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Dermi 5 Cream
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Dermi 5 Cream

Manufactured byUniversal Twin Labs
ContainsClobetasol (0.05 %w/w) + Gentamicin (0.1 %w/w) + Tolnaftate (1 %w/w) + Cliquinol (1 %w/w) + Ketoconazole (2 %w/w)
Description
Dermi 5 Cream is a combination of Clobetasol, Gentamicin, Tolnaftate, Cliquinol and Ketaconazole. It is a topical medicine (to be applied externally), that helps to treat skin infections caused by bacteria and fungi. This cream works by killing bacteria and fungi, thereby reducing skin infections. Dermi 5 Cream may cause side effects like burning, irritation, itching, and redness at the site of application. Inform your doctor if these side effects bother you or persist for a longer duration. However, this cream is banned for use in India due to its severe side effects. Avoid using this cream if you are allergic to it. Dermi 5 Cream is a prescription medicine and should be applied as directed by your doctor. Wash and dry the affected area before application. Apply a small amount of Dermi 5 Cream to the affected area 1-2 times a day. Do not touch or scratch the affected area as it may spread the infection. Dermi 5 Cream is for external use. Avoid contact with your eyes and mouth. Wash your eyes and mouth immediately in case of accidental contact. If you are pregnant or breastfeeding, consult your doctor before using this cream. It may take several weeks for this medicine to improve your condition. Hence, do not stop using it without consulting your doctor. Dermi 5 Cream is not recommended for use in children below 12 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Dermi 5 Cream

  • Burning sensation of skin
  • Dry or scaly skin
  • Redness of skin
  • Skin irritation
  • Itching of skin

Uses of Dermi 5 Cream

What is it prescribed for?

  • Bacterial skin infections
  • Fungal skin infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Dermi 5 Cream shows its effect within 1-2 hours after application.
  • How long do the effects of this medicine last?
    The duration for which Dermi 5 Cream remains active in the body is 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Dermi 5 Cream.
  • Can this medicine be taken during pregnancy?
    Dermi 5 Cream is a topical preparation. If you are pregnant, use this cream only if prescribed by your doctor.
  • Can this medicine be taken while breast-feeding?
    Application of Dermi 5 Cream to the nipple may increase the risk of diarrhoea in the infant. Consult your doctor before using it during breastfeeding.

Allergy

Avoid using Dermi 5 Cream if you are allergic to it. Seek medical attention immediately if you notice symptoms such as a skin rash, itching/swelling anywhere on your body, dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Dermi 5 Cream is a topical preparation. If you are pregnant, use this cream only if prescribed by your doctor.

Breast-feeding

Application of Dermi 5 Cream to the nipple may increase the risk of diarrhoea in the infant. Consult your doctor before using it during breastfeeding.
General warnings

Use in Children

Dermi 5 Cream is not recommended for use in children below 12 years of age since the safety and efficacy data is not available.

Other medicines

Inform your doctor about all your current medicines as Dermi 5 Cream may interact with the medicines and cause side effects.

For external use only

Dermi 5 Cream is recommended for external use only. Avoid contact with the eyes, mucous membranes, or open wounds.

Allergic reactions

Dermi 5 Cream may rarely cause an allergic reaction in the body. Any instance indicative of allergic reactions should be reported to your doctor immediately.

Missed Dose

Apply the missed dose of Dermi 5 Cream as soon as you remember. Do not apply twice to compensate for the missed dose.

Overdose

An overdose of Dermi 5 Cream is not likely to cause severe symptoms. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Dermi 5 Cream is used in treating bacterial and fungal skin infections. Apply a thin layer of the cream to the affected area as instructed by the doctor. Dermi 5 Cream is an external preparation, therefore contact with the mouth, eyes, nose, ears should be avoided. In case of accidental contact, wash the parts with water thoroughly. Dermi 5 Cream may take several weeks to show its action. Finish the entire course of treatment even if your symptoms begin to clear up after a few days. Avoid scratching or pricking the affected area as it can worsen the infection. Ensure that unused medicine is disposed of properly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Dermi 5 Cream is a combination of five medicines- Clobetasol, Gentamicin, Clioquinol (Iodochlorhydroxyquin), Ketoconazole, and Tolnaftate. Clobetasol works by inhibiting the production of chemicals that cause inflammation. Gentamicin works by preventing the formation of the bacterial cell wall. Tolnaftate shows its antifungal activity by inhibiting the growth of the fungal cell membrane. Clioquinol work by inhibiting the DNA synthesis of the bacterial cell membrane. Ketoconazole works by stopping the growth of fungi by disrupting the cell wall of the fungi.
Legal Status

Banned

Unknown

Unknown

Unknown

Classification

Category

Topical antifungals, Topical anti-infectives, Topical antibiotics

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Tolnaftate. [online] Available at: < [Accessed 31 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Tolnaftate>

Pubchem.ncbi.nlm.nih.gov. 2021. Clioquinol. [online] Available at: < [Accessed 31 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clioquinol>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 13 January 2021]

https://www.medicines.org.uk/emc/files/pil.970.pdf>

Drugs, H., 2021. Clobetasol Topical: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 30 March 2021].

https://medlineplus.gov/druginfo/meds/a686008.html>

Dailymed.nlm.nih.gov. 2021. DailyMed - GENTAMICIN SULFATE- gentamicin sulfate cream. [online] Available at: < [Accessed 19 February 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9e550dc9-509e-da05-8a97-ecbd0f5dd633>

Anséhn, S. and Nilsson, L. (1984). Direct membrane-damaging effect of ketoconazole and tioconazole on Candida albicans demonstrated by bioluminescent assay of ATP. Antimicrobial Agents and Chemotherapy, [online] 26(1), pp.22–25. Available at: [Accessed 29 Jul. 2021]. ‌

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC179909/
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Information on this page was last updated on 10 Jan 2022

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