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Duzela 40 MG Capsule
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Duzela 40 MG Capsule

Manufactured bySun Pharma Laboratories Ltd.
ContainsDuloxetine
Description
Duzela 40 MG Capsule is an antidepressant medicine. It is used to treat depression and other mood disorders such as anxiety. It is also used to treat diabetic neuropathic pain (nerve damage due to high blood sugar levels) and fibromyalgia (widespread pain in the body). It works by increasing the level of chemical substances (serotonin and norepinephrine) in the brain that help maintain mental balance and stop the movement of pain signals in the brain. Duzela 40 MG Capsule can show side effects like nausea, dry mouth, heartburn, increased sweating, etc. These side effects subside on their own. However, consult your doctor if they are bothering you for a longer time or getting persistent. Avoid driving vehicles or operating machines as this medicine can make you feel drowsy or dizzy. Duzela 40 MG Capsule may be taken with or without food. Your doctor will determine the dose and duration of treatment based on the severity of your condition. Take it at the same time every day to maintain a constant level of medicine in your body and for ease of remembering. Do not stop taking this medicine without consulting your doctor as it can cause withdrawal symptoms such as anxiety, tremor, headache, irritability, dizziness, etc. Duzela 40 MG Capsule can alter your mood and cause suicidal thoughts. Therefore, closely observe for any changes in your mood while you take this medicine. Also, inform your doctor about your current medications and existing medical conditions to avoid any side effects. If you are pregnant or breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Duzela 40 MG Capsule

Dulane 40 MG Capsule
Sun Pharma Laboratories Ltd.
Duleve 40 MG Capsule
Zydus Cadila
Dulot 40 MG Capsule
Lupin Ltd.
Dutin 40 MG Capsule
Ranbaxy Laboratories Ltd.
Duzac 40 MG Capsule
Cipla Ltd.

Side effects

Major & minor side effects for Duzela 40 MG Capsule

  • Nausea
  • Sleepiness
  • Dry mouth
  • Body pain
  • Abnormal ejaculation
  • Loose stools
  • Shaking of hands or feet
  • Heartburn

Uses of Duzela 40 MG Capsule

What is it prescribed for?

  • Major depressive disorder
  • Generalized anxiety disorder
  • Diabetic Peripheral Neuropathy
  • Chronic Musculoskeletal Pain
  • Fibromyalgia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Duzela 40 MG Capsule can be seen in 2 hours.
  • How long do the effects of this medicine last?
    The time duration for which Duzela 40 MG Capsule remains active in the body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during the treatment with Duzela 40 MG Capsule due to the increased risk of liver injury.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Duzela 40 MG Capsule.
  • Can this medicine be taken during pregnancy?
    Duzela 40 MG Capsule is not recommended for use in pregnancy as this medicine may affect your developing foetus. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Duzela 40 MG Capsule may pass into breastmilk in small amounts. Hence consult your doctor before taking this medicine if you are breastfeeding.

Allergy

Duzela 40 MG Capsule is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Monoamine oxidase inhibitors

MAOIs (monoamine oxidase inhibitors) are medications used to treat depression and other mental health conditions. Do not take Duzela 40 MG Capsule with MAOIs or within two weeks after discontinuing MAOIs, as it can lead to life-threatening complications.

Narrow angle glaucoma

Narrow-angle glaucoma is a condition in which pressure inside your eyes increases. It happens due to fluid build-up caused by blocked drainage canals. Duzela 40 MG Capsule is not recommended if you have narrow-angle glaucoma as it may increase the risk of mydriasis (a condition in which the pupil of the eye gets widened due to increased eye pressure).
Warnings for special population

Pregnancy

Duzela 40 MG Capsule is not recommended for use in pregnancy as this medicine may affect your developing foetus. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

Duzela 40 MG Capsule may pass into breastmilk in small amounts. Hence consult your doctor before taking this medicine if you are breastfeeding.
General warnings

Suicidal thoughts

Duzela 40 MG Capsule should be used with caution due to the increased risk of suicidal tendencies. Any mood change should be closely monitored.

Orthostatic Hypotension and fall

Duzela 40 MG Capsule is known to cause orthostatic hypotension (sudden drop in blood pressure when you stand up from a sitting or lying position), especially during the first week of the treatment. Inform your doctor if you experience dizziness or unsteady walking while taking this medicine.

Abnormal bleeding

Duzela 40 MG Capsule may increase the risk of bleeding, especially if you are taking blood thinner medicines. Inform your doctor about your current medications to avoid such side effects.

Low sodium levels

Duzela 40 MG Capsule should be used with caution as it may lower sodium levels in the body. Inform your doctor if you experience any symptoms of unsteadiness, headache, confusion, loss of energy, difficulty in concentration, etc. while taking this medicine.

Withdrawal symptoms

Abrupt discontinuation of Duzela 40 MG Capsule may increase the risk of side effects, especially if you have been using a high dose for a long duration. Your doctor may suggest a gradual dose reduction over a period to avoid any undesired effect. Hence do not stop the use of this medicine without consulting your doctor.

Skin reactions

Duzela 40 MG Capsule may cause rare but serious skin reactions in some cases. Consult your doctor if you experience symptoms like itching, peeling of skin, or rashes.

Kidney/Liver Diseases

Duzela 40 MG Capsule should be used with caution if you have liver or kidney problems as it may worsen your condition.

Driving or operating machines

Duzela 40 MG Capsule may cause drowsiness or dizziness in some people. It is advised that you avoid performing activities that require mental alertness, such as driving vehicles or operating machines, if you experience such symptoms during treatment with this medicine.

Missed Dose

Take the missed dose of Duzela 40 MG Capsule as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Do not take more than the prescribed dose of this medicine. Seek emergency medical treatment in case of an overdose of Duzela 40 MG Capsule.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during the treatment with Duzela 40 MG Capsule due to the increased risk of liver injury.
Interaction with Medicine

Ciprofloxacin

Aspirin

Diuretics

Dextromethorphan

Disease interactions

Diabetes

Duzela 40 MG Capsule should be used with caution if you have diabetes (high blood sugar levels) due to the increased risk of alteration in blood sugar levels. Monitor your blood sugar levels regularly while you are taking this medicine.

Glaucoma

Glaucoma is a group of eye conditions that may occur due to increased fluid pressure within the eyes. Duzela 40 MG Capsule should be used with caution if you have glaucoma due to the risk of an increase in the fluid pressure in the eye. Your doctor may adjust your dose or suggest another medicine in such cases.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Duzela 40 MG Capsule as instructed by your doctor. Do not crush, break, or chew the capsule. It may be taken with or without food. Avoid taking this medicine in larger amounts than prescribed. Consult the doctor if you experience any undesirable effects that persist or worsen. Duzela 40 MG Capsule is given for the long term. Therefore, take it for the recommended duration for maximum benefits. Keep Duzela 40 MG Capsule away from children and pets. Throw away the unused medicine safely after the expiry date.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Duzela 40 MG Capsule works by increasing the levels of certain chemical substances in the brain. Thus it helps in maintaining mental balance and also blocking the movement of pain signals in the brain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Serotonin-norepinephrine reuptake inhibitors

Schedule

Schedule H

Drugs, H., 2021. Duloxetine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 24 December 2021].

https://medlineplus.gov/druginfo/meds/a604030.html#overdose

Pubchem.ncbi.nlm.nih.gov. 2021. Duloxetine. [online] Available at: [Accessed 24 December 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/duloxetine

Medicines.org.uk. 2022. Duloxetine Dr. Reddys 60 mg Gastro-Resistant Capsules, Hard - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: [Accessed 14 July 2022].

https://www.medicines.org.uk/emc/product/6966/smpc
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Information on this page was last updated on 7 Sep 2022

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