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Deriphyllin Retard 300 Tablet
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Deriphyllin Retard 300 Tablet

Manufactured byZydus Cadila
ContainsEtofylline (231 mg) + Theophylline (69 mg)
Description
Deriphyllin Retard 300 Tablet is a combination medicine used to prevent and treat wheezing, shortness of breath, chest tightness associated with lung diseases like asthma, chronic bronchitis, emphysema, chronic obstructive pulmonary disorder (COPD), etc.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Deriphyllin Retard 300 Tablet

  • Increased/Irregular heart rate
  • Convulsions (seizures)
  • Allergic skin reaction
  • Stomach discomfort and pain
  • Diarrhea
  • Headache
  • Sleeplessness
  • Swelling of ankles or feet
  • Yellowing of skin and eyes
  • Increased urination frequency
  • Twitching and unusual movement of muscles
  • Elevated liver enzymes

Uses of Deriphyllin Retard 300 Tablet

What is it prescribed for?

  • Bronchospasm
  • Chronic obstructive pulmonary disease (COPD)
  • Asthma
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to theophylline, etofylline, any medicine belonging to the xanthine derivative group, or any other inactive ingredients present along with these medicines.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other diseases

Report the instance of any disease of the heart and blood vessels, brain, thyroid glands etc to the doctor before receiving this medicine. This medicine should be used with caution and any disease worsening symptom should be reported to the doctor immediately. An alternative treatment option should be considered in some cases based on the clinical condition.

Other medicines

Deriphyllin Retard 300 Tablet may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Smoking

This medicine tends to be less effective if you smoke or consume tobacco products. Avoid or limit the uptake of tobacco products while taking this medicine.

Caffeine

Consumption of caffeine while taking this medicine may cause certain side effects to appear. Avoid or limit the uptake of caffeine or caffeine products while taking this medicine.

Fever

This medicine should be used with caution if you have a high fever (febrile) with a headache, chills, and joint pain. Report any such instance to the doctor while taking this medicine.

Theophylline toxicity

Use of high doses of this medicine has been associated with toxicity due to an accumulation of the medicine in the body after long term use. It is advised to measure the serum levels and withhold the dose of this medicine if toxicity symptoms are developed.

Use in the elderly

This medicine should be used with caution in the elderly as the risk of adverse effects are significantly higher.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Fluvoxamine

Lithium

Phenytoin

Propranolol

Ethinyl Estradiol

Cimetidine

Ciprofloxacin

Azithromycin

Riociguat

Disease interactions

Peptic ulcer

This medicine should be administered with caution in patients with active peptic ulcer disease as the risk of worsening of symptoms is very high. Report any unusual symptoms to the doctor on priority. Appropriate dose adjustment or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients who are suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with caution in patients who are suffering from seizures due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Heart rhythm disorders

This medicine should be used with caution in a patient suffering from a heart rhythm disorder due to the increased risk of worsening of the patient's condition. Suitable clinical investigations should be performed to determine the safe and effective use of this medicine. An alternative treatment option should be considered in some cases based on the clinical condition.
Food interactions
Avoid or limit the uptake of caffeine while taking this medicine due to the increased risk of adverse effects. Report any incidence of unusual symptoms to the doctor on priority.
Avoid the consumption of tobacco and marijuana while taking this medicine. The risk of adverse effects is high even with secondhand smoking.
Lab interactions

Serum Uric acid test

Use of this medicine may give a false-positive result for this test. It is advised to inform the doctor and lab technician about the consumption of this medicine before the test is performed.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine as instructed by the doctor. You should adhere to any dose changes instituted by the doctor over the course of treatment. Do not take this medicine in larger or smaller quantities than prescribed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the muscles of the airways in the lungs. It also reduces the sensitivity of lungs to allergens that cause irritation and constriction of muscles in the chest and the lungs.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Methylxanthines, Antiasthmatic combinations

Schedule

Schedule H

Theophylline - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00277

DailyMed - Theophylline tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1f2a4716-34fe-4a2c-8bbf-5ed16772a967

Theophylline | C7H8N4O2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/2153#section=Top

Etofylline [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 4 March 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/etofylline#
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Information on this page was last updated on 4 Mar 2019

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