Get Rs. 200 HealthCash
Download the app now
✔ Book instant appointments 24x7
✔ Bookmark doctors for quick access
✔ Consult online with a doctor in 60s
✕
Free ₹200 worth HealthCash on app
Use HealthCash to order medicines, health products & much more
Get App

Refract 100 MG Tablet

Manufactured byCrescent Formulations Pvt. Ltd.
ContainsClozapine
CURRENTLY UNAVAILABLE

Description

Refract 100 MG Tablet is an antipsychotic medication that is used in the treatment of Schizophrenia (a disorder that affects your ability to think, feel and behave clearly). It works by changing the effects of chemicals in the brain. Refract 100 MG Tablet may cause side effects like agranulocytosis (a rare condition in which your bone marrow does not make enough white blood cells), drowsiness, sedation, sleeplessness, tremors, excessive salivation, constipation, weight gain, irregular heartbeat, etc. Most of these side effects should resolve with time. Do not discontinue the use of this medicine without consulting your doctor. Do not use this medicine if you have been allergic to Clozapine in the past. Seek immediate medical attention if you experience skin rashes, hives, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, etc. Refract 100 MG Tablet may be taken with or without food as per your doctor's instructions. Avoid consuming alcohol, driving vehicles, or operating heavy machines while undergoing treatment with this medicine. Refract 100 MG Tablet is not recommended for use while breastfeeding. Consult your doctor before using this medicine if you are pregnant or trying to get pregnant. Inform your doctor of any heart, liver, or kidney problems you may have, or if you are diabetic. Refract 100 MG Tablet is not recommended for use in children younger than 16 years of age.
QUICK LINKS:
Side effectsConcernsUsageRelated products

How will this medicine affect me?

Consult top doctors online and get an answer now.
Consult now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now

Should you be taking this medicine?

Consult with a Doctor for the best diagnosis.

Looking for a doctor?

Book an appointment with the top doctors near you

Substitutes

List of substitutes for Refract 100 MG Tablet

Clozapine 100 MG Tablet
Intas Pharmaceuticals Ltd.
Cozapine 100 MG Tablet
Mankind Pharmaceuticals Ltd.
Lozapin 100 MG Tablet
Torrent Pharmaceuticals Ltd.
Sizopin 100 MG Tablet
Sun Pharma Laboratories Ltd.
Skizoril 100 MG Tablet
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Refract 100 MG Tablet

Blurred vision

Dizziness

Fast heartbeat

Shaking of the hands or feet

Constipation

Increased salivation

Anxiety

Dry mouth

Weight gain

Acid or sour stomach

Muscle pain

Sore throat

Uses of Refract 100 MG Tablet

What is it prescribed for?

Schizophrenia

Refract 100 MG Tablet is used in the treatment of Schizophrenia which is a severe and chronic mental disorder characterized by abnormal social behavior and impaired ability to think and perceive reality clearly.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    The effect of Refract 100 MG Tablet can be observed within 15 minutes of administration of the dose.

  • How long do the effects of this medicine last?

    The amount of time for which Refract 100 MG Tablet remains active in the body is dependent on the dose and duration of treatment.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with Refract 100 MG Tablet due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, confusion, nausea, vomiting, etc. Avoid performing any activities that require high mental alertness such as driving a vehicle or operating machines if you consume alcohol during treatment with this medicine.

  • Is this a habit forming medicine?

    No habit-forming tendency has been reported for Refract 100 MG Tablet.

  • Can this medicine be taken during pregnancy?

    Refract 100 MG Tablet is not recommended for use in pregnant women unless absolutely necessary. Your doctor may weigh the risks and benefits of using this medicine before prescribing it to you.

  • Can this medicine be taken while breast-feeding?

    Refract 100 MG Tablet is not recommended for use in breastfeeding women.

Allergic reaction

Refract 100 MG Tablet is not recommended for use if you are have been allergic to Clozapine or any other inactive ingredients present in this formulation in the past. Seek immediate medical attention if you experience skin rashes, hives, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, etc.

Warnings for special population

Pregnancy

Refract 100 MG Tablet is not recommended for use in pregnant women unless absolutely necessary. Your doctor may weigh the risks and benefits of using this medicine before prescribing it to you.

Breast-feeding

Refract 100 MG Tablet is not recommended for use in breastfeeding women.

General warnings

Diabetes and Dyslipidemia

Refract 100 MG Tablet may increase the blood sugar levels and cholesterol levels in the body. Your doctor may recommend regular monitoring of your blood sugar, cholesterol, and fat levels, as well as your body weight.

Blood cells count

Refract 100 MG Tablet may reduce the blood cell count, especially WBC (neutrophils). Report any symptoms such as fever, weakness during the treatment, etc. to your doctor. Your doctor may recommend regular monitoring of your blood cell count.

Withdrawal symptoms

Abrupt discontinuation of Refract 100 MG Tablet may increase the risk of adverse effects, especially if you have been using a high dose for a long duration. Your doctor may recommend a gradual dose reduction to minimize these reactions. Do not stop the use of this medicine without consulting your doctor.

Use in children

Refract 100 MG Tablet is not recommended for use in children younger than16 years of age since the safety and efficacy of use are not clinically established.

Driving vehicles or operating machines

Refract 100 MG Tablet may cause dizziness or drowsiness in some people. Avoid performing any activities that require high mental alertness like driving a vehicle or operating machines if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Avoid missing a scheduled dose of Refract 100 MG Tablet. Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Do not take more than the prescribed dose of Refract 100 MG Tablet. Clozapine overdose may cause symptoms like drowsiness, sedation, abnormal reflexes, confusion, hallucinations, agitation, convulsions, hypersalivation, blurred vision, etc. Seek emergency medical attention or contact your doctor if you experience any of these symptoms or suspect an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Refract 100 MG Tablet due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, confusion, nausea, vomiting, etc. Avoid performing any activities that require high mental alertness such as driving a vehicle or operating machines if you consume alcohol during treatment with this medicine.

Interaction with Medicine

Ketoconazole

Tramadol

Antidiabetic drugs

Antihypertensives

Disease interactions

Dementia

Refract 100 MG Tablet is not recommended for use if you have dementia-related psychosis as it may increase the risk of heart failure or infectious diseases like Pneumonia. This risk is especially high in the geriatric population. Your doctor may recommend replacement with a suitable alternative based on your clinical condition.

Seizure disorders

Refract 100 MG Tablet should be used with caution if you have a history of seizures or conditions that lower the seizure threshold. Your doctor may recommend appropriate dose adjustment or replacement with a suitable alternative based on your clinical condition.

Liver Disease

Refract 100 MG Tablet should be used with caution if you have or had liver problems. Your doctor may recommend close monitoring of your liver function, appropriate dose adjustments, or replacement with a suitable alternative based on your clinical condition.

Kidney Disease

Refract 100 MG Tablet should be used with caution if you have or had kidney problems. Your doctor may recommend close monitoring of your kidney function, appropriate dose adjustments, or replacement with a suitable alternative based on your clinical condition.

Food interactions

Information not available.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Refract 100 MG Tablet with or without food, as instructed by your doctor. Do not break, chew or crush the tablet. Swallow as a whole with a glass of water. Follow all the directions on the prescription label/package insert. Do not take in larger or smaller amounts than prescribed. Consult your doctor if you experience any undesirable effects. Refract 100 MG Tablet is used for long-term treatment, hence it may take four to six weeks to show its effect. Do not stop taking Refract 100 MG Tablet before completion of the course. Consult your doctor if you wish to discontinue treatment. Refract 100 MG Tablet may increase your blood sugar levels, blood cholesterol levels, low blood pressure and may also cause weight gain and dehydration. Your doctor may recommend frequent monitoring of your blood pressure, blood sugar, and cholesterol levels to ensure you are healthy. Refract 100 MG Tablet may cause drowsiness or sedation in some people. Hence, it is recommended to avoid driving vehicles or operating machines immediately after taking this medicine. Avoid consuming alcohol as it can increase undesired effects like dizziness and drowsiness.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Refract 100 MG Tablet works by binding to certain receptors and inhibiting the release of the chemical substances that cause psychotic symptoms.

Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Atypical antipsychotics

Schedule

Schedule H

Medicines.org.uk. 2020. Clozaril 25 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 6 December 2021].

https://www.medicines.org.uk/emc/product/4411/smpc#PRODUCTINFO>

Accessdata.fda.gov. 2021. CLOZARIL® (clozapine) Tablets. [online] Available at: < [Accessed 6 December 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/019758s062lbl.pdf>

Medlineplus.gov. 2020. Clozapine: MedlinePlus Drug Information. [online] Available at: < [Accessed 6 December 2021].

https://medlineplus.gov/druginfo/meds/a691001.html>

Mayoclinic.org. 2021. Clozapine (Oral Route) Before Using - Mayo Clinic. [online] Available at: < [Accessed 6 December 2021].

https://www.mayoclinic.org/drugs-supplements/clozapine-oral-route/before-using/drg-20066859>

Dailymed.nlm.nih.gov. 2020. DailyMed - CLOZAPINE tablet. [online] Available at: < [Accessed 6 December 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=d5c8a456-6f3c-4963-b321-4ed746f690e4>

Related Questions

Question:
In an eye, does the angle of refraction between the vitreous humor and retina have any significance?...more
Answer from Dr. Vaibhev Mittal
Hello A.  Vitreous is attached to retina at many places so difficult to detect ...more
Question:
Is refractive surgery contraindicated in a patient of psoriasis? Even when it is just a scalp psoria...more
Answer from Dr. Anshu Arora
Yes
Question:
What's dilated refraction? How much does it cost ? Is there any harm if wear glasses (lens) of wro...more
Answer from Dr. Surya Kant Jha
pupil of your eyes will be dilated with drops to get the actual number of your e...more
Question:
Eye power is 7.25 in both eyes, which refractive surgery is suitable? Contoura lasik or icl is more ...more
Answer from Dr. A Raja Prasanna Kumar
ICL may suite you.pl consult.
Question:
I am software engineer if I go for eye surgery refractive eye surgery like lasik contura how many da...more
Answer from Dr. Neelima Y
24-48hours strict NO. Atleast 1week rest from using screen.  There will be mild ...more
Something doesn’t feel right?
Report an error

Information on this page was last updated on 17 Jan 2022

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.