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Clofranil 25 MG Tablet
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Clofranil 25 MG Tablet

Manufactured bySun Pharma Laboratories Ltd.
ContainsClomipramine
Description
Clofranil 25 MG Tablet is a tricyclic antidepressant medicine, used in the treatment of psychological conditions like obsessive-compulsive disorder, depression and anxiety disorders like panic attacks. It is also used in the treatment of muscle weakness associated with a sleep disorder called narcolepsy. It works by increasing the levels of a chemical substance called serotonin in the brain that helps in regulating mood and treating depression. Clofranil 25 MG Tablet may cause some common side effects like dry mouth, nausea, vomiting, loss of appetite stomach upset, indigestion and, constipation. Do not drive vehicles or operate machines as it may cause dizziness and drowsiness. It may cause intense vertigo or dizziness when you suddenly stand up, so it is advised that you rise slowly and with support, if you have been sitting or lying positions. It may also lead to weight gain in some people. Inform your doctor if any of these side effects persist or worsen. Clofranil 25 MG Tablet should be taken with food or as prescribed by your doctor. Take this medicine every day at the same time for the ease of remembering. Do not stop taking this medicine without consulting your doctor as it may cause withdrawal symptoms and even cause changes in your mood. Clofranil 25 MG Tablet may not be suitable for all people. It is not recommended for use in children below the age of 12 years. Avoid taking this medicine if you have liver problems. Inform your doctor of your complete medical history and list of medicines you are currently taking before beginning treatment with Clofranil 25 MG Tablet. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding before taking this medicine.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Clofranil 25 MG Tablet

Anafranil 25 MG Tablet
Novartis India Ltd.
Clonil 25 MG Tablet
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Clofranil 25 MG Tablet

  • Dizziness
  • Blurred vision
  • Dry mouth
  • Nausea or Vomiting
  • Swelling of face and feet
  • Acid or sour stomach
  • Constipation
  • Shaking of hands or feet
  • Mouth ulcers
  • Irregular menstrual periods

Uses of Clofranil 25 MG Tablet

What is it prescribed for?

  • Obsessive Compulsive Disorder
  • Depression
  • Cataplexy associated with narcolepsy
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Clofranil 25 MG Tablet to start showing its effect is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Clofranil 25 MG Tablet remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consuming alcohol while taking Clofranil 25 MG Tablet as it can increase the risk of serious side effects such as difficulty concentrating and dizziness.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Clofranil 25 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Clofranil 25 MG Tablet is not recommended for use in pregnancy unless necessary. If you are pregnant, consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Clofranil 25 MG Tablet is not recommended for use in breastfeeding unless necessary. If you are breastfeeding, consult your doctor before taking this medicine.

Allergy

Avoid taking Clofranil 25 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, as well as any behavioural changes and suicidal thoughts.

Monoamine oxidase inhibitors (MAOI)

Monoamine oxidase inhibitors (MAOIs) are the medicines used in the treatment of depression. Clofranil 25 MG Tablet is not recommended for use if you are taking Monoamine Oxidase Inhibitors (MAOIs). There should be a time gap of at least 14 days between stopping treatment with MAOIs and beginning treatment with this medicine to avoid their interaction.
Warnings for special population

Pregnancy

Clofranil 25 MG Tablet is not recommended for use in pregnancy unless necessary. If you are pregnant, consult your doctor before taking this medicine.

Breast-feeding

Clofranil 25 MG Tablet is not recommended for use in breastfeeding unless necessary. If you are breastfeeding, consult your doctor before taking this medicine.
General warnings

Suicidal thoughts

Clofranil 25 MG Tablet may increase the risk of suicidal thoughts and behaviour in children, adolescents, and young adults (age between 18 to 24) with major depressive disorder (MDD) and other psychiatric conditions. Consult your doctor if you observe any changes in mood or behaviour.

Serotonin Syndrome

Serotonin syndrome is when your body has too much of a chemical called serotonin, usually because of a medication. Clofranil 25 MG Tablet may cause serotonin syndrome. Immediate medical treatment should be initiated if any symptoms of agitation, hallucinations, dizziness, tremor, seizures, nausea, and vomiting appear.

Changes in weight

Clofranil 25 MG Tablet is known to cause either weight loss or weight gain. Inform your doctor if you experience any changes in body weight.

Withdrawal Symptoms

Clofranil 25 MG Tablet may cause withdrawal symptoms if the usage is stopped abruptly. This risk is especially higher after prolonged usage of this medicine. The treatment should be withdrawn gradually under the close supervision of your doctor. Do not stop the use of this medicine without consulting your doctor.

Driving or operating machines

Clofranil 25 MG Tablet may cause drowsiness or dizziness in some people. Hence, do not perform activities that require high mental alertness like driving vehicles or operating machinery if you experience any of these symptoms after taking this medicine.

Missed Dose

Take the missed dose of Clofranil 25 MG Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose of Clofranil 25 MG Tablet is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consuming alcohol while taking Clofranil 25 MG Tablet as it can increase the risk of serious side effects such as difficulty concentrating and dizziness.
Interaction with Medicine

Tramadol

Antihypertensives

CNS depressants

Quinidine

Coumarin

Adrenaline

Anticholinergic medicines

Disease interactions

Seizures

Use Clofranil 25 MG Tablet is not recommended for use if you have seizures as it may trigger an episode or worsen your condition. An alternative medicine or dose adjustments should be made under doctor supervision. Do not stop the use of any medicine without consulting your doctor. Report any unusual symptoms to the doctor immediately. The risk is higher in the presence of brain trauma, use of neuroleptics, withdrawal from alcohol or drugs with anticonvulsive properties (e.g. benzodiazepines).

Diabetes

Clofranil 25 MG Tablet should be used with caution if you have diabetes due to the increased risk of altered blood glucose levels. Your doctor may suggest regular tests for monitoring your blood glucose levels. Also, your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

Glaucoma

Glaucoma is a condition where the pressure in the eyeballs is abnormally high that can damage the optic nerve and lead to eventual loss of vision. Clofranil 25 MG Tablet should be used with caution if you have a history of glaucoma due to the increased risk of worsening your condition.

Liver disease

Clofranil 25 MG Tablet should be used with caution if you have liver problems due to the increased risk of severe side effects. Your doctor may suggest tests for monitoring your liver function while you are taking this medicine. Also, he/she may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

Kidney diseases

Clofranil 25 MG Tablet should be used with caution if you have kidney problems due to the increased risk of severe side effects. Your doctor may suggest tests for monitoring your kidney function while you are taking this medicine. Also, he/she may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

Heart diseases

Clofranil 25 MG Tablet should be used with caution if you have any heart or blood vessel disorders. Your doctor may suggest tests for monitoring your heart function while you are taking this medicine. Also, he/she may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Clofranil 25 MG Tablet as it can delay the absorption of this medicine.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Clofranil 25 MG Tablet as prescribed by your doctor. Do not take more or fewer doses than prescribed. Do not stop using this medicine without consulting your doctor. Consult your doctor if you experience any undesirable effects after taking this medicine. Keep away from the reach of children and pets. Ensure that unused medicine is disposed of properly.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Causes sleepiness

How it works
Clofranil 25 MG Tablet works by increasing the levels of a chemical substance called serotonin in the brain that helps in regulating the mood and treats depression, anxiety attacks and OCD, thereby helping restore normal brain function.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Tricyclic antidepressants

Schedule

Schedule H

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https://medlineplus.gov/druginfo/meds/a697002.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Clomipramine. [online] Available at: < [Accessed 30 November 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clomipramine>

Medsafe.govt.nz. 2021. [online] Available at: < [Accessed 30 November 2021].

https://www.medsafe.govt.nz/profs/Datasheet/a/Apoclomipraminetab.pdf>

Guildlink.com.au. 2021. [online] Available at: < [Accessed 30 November 2021].

http://www.guildlink.com.au/gc/ws/nv/pi.cfm?product=nvpanfor10415>

Guildlink.com.au. 2021. [online] Available at: < [Accessed 30 November 2021].

http://www.guildlink.com.au/gc/ws/nv/cmi.cfm?product=nvcanfor10415>

Deputyprimeminister.gov.mt. 2021. [online] Available at: < [Accessed 30 November 2021].

https://deputyprimeminister.gov.mt/en/poyc/Documents/another/clomipramine.pdf>
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Information on this page was last updated on 6 Dec 2021

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