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Augmentin 1000 Duo Tablet

Manufactured byGlaxosmithkline Pharmaceuticals Ltd.
ContainsAmoxycillin (875 mg) + Clavulanic Acid (125 mg)
Description
Augmentin 1000 Duo Tablet is a combination medicine that consists of Amoxycillin and Clavulanic acid. Augmentin 1000 Duo Tablet is used to treat bacterial infections of the lungs and airways, middle ear, sinuses, skin, and urinary tract. Amoxycillin interferes with the growth and division process of the bacterial cell wall while clavulanic acid enhances the activity of Amoxycillin in treating infections caused by susceptible bacteria. Augmentin 1000 Duo Tablet shows common side effects like nausea, vomiting, stomach pain, and skin rash. Usually, these side effects are self-limiting. Consult your doctor at the earliest if any of these effects persist for a long time or worsen. Inform your doctor if you are allergic to this medicine or any other antibiotics. Augmentin 1000 Duo Tablet should be taken with food as it improves absorption and decreases the risks of stomach upset. Your doctor will decide the dose and frequency based on the severity of the infection. Stick to the dose, time, and way prescribed. Also, ensure to complete the course of treatment even if you feel better after taking few doses of this medicine. Stopping the use of this medicine early may make the infection come back and harder to treat. Augmentin 1000 Duo Tablet is not recommended if you are having conditions like liver problems like cholestasis ( a condition where the normal flow of bile from the liver is interrupted). This medicine may cause dizziness and sleepiness. Avoid driving or operating machines if you feel dizzy or sleepy. Augmentin 1000 Duo Tablet can make birth control pills less effective. You may be advised to follow different birth control methods to prevent unintended pregnancy. Augmentin 1000 Duo Tablet may interact with other medicines and may not be safe for use in certain medical conditions. Share your entire medical history with your doctor, including any previous episode of allergy, heart problem, a blood disorder, lung problem, stomach or intestinal problem, skin disorder, liver or kidney problems. This information is critical as it can help your doctor in planning an overall treatment for you. Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding.

Side effects

Major & minor side effects for Augmentin 1000 Duo Tablet

  • Allergic Skin Reaction
  • Diarrhoea
  • Joint pain
  • Skin yellowing
  • Easy bruising and bleeding
  • Heavy menstrual bleeding
  • Tooth discoloration
  • Nausea or vomiting
  • Altered sense of taste
  • Dizziness
  • Painful intercourse
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Black or tarry stools
  • Muscle or joint pain
  • Sleeplessness
  • Irregular heartbeat

Uses of Augmentin 1000 Duo Tablet

What is it prescribed for?

  • Ear infection
  • Sinusitis
  • Pharyngitis/Tonsilitis
  • Lower respiratory tract infection
  • Skin infections
  • Urinary tract infection
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Augmentin 1000 Duo Tablet can be observed within 1-2 hours after taking it.
  • How long do the effects of this medicine last?
    The effect of Augmentin 1000 Duo Tablet lasts for an average duration of 6-8 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Augmentin 1000 Duo Tablet has no habit forming tendency.
  • Can this medicine be taken during pregnancy?
    Augmentin 1000 Duo Tablet should be used in pregnant women only if clearly needed. Your doctor may prescribe this medicine if the benefits outweigh the risks.
  • Can this medicine be taken while breast-feeding?
    Augmentin 1000 Duo Tablet pass into the breastmilk in low levels that are not expected to cause any harmful effects in infants. However, consult your doctor before taking this medicine.

Allergy

Avoid taking Augmentin 1000 Duo Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms like skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Cholestasis

Avoid taking Augmentin 1000 Duo Tablet if you have cholestasis (a condition where the normal flow of bile from the liver is interrupted).

Liver dysfunction

Avoid taking Augmentin 1000 Duo Tablet if you have a history of liver problems associated with the use of this medicine or any other antibiotics.
Warnings for special population

Pregnancy

Augmentin 1000 Duo Tablet should be used in pregnant women only if clearly needed. Your doctor may prescribe this medicine if the benefits outweigh the risks.

Breast-feeding

Augmentin 1000 Duo Tablet pass into the breastmilk in low levels that are not expected to cause any harmful effects in infants. However, consult your doctor before taking this medicine.
General warnings

Allergic reaction

Augmentin 1000 Duo Tablet is likely to cause moderate to a severe allergic reaction and the likelihood is very if you have an antibiotic allergy. Report to your doctor on priority if you notice any allergic reactions.

Diarrhoea

Augmentin 1000 Duo Tablet can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Get emergency medical help if you experience severe diarrhoea that is watery or bloody.

Antibiotic-resistance

The entire course of treatment with Augmentin 1000 Duo Tablet should be completed, even if the condition gets better after receiving a few doses, due to the chances of antibiotic resistance (a condition where microbes evolve mechanisms that protect them from the effects of antibiotics).

Liver disease

Augmentin 1000 Duo Tablet may increase liver enzyme levels and cause liver swelling. If you have liver problems, you need special consideration while taking Augmentin 1000 Duo Tablet due to the risk of liver damage. Your doctor may adjust the dose of this injection and may closely monitor your liver functioning if required, based on your clinical condition.

Dosing consideration

Augmentin 1000 Duo Tablet is normally given when the infection is very severe and lower dose strengths are proving to be ineffective.

Use in children

Augmentin 1000 Duo Tablet should not be used in children under 12 years of age as the safety and efficacy data are not available.

Driving and operating machines

Augmentin 1000 Duo Tablet may cause dizziness and sleepiness in some people. Avoid driving or operating machines if you feel dizzy or sleepy.

Missed Dose

If you forget Augmentin 1000 Duo Tablet dose, make sure that you remember to take your next dose on time. Do not take two doses together to make up for a forgotten dose.

Overdose

Never take Augmentin 1000 Duo Tablet more than the prescribed dose. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Doxycycline

Methotrexate

Warfarin

Ethinyl Estradiol

Live vaccines

Disease interactions

Mononucleosis

Augmentin 1000 Duo Tablet may not be appropriate medicine in people with mononucleosis. as they (kissing disease- transmitted by saliva) may develop a maculopapular skin rash after 5-10 days of treatment with this medicine. This condition resolves within days of discontinuing the use.

Colitis

Augmentin 1000 Duo Tablet can kill the helpful bacteria in your stomach or intestine and lead to diarrhoea. Therefore, use this medicine with extreme caution if you have colitis (swelling of the colon's inner lining).

Kidney diseases

People with kidney problems need special consideration while taking Augmentin 1000 Duo Tablet due to the risk of kidney damage. Dose adjustment should be done based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Urine Sugar Test (Benedict's of Fehling's reagent)

Report the use of Augmentin 1000 Duo Tablet prior to the test. This medicine may give a false-positive result for the presence of glucose/sugar in the urine.
Take Augmentin 1000 Duo Tablet with food to avoid stomach upset. Finish the prescribed course of Augmentin 1000 Duo Tablet even if you start to feel better. Stopping it early may make the infection come back and harder to treat. Diarrhoea may occur as a side effect. Taking probiotics along with Augmentin 1000 Duo Tablet may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps. Stop taking Augmentin 1000 Duo Tablet and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it. Do not use leftover medicine for treating any infection in the future. Always consult your doctor before taking any antibiotic. Do not crush, break or chew the tablet in the mouth. Consume the tablet immediately after peeling it from the strip. Keep the medicine away from the reach of children and pets.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Augmentin 1000 Duo Tablet is a combination of Amoxycillin and Clavulanic acid. Amoxycillin binds to certain specific receptors and prevents the formation of a necessary component for the cell wall building process. Clavulanic acid is effective against a specific species of bacteria that are resistant to other antibiotic medicines. Thus, the combination becomes effective against an extended range of bacteria.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Beta-lactamase inhibitors, Aminopenicillins

Schedule

Schedule H

Drugs, H., 2021. Amoxicillin and Clavulanic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 May 2021].

https://medlineplus.gov/druginfo/meds/a685024.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - AMOXICILLAN AND CLAVULANATE POTASSIUM tablet, film coated. [online] Available at: < [Accessed 20 May 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=909c85de-c076-4444-b63c-cd8bdc556f36>

Pubchem.ncbi.nlm.nih.gov. 2021. Clavulanic acid. [online] Available at: < [Accessed 20 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clavulanic-acid>

Pubchem.ncbi.nlm.nih.gov. 2021. Amoxicillin. [online] Available at: < [Accessed 22 January 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Amoxicillin>
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Information on this page was last updated on 25 Oct 2021

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