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Corex DX Syrup
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Corex DX Syrup

Manufactured byPFIZER LTD
ContainsDextromethorphan (10 mg/5 ml) + Chlorpheniramine (4 mg/5 ml)
Description
Corex DX Syrup is a combination medicine consists of dextromethorphan and chlorpheniramine. It is used to treat dry cough. It is also an effective medication for the treatment of allergic symptoms like sneezing, runny nose, throat irritation, watery eyes, and redness of the nose. Corex DX Syrup reduces the activity of the cough centre in the brain and by stopping the effects of histamine that causes allergic symptoms. Corex DX Syrup show some side effects such as drowsiness, constipation, sweating, shortness of breath, dizziness, nausea and vomiting. Consult your doctor if these symptoms persist or bother you. Do not drive a vehicle or operate machinery after taking this medicine as it can cause drowsiness and dizziness. Avoid using this syrup if you are previously allergic to it. Corex DX Syrup can be taken with or without food at the dose and duration that has been prescribed. Do not stop using it without consulting your doctor as abrupt discontinuation of this medicine may cause your symptoms to recur. If you still feel unwell after completing the treatment course, consult your doctor. Corex DX Syrup is not recommended to use if you have ulcers, liver or kidney diseases as it can worsen your condition. It is recommended to consult your doctor before using Corex DX Syrup if you are pregnant or breastfeeding. It is not recommended to use this medicine in children under 6 years of age. Corex DX Syrup can affect your ability to think and may worsen drowsiness and dizziness if taken with alcohol so it is recommended to avoid consuming alcohol while using this medicine. Take it only as prescribed by your doctor because it can cause addiction or dependence with unregulated use.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Corex DX Syrup

  • Confusion
  • Constipation
  • Dizziness
  • Drowsiness
  • Headache
  • Nausea or Vomiting
  • Stomach pain
  • Blurred or double vision
  • Dry mouth

Uses of Corex DX Syrup

What is it prescribed for?

  • Dry Cough
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Corex DX Syrup starts showing its effects within 30 minutes after taking it.
  • How long do the effects of this medicine last?
    The effects of Corex DX Syrup last for an average duration of 6-7 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while taking Corex DX Syrup since it may increase the risk of side effects like confusion, dizziness, and impaired judgment.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Corex DX Syrup
  • Can this medicine be taken during pregnancy?
    Corex DX Syrup is not recommended for use in pregnancy due to the risk of harmful effects on your foetus. Consult your doctor to discuss potential risks and benefits.
  • Can this medicine be taken while breast-feeding?
    Corex DX Syrup is not recommended for use in breastfeeding. An alternate medicine may be preferred. Consult your doctor to discuss potential risks and benefits.

Allergy

Avoid using Corex DX Syrup if you are previously allergic to it. Seek immediate medical attention if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), dizziness, breathing difficulty, etc.

Benign prostatic hyperplasia

Benign prostatic hyperplasia is the enlargement of the prostate gland (the gland that produces fluid containing sperm) in males. It can cause difficulty in passing urine or cause you to have frequent urges for urination. Corex DX Syrup is not recommended for use in patients with benign prostatic hyperplasia because it may cause high difficulty in passing urine.

Monoamine oxidase inhibitors (MAOI)

Monoamine oxidase inhibitors (MAOI) are medicines used in the treatment of depression. Use of Corex DX Syrup is not recommended to use within 14 days after taking MAO inhibitors like selegiline or rasagiline. Using these medicines simultaneously may increase the risk of undesirable effects like drowsiness and blurred vision.
Warnings for special population

Pregnancy

Corex DX Syrup is not recommended for use in pregnancy due to the risk of harmful effects on your foetus. Consult your doctor to discuss potential risks and benefits.

Breast-feeding

Corex DX Syrup is not recommended for use in breastfeeding. An alternate medicine may be preferred. Consult your doctor to discuss potential risks and benefits.
General warnings

Emphysema

Emphysema is a condition of damage in the walls of the air sacs of the lungs. Corex DX Syrup should be used with caution if you suffer from emphysema as it may worsen your condition. This medicine does not expel mucus from the lungs and airways in emphysema.

Chronic bronchitis

Chronic bronchitis is a condition that affects the bronchial tubes (carries air to and from your lungs) characterized by breathing difficulty. Corex DX Syrup should be used with caution in such a condition as it may rarely cause breathing difficulty. Your doctor may adjust the dose or suggest alternate medicine based on your condition.

Kidney diseases

Use Corex DX Syrup with caution If you have kidney diseases because any impairment in kidney function can lead to its accumulation and toxicity. Your doctor may adjust the dose or suggest alternate medicine based on your condition.

Driving or operating heavy machinery

Corex DX Syrup may cause blurred vision, dizziness, or drowsiness. If you experience any of these symptoms while taking this medication, it is advised to avoid driving a vehicle or operating machinery.

Use in children

Corex DX Syrup is not generally considered to be safe or effective in children younger than 6 years. Consult the doctor before giving this medicine to your child.

Angle-closure glaucoma

Angle-closure glaucoma is a blockage of drainage canals in your eyes which leads to an increase in fluid pressure within the eye. Corex DX Syrup should be used with caution if you have angle-closure glaucoma as this medicine may even increase the eye pressure. Consult your doctor before taking this medicine.

Liver diseases

Use Corex DX Syrup with caution if you have liver disease due to the risk of worsening your condition. Your doctor may adjust the dose or suggest alternate medicine based on your condition.

Missed Dose

Take the missed dose of Corex DX Syrup as soon as you remember. If your next dosage is near, skip the missed dose. Do not double your dose to compensate for a missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention if you suspect that you might have taken an overdose of Corex DX Syrup.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking Corex DX Syrup since it may increase the risk of side effects like confusion, dizziness, and impaired judgment.
Interaction with Medicine

Escitalopram

Metoclopramide

Ondansetron

Alprazolam

Isocarboxazid

Perphenazine

Disease interactions

Psychiatric Conditions

Psychiatric conditions are disorders associated with mental health such as depression, anxiety, or schizophrenia. Corex DX Syrup should be used with caution in patients with psychiatric conditions due to an increased risk of confusion and hallucinations. Consult your doctor before taking this medicine if you are suffering from any such mental health conditions.

Asthma

Asthma is a condition of breathing difficulty due to the narrowing of the airway passage. Corex DX Syrup is not recommended for use if you have asthma due to the risk of worsening your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Use Corex DX Syrup as advised by your doctor. You may take this medicine with or without food. Never take more than the prescribed dose. Inform your doctor if you have stomach ulcers before taking Corex DX Syrup. Consult your doctor if you do not see any improvement even after 7 days of using this medicine. Keep away from the reach of children and pets. Do not use it after the expiry date. Ensure that unused medicine is disposed of properly. Do not give your medicine to other people even if their condition appears to be the same as yours.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Corex DX Syrup is a combination of chlorpheniramine and dextromethorphan. Dextromethorphan reduces the activity of the cough centre in the brain and thus helps in suppressing the cough. Chlorpheniramine works by stopping the action of a natural substance produced by the body called histamine which is responsible for causing allergic symptoms. Hence, this combination is effective for treating cough and associated allergic symptoms.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Upper respiratory combinations, Antitussives, Antihistamines

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Chlorpheniramine maleate. [online] Available at: < [Accessed 20 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/5281068>

Pubchem.ncbi.nlm.nih.gov. 2021. Delsym. [online] Available at: < [Accessed 20 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/5464025>

Drugs, H., 2021. Chlorpheniramine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < 20 August 2021].

https://medlineplus.gov/druginfo/meds/a682543.html>[Accessed

Drugs, H., 2021. Dextromethorphan: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 20 August 2021].

https://medlineplus.gov/druginfo/meds/a682492.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - COUGH AND COLD- chlorpheniramine maleate and dextromethorphan hydrobromide liquid. [online] Available at: < [Accessed 20 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=03401433-923e-4577-ba58-9087515c8053>
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Information on this page was last updated on 25 Aug 2021

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