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Dubagest 8 % Gel
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Dubagest 8 % Gel

Manufactured byGlenmark Pharmaceuticals Ltd.
ContainsNatural Micronised Progesterone
Description
Dubagest 8 % Gel has a similar action to the female hormone (chemical messenger) progesterone. It is used to treat various problems related to hormonal imbalance in the body, such as secondary amenorrhea (absence of three or more periods in a row) and infertility in women. Dubagest 8 % Gel has some side effects like stomach pain and discomfort, drowsiness, breast pain and tenderness, vaginal irritation, etc. These side effects are mild and may subside by themselves. However, consult your doctor if they bother you for a longer time or worsen. Dubagest 8 % Gel should be used as instructed by your doctor. Avoid using more than the recommended dose. Use it every day at the same time for the ease of remembering. Your doctor may recommend that you continue using this medicine for a certain time after you get pregnant, as it will help to support your new pregnancy. Dubagest 8 % Gel is not recommended for use if you are allergic to it. Inform your doctor if you have vaginal bleeding, kidney, liver, or heart problems, or any other medical conditions. Also, inform about all your current medications to avoid undesired effects. Dubagest 8 % Gel is not indicated for use in children. This medicine may be used during pregnancy upon your doctor's recommendation.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Dubagest 8 % Gel

Crinone 8 % Gel
Serum Institute Of India Ltd.
Naturogest 8 % Gel
Zydus Cadila
Prostagen 8 % Gel
Unichem Laboratories Ltd.
Susten 8 % Gel
Sun Pharma Laboratories Ltd.

Side effects

Major & minor side effects for Dubagest 8 % Gel

  • Vaginal discharge
  • Vaginal bleeding
  • Vaginal itching
  • Rash
  • Vaginal irritation
  • Nausea
  • Headache
  • Abdominal pain and discomfort
  • Drowsiness

Uses of Dubagest 8 % Gel

What is it prescribed for?

  • Female infertility
  • Secondary Amenorrhoea
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Dubagest 8 % Gel to show its effect is not clinically established.
  • How long do the effects of this medicine last?
    The time duration for which Dubagest 8 % Gel remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Dubagest 8 % Gel.
  • Can this medicine be taken during pregnancy?
    Dubagest 8 % Gel is recommended for use during pregnancy only upon your doctor's recommendation. Consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Dubagest 8 % Gel is not recommended for use while breastfeeding unless necessary. Consult your doctor before using this medicine.

Allergy

Avoid using Dubagest 8 % Gel if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Abnormal vaginal bleeding

Avoid using Dubagest 8 % Gel if you have abnormal vaginal bleeding that has not been diagnosed, as it may worsen your condition.

Breast cancer

Avoid using Dubagest 8 % Gel if you have or are suspected of having breast cancer. Also, inform your doctor if you have a family history of breast cancer.

Miscarriage

Avoid using Dubagest 8 % Gel if you have a missed abortion (when the foetus has died in the womb during pregnancy, however, the body has not yet recognised it and expelled from the body) or ectopic pregnancy (a fertilized egg grows outside a woman's uterus).

Heart and blood vessel disorder

Avoid using Dubagest 8 % Gel if you recently have had a stroke (brain damage due to interrupted blood supply to the brain), heart attack, or blood clot disorder, as it may worsen your condition.

Liver disease

Avoid using Dubagest 8 % Gel if you have liver problems due to the increased risk of liver injury.
Warnings for special population

Pregnancy

Dubagest 8 % Gel is recommended for use during pregnancy only upon your doctor's recommendation. Consult your doctor before using this medicine.

Breast-feeding

Dubagest 8 % Gel is not recommended for use while breastfeeding unless necessary. Consult your doctor before using this medicine.
General warnings

Diabetes

Dubagest 8 % Gel may alter blood sugar levels. Hence, it should be used with caution if you have diabetes (high blood sugar levels).

Other medicines

Dubagest 8 % Gel may interact with other medicines and cause undesired effects. Hence, inform your doctor about all your current medications before starting the treatment to avoid interaction. It is not recommended for use with other vaginal products, as it may alter the release and absorption of this medicine, thus reducing its effectiveness.

Fluid Retention

Oedema refers to the accumulation of fluid in the body tissues causing swelling, especially in the legs and feet. Dubagest 8 % Gel may cause fluid retention, particularly when used in high doses for a prolonged time. Hence, it should be used with caution if you have heart or kidney problems, as it may further worsen your condition.

Missed Dose

Apply the missed dose of Dubagest 8 % Gel as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never apply more than the prescribed quantity of Dubagest 8 % Gel. Seek emergency medical attention if an overdose with this medicine is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Carbamazepine

Ketoconazole

Insulin

Phenobarbital

Fluconazole

Disease interactions

Depression

Dubagest 8 % Gel should be used with caution if you have depression as it may further worsen your condition.

Retinal thrombosis

Retinal thrombosis is an eye condition that occurs due to blood clot formation in the vein in the retina (part of the eye that enables vision). It is a painless condition that causes blurring of vision or loss of eyesight, especially in one eye. Dubagest 8 % Gel should be used with caution if you have eye problems, as it may cause retinal thrombosis and further worsen your condition.
Food interactions
Information not available.
Lab interactions

Blood coagulation tests

Report the use of Dubagest 8 % Gel to your doctor before undergoing a test to measure the coagulation (blood clot) time. The use of this medicine may interfere with the test results.

Thyroid function tests

Dubagest 8 % Gel is known to give a false-positive result for thyroid function tests. Hence, inform the lab technician or your doctor about the use of this medicine before undergoing the lab test.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Use Dubagest 8 % Gel in the dose and duration prescribed by your doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not use in larger or smaller quantities than recommended. Ensure that the treatment is completed. Do not stop the use of this medicine without consulting your doctor. Regular follow-up visits with your doctor and breast examination are necessary during treatment with this medicine to observe the presence of lumps in the breast.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Dubagest 8 % Gel acts by maintaining the levels of progesterone hormone and creating an environment that allows a fertilized egg to adhere to the wall of the uterus (womb). This helps you to get pregnant. It also helps in maintaining a regular menstrual cycle. This helps in treating menstrual disorders.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Progestins, Sex hormones

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Progesterone. [online] Available at: < [Accessed 5 November 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Progesterone>

Medicines.org.uk. 2021. Cyclogest 400mg pessaries - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 5 November 2021].

https://www.medicines.org.uk/emc/product/5569/smpc#INDICATIONS>

Dailymed.nlm.nih.gov. 2021. DailyMed - CRINONE- progesterone gel. [online] Available at: < [Accessed 5 November 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2c8ffbd2-6b7a-42c7-b29e-e4de69dad9e6>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 5 November 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022057s001lbl.pdf>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 5 November 2021].

https://www.medicines.org.uk/emc/files/pil.1283.pdf>
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Information on this page was last updated on 25 Feb 2022

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