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Cortel A (5/40 mg) Tablet
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Cortel A (5/40 mg) Tablet

Manufactured byCorona Remedies Pvt. Ltd.
ContainsAmlodipine (5 mg) + Telmisartan (40 mg)
Description
Cortel A (5/40 mg) Tablet is a combination of Amlodipine and Telmisartan. It is an anti-hypertensive medicine used for the treatment of high blood pressure. This medicine works by relaxing the blood vessels, making the blood flow easily, thus lowering blood pressure. This will reduce your risk of having a heart attack or a stroke by making it easier for your heart to pump blood around your body. Cortel A (5/40 mg) Tablet shows some common side effects like swelling in your ankles or feet, dizziness, back pain, headache, sleepiness, nausea, diarrhoea and stomach pain. Most of these are temporary and usually resolve with time. Cortel A (5/40 mg) Tablet is also known to cause sleepiness and dizziness, so you should not drive or do any activity that requires mental focus after taking medicine. Avoid consuming alcohol with this medicine as it can worsen dizziness. Cortel A (5/40 mg) Tablet can be taken with or without food. The dose will be decided by your doctor depending on your blood pressure levels. Avoid abrupt discontinuation of the treatment as your blood pressure may increase if you do so. Cortel A (5/40 mg) Tablet is not recommended for use if you are allergic to it. If you have any pre-existing kidney or liver problems, or other medical conditions, inform your doctor about them. Inform your doctor about all medicines and supplements you are taking as this medicine can interact with them and can cause side effects. Cortel A (5/40 mg) Tablet is not recommended for use in children below 18 years of age. Consult your doctor if you are pregnant, or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Cortel A (5/40 mg) Tablet

  • Swelling of ankles or feet
  • Difficulty in breathing
  • Dizziness
  • Back pain
  • Redness of face, neck, arms and chest
  • Muscle pain
  • Weakness
  • Stomach pain
  • Anxiety
  • Diarrhoea
  • Constipation
  • Sweating
  • Changes in vision
  • Difficulty or painful urination
  • Headache
  • Sleepiness
  • Nausea
  • Fast or pounding heartbeat

Uses of Cortel A (5/40 mg) Tablet

What is it prescribed for?

  • Essential hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    You may start to feel better in 1-2 hours after taking Cortel A (5/40 mg) Tablet.
  • How long do the effects of this medicine last?
    The effect of Cortel A (5/40 mg) Tablet lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Cortel A (5/40 mg) Tablet due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. Avoid performing activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Cortel A (5/40 mg) Tablet.
  • Can this medicine be taken during pregnancy?
    Cortel A (5/40 mg) Tablet should not be used by pregnant women as it may cause harm to the developing foetus. Consult you doctor if you are pregnant or planning a pregnancy.
  • Can this medicine be taken while breast-feeding?
    Cortel A (5/40 mg) Tablet is not recommended for use in breastfeeding women as may pass into breastmilk in some amounts. Consult your doctor if you are breastfeeding while taking this medicine.

Allergy

Avoid taking Cortel A (5/40 mg) Tablet if you have a known allergy to amlodipine, telmisartan or any other component of this medicine. This could lead to symptoms like skin rash, itching/swelling (especially of the face/tongue/throat), breathing difficulty, hives (painful eruptions that itch and sting), etc.

Aliskiren

Aliskiren is the first in a class of drugs called direct renin inhibitors used for the treatment of hypertension ( increase in blood pressure). Coadministration of aliskiren and Cortel A (5/40 mg) Tablet is not recommended as it may increase the risk of hyperkalaemia (high levels of potassium in your blood), which in severe cases can lead to kidney failure, muscle paralysis, irregular heart rhythm, and cardiac arrest. This risk is especially higher in people with diabetes and kidney problems.
Warnings for special population

Pregnancy

Cortel A (5/40 mg) Tablet should not be used by pregnant women as it may cause harm to the developing foetus. Consult you doctor if you are pregnant or planning a pregnancy.

Breast-feeding

Cortel A (5/40 mg) Tablet is not recommended for use in breastfeeding women as may pass into breastmilk in some amounts. Consult your doctor if you are breastfeeding while taking this medicine.
General warnings

Hypotension

Cortel A (5/40 mg) Tablet should be used with caution if you have aortic stenosis ( narrowing of the valve of the aorta, the largest artery to branch off from the heart). This medicine may decrease the functioning of the heart and lead to extremely low blood pressure and heartbeat.

Use in children

Cortel A (5/40 mg) Tablet is not recommended for use in children below 18 years of age since the safety and efficacy of the use of this medicine are not clinically established.

Hyperkalaemia

Hyperkalaemia (increase in the blood potassium levels) may occur after taking Cortel A (5/40 mg) Tablet. It may result in kidney failure, muscle paralysis, irregular heart rhythm, and cardiac arrest. It is important to maintain adequate fluid intake during treatment with this medicine

Renal artery stenosis

Renal artery stenosis is the narrowing of one or more arteries that carry blood to your kidneys. Cortel A (5/40 mg) Tablet should be used with caution if you have renal artery stenosis as this medicine will alter the flow of the blood in these blood vessels, which may lead to improper filtering of the blood. Your blood urea and serum creatinine levels will be closely monitored by your doctor.

Primary aldosteronism

Primary aldosteronism occurs when your adrenal glands produce too much of a hormone called aldosterone. This hormone regulates salt and water levels in the body. Cortel A (5/40 mg) Tablet is not recommended for use if you have primary hyperaldosteronism since it may affect the salt and water balance in your body and worsen your condition.

Driving and operating machines

Cortel A (5/40 mg) Tablet has a moderate effect on the ability to drive or use machines. If you experience side effects such as dizziness or drowsiness, avoid performing activities that require high mental alertness like driving or operating machines.

Liver impairment and biliary obstruction

Cortel A (5/40 mg) Tablet is not recommended for use if you have severe liver problems. This medicine is broken down and absorbed in the liver. If you take this medicine while you have pre-existing liver problems, it will worsen your condition further.

Kidney impairment

Cortel A (5/40 mg) Tablet should be used with caution if you have severe kidney problems. This medicine is filtered and excreted through the kidneys. Using this medicine while you have kidney problems will damage your kidneys and worsen your condition.

Missed Dose

If you forget to take the dose of Cortel A (5/40 mg) Tablet at a given time, then take it as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the dose prescribed by your doctor. If you have intentionally or accidentally consumed more than the prescribed amount of Cortel A (5/40 mg) Tablet, then you might feel headache, confusion, fever, change in the heartbeat, nausea, vomiting etc. Contact your doctor immediately for further guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Cortel A (5/40 mg) Tablet due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. Avoid performing activities that require high mental alertness such as driving vehicles or operating machines if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Carbamazepine

Itraconazole

Prednisolone

Rifampicin

Captopril

Insulin

Nonsteroidal anti-inflammatory medicines

Disease interactions

Cardiogenic shock

Cortel A (5/40 mg) Tablet is not recommended for use when you have cardiogenic shock (a life-threatening condition where your heart abruptly stops pumping blood). Using this medicine will further decrease your heart’s ability to pump blood and reduce your blood pressure and heart rate drastically. This can be fatal.

Congestive heart failure

Congestive heart failure is a chronic progressive condition that affects the pumping power of your heart muscle. Cortel A (5/40 mg) Tablet should be used with caution if you have congestive heart failure, as it will further reduce your heart’s ability to pump blood leading to very low blood pressure and slow heartbeat.

Coronary Artery Disease

Cortel A (5/40 mg) Tablet should be used with extreme caution if you have coronary artery diseases (a condition where the blood vessels of your heart are damaged, mainly due to build-up of plaque) as it may decrease your heart rate. If this medicine is prescribed in such conditions, close monitoring of the heart function is required. Your doctor will suggest tests to closely monitor your heart function while you are on this medication

Angioedema

Angioedema is the rapid swelling of the area beneath the skin because of fluid retention. Cortel A (5/40 mg) Tablet has to be used with caution as it may cause your body to retain excess water, which could lead to fluid retention and swelling in certain places like the face, eyes, lips, tongue or legs. Do not use the medicine if you have a history of angioedema related to previous therapy or if you have hereditary angioedema. Inform your doctor about such conditions.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with Cortel A (5/40 mg) Tablet as it can increase the absorption of this medicine. This could lead to excessive lowering of blood pressure or worsen side effects.
Using Cortel A (5/40 mg) Tablet together with multivitamins containing minerals may decrease the effects of this medicine. Take these two medicines with at least a 2-hour interval Avoid a high potassium diet or supplements containing potassium during treatment with Cortel A (5/40 mg) Tablet. It can cause an increase in the potassium level in your blood leading to symptoms such as weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs.
Avoid a high potassium diet or supplements during treatment with Cortel A (5/40 mg) Tablet. It can cause increase in the potassium level in your blood leading to symptoms such as weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Your doctor/dietitian will suggest an appropriate diet for you to avoid a high intake of potassium.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Cortel A (5/40 mg) Tablet may be taken with or without food. Swallow the tablet whole with a sufficient amount of water. Do not crush, break or chew the tablet. The dose prescribed is based on your situation thus, avoid taking more or less dose than that prescribed by your doctor. You should not stop taking the medicine abruptly without your doctor's consultation as it can cause withdrawal symptoms. You should follow a balanced diet and exercise regularly to get the maximum benefit from the treatment. Avoid taking potassium-rich food as it may increase your potassium level in the blood. Also, avoid taking grapefruit juice with Cortel A (5/40 mg) Tablet as it can increase the level of this medicine in your blood. Be careful while standing up from sitting or lying down position as this medicine may cause a sudden drop in your blood pressure which can make you dizzy. Cortel A (5/40 mg) Tablet can cause swelling in your ankles and feet so try raising your legs when you are sitting. Consult your doctor if the swelling worries you. This medicine can cause sleepiness and dizziness so try to avoid activities that require mental focus, especially at the start of the treatment or until you know how this medicine will affect you.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Cortel A (5/40 mg) Tablet is a combination of amlodipine and telmisartan. Both the medicine works differently to relax the blood vessels and improve blood flow. Thus, this combination is effective in reducing blood pressure. It is used when a single medicine is not sufficient to control your blood pressure.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Angiotensin II inhibitors with calcium channel blockers, Antihypertensive combinations

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - TELMISARTAN AND AMLODIPINE tablet. [online] Available at: < [Accessed 14 July 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=15b438b4-4874-43f4-a50a-4e6f3e5530ac>

Ema.europa.eu. 2021. [online] Available at: < [Accessed 14 July 2021].

http://www.ema.europa.eu/docs/en_GB/document_library/EPAR_-_Product_Information/human/001224/WC500098190.pdf>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 14 July 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/022401lbl.pdf>

Dailymed.nlm.nih.gov. 2021. These highlights do not include all the information needed to use AMLODIPINE BESYLATE TABLETS safely and effectively. See full prescribing information for AMLODIPINE BESYLATE TABLETS. AMLODIPINE BESYLATE Tablets for oral administration Initial U.S. Approval: 1992. [online] Available at: < [Accessed 14 July 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1cec7a02-b7a5-49e1-ab64-3a4dab4149d2>
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Information on this page was last updated on 9 Sep 2021

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