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Glup 500 MG Tablet
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Glup 500 MG Tablet

Manufactured byStrides Shasun Ltd.
ContainsMetformin
Description
Glup 500 MG Tablet is a medicine used to control high blood sugar levels. It is the first preferred medicine effectively used in people with type II diabetes (a condition where your body cannot produce sufficient insulin or resists insulin). Glup 500 MG Tablet helps in insulin production, which in turn reduces the excess blood sugar levels in your body. It also helps in minimizing the risk of diabetes-associated complications such as blindness, kidney damage, stroke (decreased blood flow to your brain), and heart attack. Regular monitoring of blood sugar levels is necessary while taking this tablet. Glup 500 MG Tablet may cause side effects like headache, nausea, diarrhoea, stomach pain, reduced blood sugar levels, weight gain, etc. Do not take this medicine if you are allergic to it. Alcohol intake can also cause reduced blood sugar levels. You may feel tired or uneasy during the treatment at the initial stages, hence avoid driving vehicles or operating machines. Glup 500 MG Tablet can be taken with food for better absorption. For the ease of remembering, take this tablet around the same time every day. Avoid taking Glup 500 MG Tablet for a long period unless prescribed by your physician as it may cause severe side effects. Inform your doctor if you are pregnant or breastfeeding before using this medicine.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Glup 500 MG Tablet

D Met 500 MG Tablet
Strides Shasun Ltd.
Eumet 500 MG Tablet
Cadila Pharmaceuticals Ltd.
Minimet 500 MG Tablet
Micro Labs Ltd.
X-Met 500 MG Tablet
Glenmark Pharmaceuticals Ltd.
Almetfor 500 mg Tablet
Alkem Laboratories Ltd.

Side effects

Major & minor side effects for Glup 500 MG Tablet

  • Nausea and vomiting
  • Diarrhoea
  • Abdominal pain
  • Loss of appetite
  • Weakness
  • Chest discomfort
  • Headache
  • Runny Nose
  • Heartburn
  • Swollen joints

Uses of Glup 500 MG Tablet

What is it prescribed for?

  • Type II Diabetes Mellitus
  • Polycystic Ovary Syndrome
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Glup 500 MG Tablet can be observed within three hours of intake.
  • How long do the effects of this medicine last?
    The duration for which Glup 500 MG Tablet shows its effect in your body is eight hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol should be avoided while treatment with Glup 500 MG Tablet due to severe side effects like reduced blood sugar levels, dizziness etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Glup 500 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Use of Glup 500 MG Tablet should be avoided during pregnancy as it may affect the foetus. Hence your physician may advise a safer alternative with the same therapeutic effect based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    It is not known whether Glup 500 MG Tablet passes into breast milk. Hence is not recommended for use during breastfeeding. Your physician may advise a safer alternative with the same therapeutic effect based on your clinical condition.

Allergy

Avoid taking Glup 500 MG Tablet or any other formulation containing it if you are allergic to it. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulties, etc.

Metabolic Acidosis

Glup 500 MG Tablet should be avoided for use if you have metabolic acidosis (electrolyte disorder with altered acid-base balance in your body) since it may worsen your condition.

Severe kidney impairment

Do not take Glup 500 MG Tablet if you have severe kidney impairment with changes in serum creatinine levels or abnormal creatinine clearance as it may worsen your health condition due to severe side effects.
Warnings for special population

Pregnancy

Use of Glup 500 MG Tablet should be avoided during pregnancy as it may affect the foetus. Hence your physician may advise a safer alternative with the same therapeutic effect based on your clinical condition.

Breast-feeding

It is not known whether Glup 500 MG Tablet passes into breast milk. Hence is not recommended for use during breastfeeding. Your physician may advise a safer alternative with the same therapeutic effect based on your clinical condition.
General warnings

Kidney diseases

Glup 500 MG Tablet may cause damage to the kidneys when used in the presence of kidney problems. Close monitoring of kidney function may be required.

Stress

Use of Glup 500 MG Tablet should be discontinued in people exposed to stressful conditions such as a fever, trauma (severe injury), surgeries, or accidents since it may not be effective in controlling blood sugar levels in these conditions.

Type I diabetes

Glup 500 MG Tablet is not recommended for use in people having Type I diabetes (a condition where the pancreas produces little or no insulin) since it is not effective in treating such cases.

Diarrhoea

Glup 500 MG Tablet may cause diarrhoea during the initial stage of therapy which mostly subsides by itself. However, if the problem persists for a longer duration contact your doctor immediately.

Missed Dose

Try not to skip a dose of Glup 500 MG Tablet. In case a dose is skipped, do not add it up to the next dose.

Overdose

Reach the nearest emergency medical department immediately or contact your doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol should be avoided while treatment with Glup 500 MG Tablet due to severe side effects like reduced blood sugar levels, dizziness etc.
Interaction with Medicine

Amlodipine

Estradiol

Gatifloxacin

Iodinated Contrast Media

Formoterol

Disease interactions

Vitamin B12 deficiency

Glup 500 MG Tablet should be used with extreme caution if you have vitamin B12 deficiency since it may worsen your condition. Appropriate vitamin B12 supplementation and dose adjustments may be required based on your clinical condition.

Cardiovascular disease

Glup 500 MG Tablet should be taken with caution if you have heart problems or problems associated with blood vessels due to the increased risk of severe side effects. Close monitoring of heart function and vital signs is recommended.

Lactic Acidosis

Glup 500 MG Tablet may cause lactic acidosis if you have septicemia (blood poisoning), kidney and heart problems. Therefore, close monitoring of blood glucose levels, kidney function, heart function, and liver function may be required.

Hypoglycemia

Glup 500 MG Tablet should be taken with caution if you have hypoglycemia (low blood sugar levels). Close monitoring of blood sugar levels is recommended.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Glup 500 MG Tablet as instructed by your doctor. Your dose is likely to change over time based on therapeutic response and clinical condition. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. You should always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels. Always maintain a strict exercise and diet regimen for better results.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Glup 500 MG Tablet decreases the absorption of glucose (sugars) from the intestine and glucose production in the liver which in turn increases the action of insulin in your body. Thereby reducing blood sugar levels.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Non-sulfonylureas, Oral Biguanides

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - METFORMIN HCL tablet. [online] Available at: [Accessed 8 June 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d98aea3-35ba-447a-b88f-a5a20b612b2f

Medicines.org.uk. 2021. [online] Available at: [Accessed 8 June 2021].

https://www.medicines.org.uk/emc/PIL.26348.latest.pdf

Drugs, H., 2021. Metformin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 8 June 2021].

https://medlineplus.gov/druginfo/meds/a696005.html

Johnson, N., 2021. Metformin use in women with polycystic ovary syndrome. [online] PubMed Central (PMC). Available at: [Accessed 8 June 2021].

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4200666/

Ajog.org. 2021. [online] Available at: [Accessed 8 June 2021].

https://www.ajog.org/article/S0002-9378(08)01047-8/pdf

Pubchem.ncbi.nlm.nih.gov. 2021. Metformin. [online] Available at: [Accessed 8 June 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/4091#section=Top
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Information on this page was last updated on 23 Feb 2023

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