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Cof-ryl Cough Syrup
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Cof-ryl Cough Syrup

Manufactured byCIPLA LTD
ContainsDiphenhydramine (14.08 mg/5 ml) + Ammonium Chloride (138 mg/5 ml) + Sodium Citrate (57.03 mg/5 ml) + Menthol (1.14 mg/5 ml)
Description
Cof-ryl Cough Syrup is a combination medicine that consists of Diphenhydramine, Ammonium chloride, Sodium citrate and Menthol. It is used to treat cough from allergies and lung infections. It relieves allergy symptoms like runny nose, watery eyes, itchy nose and sneezing. This syrup stops certain substances produced by the body which cause allergic cough. It also dissolves the thick mucus, makes it easier to cough out the mucus made in your chest (phlegm). Cof-ryl Cough Syrup can cause some side effects like dizziness, sleepiness and stomach pain. Most of these are temporary and usually resolve with time. Consult your doctor if these symptoms bother you. Avoid any activities that require concentration as this medicine can cause drowsiness, dizziness and lack of concentration. Cof-ryl Cough Syrup can be taken with or without food. You can drink some warm water after taking it to relieve congestion in the throat. If your condition does not improve or gets worse, you should talk to your doctor. Cof-ryl Cough Syrup is not recommended for use in pregnancy and/or breastfeeding. Inform your doctor if you have kidney problems or lung diseases before taking this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Cof-ryl Cough Syrup

  • Stomach pain
  • Dizziness
  • Dry mouth
  • Sleepiness or unusual drowsiness
  • Nausea or vomiting
  • Headache
  • Skin rash

Uses of Cof-ryl Cough Syrup

What is it prescribed for?

  • Cough
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effects of Cof-ryl Cough Syrup can be seen in 15-30 minutes.
  • How long do the effects of this medicine last?
    The effects of Cof-ryl Cough Syrup can last for 4-6 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while taking Cof-ryl Cough Syrup because it may increase the risk of side effects like confusion, dizziness, and impaired judgment.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Cof-ryl Cough Syrup.
  • Can this medicine be taken during pregnancy?
    Cof-ryl Cough Syrup is not recommended if you are pregnant as it can cause serious foetal side effects. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Cof-ryl Cough Syrup is not recommended for use in breastfeeding as may harm your baby. Consult your doctor before taking this medicine.

Allergy

Avoid using Cof-ryl Cough Syrup if you are allergic to it. Seek immediate medical attention if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Hypercapnia

Hypercapnia is a condition of too much carbon dioxide (CO2) in the bloodstream. It occurs when you are not able to breathe properly and get oxygen into the lungs. Cof-ryl Cough Syrup is not recommended for use if you have hypercapnia as it may worsen your condition.
Warnings for special population

Pregnancy

Cof-ryl Cough Syrup is not recommended if you are pregnant as it can cause serious foetal side effects. Consult your doctor before taking this medicine.

Breast-feeding

Cof-ryl Cough Syrup is not recommended for use in breastfeeding as may harm your baby. Consult your doctor before taking this medicine.
General warnings

Other medicines

Cof-ryl Cough Syrup may interact with many other medicines. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Driving or operating heavy machinery

Cof-ryl Cough Syrup may cause dizziness, confusion, or fits in some people. Do not drive a vehicle or operate machinery after taking this medicine.

Ammonia toxicity

Cof-ryl Cough Syrup may cause an excess amount of ammonia levels in the blood leading serious side effects.

Missed Dose

If you forget to take a dose of Cof-ryl Cough Syrup, take it as soon as possible. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical attention if you suspect that you might have taken an overdose of Cof-ryl Cough Syrup.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking Cof-ryl Cough Syrup because it may increase the risk of side effects like confusion, dizziness, and impaired judgment.
Interaction with Medicine

Linezolid

Morphine

CNS depressants

Warfarin

Disease interactions

Depression

If you have depression disorder, close monitoring is needed for any changes in mood or behaviour while receiving Cof-ryl Cough Syrup. This medicine may worsen the depressive symptoms and may lead to suicidal thoughts.

Kidney diseases

Your doctor may adjust the dose of Cof-ryl Cough Syrup if you have kidney disease as it may lead to kidney damage.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Cof-ryl Cough Syrup with or without food. Never take more than the prescribed dose. You can drink some warm water after taking it to loosen the congestion in the throat. Consult your doctor if any unusual side effects persist after taking this medicine. Keep the medicine out of reach of children and pets. Ensure that unused medicine is disposed of properly. Do not share your medicine with other people even if their symptoms appear to be the same as yours.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Diphenhydramine stops the action of certain substances produced by the body which cause allergic reactions. Ammonium chloride clear or expel out the mucus from the congested nasal passage by inducing cough. Sodium citrate dissolves thick mucus so which makes it easier to cough out the phlegm. Menthol causes a feeling of coolness and relieves minor throat irritation.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antihistamines, Cough preparations

Schedule

Schedule H

Drugs, H., 2021. Diphenhydramine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 August 2021].

https://medlineplus.gov/druginfo/meds/a682539.html>

Drugs, H., 2021. Diphenhydramine Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 August 2021].

https://medlineplus.gov/druginfo/meds/a601044.html>

Dmpharma.co.in. 2021. D M Pharma- Diphenhydramine HCl, Ammonium Chloride, Sodium Citrate and Menthol Syrup. [online] Available at: < [Accessed 27 August 2021].

http://www.dmpharma.co.in/Ammonium%20Chloride%20+%20Diphenhydramine%20Hcl%20%20+%20Menthol%20+%20Sodium%20Citrate%20Syrup.html>

Pubchem.ncbi.nlm.nih.gov. 2021. Sodium citrate. [online] Available at: < [Accessed 27 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Sodium-citrate>
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Information on this page was last updated on 31 Aug 2021

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