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Febrex 650 MG Tablet
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Febrex 650 MG Tablet

Manufactured byIndoco Remedies Ltd.
ContainsParacetamol
Description
Febrex 650 MG Tablet is the most widely used over-the-counter (OTC) medication. It is used for the treatment of fever. It also provides relief from headache, toothache, backache, nerve pain, musculoskeletal pain, etc. associated with/without fever. Febrex 650 MG Tablet works by decreasing the intensity of pain signals to the brain. It also prevents the release of prostaglandins, the chemical that causes pain and an increase in body temperature. Febrex 650 MG Tablet is safe to use within the recommended dosage. However, in some cases, you may experience side effects such as nausea, vomiting, indigestion, diarrhoea, stomach pain, etc. Consult your doctor if these symptoms stay for a long time or if they become severe. Febrex 650 MG Tablet can be taken with or without food. If your doctor has prescribed this medicine, take it for the recommended duration. Never take more than the prescribed dose, or for a longer duration. Febrex 650 MG Tablet is not recommended if you are allergic to it. Inform your doctor if you have liver or kidney problems before taking this medicine. Though this medicine is safe for use in pregnancy and breastfeeding, it is recommended to consult your doctor before taking it.
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Substitutes

List of substitutes for Febrex 650 MG Tablet

Malidens 650 MG Tablet
Abbott Healthcare Pvt. Ltd.
Pacimol 650 MG Tablet
Ipca Laboratories Pvt. Ltd.
Paracetamol 650 MG Tablet
Novartis India Ltd.
Sumo L 650 Tablet
Alkem Laboratories Ltd.
Paragreat 650 Tablet
Mankind Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Febrex 650 MG Tablet

  • Nausea and Vomiting
  • Stomach pain
  • Diarrhoea
  • Indigestion
  • Skin Rash

Uses of Febrex 650 MG Tablet

What is it prescribed for?

  • Fever
  • Mild to Moderate pain
  • Post Vaccination Fever
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Febrex 650 MG Tablet shows its effect within 30-60 minutes after administration.
  • How long do the effects of this medicine last?
    The effect of Febrex 650 MG Tablet lasts for an average duration of 4 to 6 hours after administration.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Febrex 650 MG Tablet as it may cause liver damage. Consult your doctor immediately if you experience any signs and symptoms of liver injury like fever, rash, nausea, vomiting, fatigue, dark urine, jaundice, etc.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported with Febrex 650 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Febrex 650 MG Tablet may be used during pregnancy for the shortest time possible and the lowest effective dose. However, it is recommend to use this medicine after consultation with your doctor.
  • Can this medicine be taken while breast-feeding?
    Febrex 650 MG Tablet is considered safe during breastfeeding. It passes into the breastmilk in very small amounts which are not known to harm your baby. However, it is recommend to use this medicine after consultation with your doctor.

Allergy

Avoid taking Febrex 650 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, swelling and/or itching (especially on the face, lips, throat, etc.), dizziness, breathing difficulty, etc. after taking this medicine.

Kidney damage

Analgesic Nephropathy is a condition that causes kidney damage due to the long-term use of pain-relievers. Febrex 650 MG Tablet is not recommended for use if you have kidney problems associated with excessive use of painkillers.

Severe liver impairment

Febrex 650 MG Tablet gets converted to its active form in the liver. This medicine is not recommended if you have severe liver problems as it may cause further damage to your liver.
Warnings for special population

Pregnancy

Febrex 650 MG Tablet may be used during pregnancy for the shortest time possible and the lowest effective dose. However, it is recommend to use this medicine after consultation with your doctor.

Breast-feeding

Febrex 650 MG Tablet is considered safe during breastfeeding. It passes into the breastmilk in very small amounts which are not known to harm your baby. However, it is recommend to use this medicine after consultation with your doctor.
General warnings

Overdose and/or excessive use

Paracetamol poisoning is caused by the excessive use of Febrex 650 MG Tablet accidentally or intentionally, resulting in liver damage. Use this medicine as advised by your doctor/pharmacist. Seek emergency medical attention if an overdose is suspected.

Chronic malnutrition

Febrex 650 MG Tablet should be used with extreme caution if you are malnourished (lack of proper nutrition in the body) as it may increase the risk of side effects. Your doctor may recommend dose adjustments based on your body weight.

Kidney Diseases

Febrex 650 MG Tablet should be used with caution if you have kidney problems as it may increase the risk of side effects. Your doctor may suggest tests to closely monitor your kidney function during treatment with this medicine.

Use in children

Febrex 650 MG Tablet is not recommended for use in children below 10 years of age.

Missed Dose

Febrex 650 MG Tablet is normally taken on a needed basis. If you miss a scheduled dose take it as soon as possible but do not double the dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek immediate medical attention in case of an overdose with Febrex 650 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Febrex 650 MG Tablet as it may cause liver damage. Consult your doctor immediately if you experience any signs and symptoms of liver injury like fever, rash, nausea, vomiting, fatigue, dark urine, jaundice, etc.
Interaction with Medicine

Carbamazepine

Leflunomide

Phenytoin

Disease interactions

Liver Disease

Febrex 650 MG Tablet should be used with caution if you have liver problems as it may further increase the risk of liver damage. Inform your doctor before starting therapy with this medication. Your liver functions may be closely monitored by your doctor. Your doctor may recommend appropriate dose adjustments based on your clinical condition.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

Febrex 650 MG Tablet may interfere with the urine test and give a false positive result. Inform your doctor and/or lab technician about the use of this medicine before the test is performed.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Febrex 650 MG Tablet can be taken with or without food. Avoid taking more than the recommended dose or for a longer duration. Avoid consumption of alcohol while taking this medicine as it may increase the risk of liver damage. Inform your doctor if you are taking any other paracetamol-containing medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Febrex 650 MG Tablet decreases the intensity of pain signals to the brain. It also stops the release of prostaglandins, the chemical responsible for pain and increase in body temperature. Thus, this medicine provides relief from fever and mild to moderate pain.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Analgesics/Antipyretic

Schedule

OTC

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Pubchem.ncbi.nlm.nih.gov. 2020. Acetaminophen. [online] Available at: < [Accessed 21 December 2020].

https://pubchem.ncbi.nlm.nih.gov/compound/1983>

Drugs, H., 2020. Acetaminophen: Medlineplus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 21 December 2020].

https://medlineplus.gov/druginfo/meds/a681004.html>

Dailymed.nlm.nih.gov. 2020. Dailymed - 7 SELECT ACETAMINOPHEN- Acetaminophen Tablet. [online] Available at: < [Accessed 21 December 2020].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=168da31e-de62-4280-9c66-2b41d2d93c31>

Medicines.org.uk. 2020. Paracetamol 500Mg Tablets - Summary Of Product Characteristics (Smpc) - (Emc). [online] Available at: < [Accessed 29 December 2020].

https://www.medicines.org.uk/emc/product/5164/smpc>
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Information on this page was last updated on 8 Sep 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.