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Instarise 50 mg Tablet
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Instarise 50 mg Tablet

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsSildenafil
Description
Instarise 50 mg Tablet contains Sildenafil. It is better known as the blue pill. It is an effective medicine used for the treatment of erectile dysfunction (ED) in men. Erectile dysfunction is a condition where a man is unable to achieve and/or maintain an erection adequate for sexual intercourse. This happens because of decreased blood flow due to physical injuries and certain medical conditions, or due to some psychological conditions such as anxiety, stress, depression, etc. Instarise 50 mg Tablet relaxes the blood vessels and helps in increasing the flow of blood to the penis. Some side effects of Instarise 50 mg Tablet include flushing (redness and feeling of warmth), headache, stomach upset, dizziness, blurred vision, etc. Usually, these side effects get resolved on their own. Consult your doctor if these side effects worsen or persist for a long time. Instarise 50 mg Tablet can be taken with or without food, as prescribed by your doctor. It is recommended that you take the tablet 30-60 minutes before having sex. However, you can also take it up to 4 hours prior to sex. This medicine will help you get/maintain the erection only if you are sexually stimulated. Do not take extra pills for quick results. Instarise 50 mg Tablet is intended only for men. It is not recommended for use in women and children. Instarise 50 mg Tablet is not recommended for people with heart and kidney problems, Avoid taking this tablet if you have a recent history of stroke or angina (chest pain and discomfort). Avoid or limit drinking alcohol during the treatment as it makes you feel dizzy. Do not drive or operate machines while you are under treatment with Instarise 50 mg Tablet.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Instarise 50 mg Tablet

Rezum 50 MG Tablet
Dr. Reddys Laboratories Ltd.
Viagra 50 MG Tablet
Pfizer Ltd.
Vigore 50 MG Tablet
Zydus Cadila
Viraha 50 MG Tablet
Micro Labs Ltd.
Kamagra Gold 50 mg Tablet
Ajanta Pharma Ltd.

Side effects

Major & minor side effects for Instarise 50 mg Tablet

  • Headache
  • Nosebleed
  • Indigestion
  • Trouble sleeping
  • Diarrhoea
  • Dizziness
  • Bloody and cloudy urine
  • Burning, numbness, tingling in the arms and feet
  • Visual disturbances
  • Sensitivity to light
  • Prolonged and painful erection
  • Painful urination
  • Excessive tearing of the eye
  • Ringing or buzzing in the ears
  • Deafness
  • Nasal congestion
  • Nausea
  • Redness of the skin especially on the face and neck

Uses of Instarise 50 mg Tablet

What is it prescribed for?

  • Erectile Dysfunction
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Instarise 50 mg Tablet can be observed within 30 to 60 minutes of taking the tablet.
  • How long do the effects of this medicine last?
    Instarise 50 mg Tablet may remain in the body for 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol while taking Instarise 50 mg Tablet as it lowers blood pressure. Side effects such as dizziness, fainting, flushing, persistent headaches, changes in heart rate, etc. may occur.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported for Instarise 50 mg Tablet.
  • Can this medicine be taken during pregnancy?
    Instarise 50 mg Tablet is not recommended for use in women.
  • Can this medicine be taken while breast-feeding?
    Instarise 50 mg Tablet is not recommended for use in women.

Allergy

Avoid taking Instarise 50 mg Tablet if you have a history of allergy to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Nitrate containing medicines

If you have been prescribed any medicine that contains nitrates such as Nitroglycerin, Isosorbide, etc, avoid taking Instarise 50 mg Tablet as it lowers blood pressure and leads to cardiovascular collapse (a dangerous drop in the blood pressure that can be fatal). The risk of other side effects such as dizziness, lightheadedness, fainting, headache, flushing, heart palpitations, and priapism (prolonged and painful erection unrelated to sexual activity) may also increase.

Riociguat

Riociguat is a medicine that is used to treat pulmonary arterial hypertension (PAH; high blood pressure in the vessels that carry blood to the lungs). Instarise 50 mg Tablet is not recommended for use if you are on treatment with Riociguat as it may significantly lower your blood pressure, which can be dangerous. You may also experience other side effects such as dizziness, lightheadedness, fainting, flushing, headache, and nasal congestion.

Cardiac insufficiency

Cardiac insufficiency (heart failure), is when the heart muscle is not able to pump blood as well as it should. People having severe unstable angina (chest pain) or severe cardiac failure should not take Instarise 50 mg Tablet. Sexual activity is also not recommended in such cases due to the potential risk of a heart attack. This medicine affects the blood vessels of the heart also and could lead to other heart problems.
Warnings for special population

Pregnancy

Instarise 50 mg Tablet is not recommended for use in women.

Breast-feeding

Instarise 50 mg Tablet is not recommended for use in women.
General warnings

Hypotension

Instarise 50 mg Tablet can cause mild and short-lasting hypotension (decreased blood pressure levels) as it relaxes the blood vessels. Be careful if you are taking it along with any medication for lowering high blood pressure levels.

Priapism

Priapism, a painful erection lasting for more than 4 hours. Instarise 50 mg Tablet may cause priapism in some people. Priapism may result in penile tissue damage and permanent loss of potency if not treated promptly. Use Instarise 50 mg Tablet with caution in such conditions. If an erection persists longer than 4 hours, you should seek immediate medical assistance.

Loss of hearing

Instarise 50 mg Tablet has been associated with a sudden decrease or loss of hearing. It may be accompanied by tinnitus (ringing of ears) or dizziness as the increased blood flow to the ears may cause damage. This tablet is not recommended for people having hearing problems. Seek prompt medical attention if you experience any hearing loss after taking this medicine.

Surgery

Instarise 50 mg Tablet can cause a severe drop in your blood pressure when combined with the effects of anaesthesia and other drugs used during surgery. If you are taking this medicine, inform your doctor before undergoing any surgery.

Use in children

Instarise 50 mg Tablet is not recommended for use in children less than 18 years of age as the safety and efficacy data of this medicine are not clinically established.

Counseling

The underlying cause of erectile dysfunction may be physical, psychological, or both. It is important to determine the underlying cause of erectile dysfunction to devise an appropriate plan of treatment. Counselling and therapy can increase the effectiveness of Instarise 50 mg Tablet.

Use in females

Instarise 50 mg Tablet is not recommended for use in females.

Effect on vision

Cases of visual defect have been reported with Instarise 50 mg Tablet especially if used together with other PDE5 inhibitors (Phosphodiesterase type 5) medicines. If you experience any sudden loss of vision, stop taking the medicine and contact your doctor immediately.

Effect on bleeding

Instarise 50 mg Tablet has to be used with caution if you have gastrointestinal bleeding or active ulcer as no safety information is available.

Ability to drive or operate machines

Instarise 50 mg Tablet may not severely affect your ability to drive or operate machines. It is important that you become aware of how the medicine affects your body.

Missed Dose

Instarise 50 mg Tablet is used as a single dose when required, so the chances of missing a dose are less.

Overdose

Never take more than the prescribed dose. If you have intentionally or accidentally consumed more than the prescribed amount of Instarise 50 mg Tablet, then you might feel severe dizziness, fainting, painful/prolonged erection. Contact your doctor immediately for further guidance.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol while taking Instarise 50 mg Tablet as it lowers blood pressure. Side effects such as dizziness, fainting, flushing, persistent headaches, changes in heart rate, etc. may occur.
Interaction with Medicine

Amlodipine

Carbamazepine

Clarithromycin

Dexamethasone

Ketoconazole

Nitroglycerin

Isoniazid

Warfarin

Disease interactions

Cardiovascular diseases

Instarise 50 mg Tablet is not recommended in people with heart problems. This medicine affects the blood vessels of the heart also and could increase the risk of heart problems.

Kidney Disease

Instarise 50 mg Tablet is excreted through the kidneys. If you have pre-existing kidney problems, using this tablet will cause further damage to your kidneys. Instarise 50 mg Tablet is not recommended in people with severe kidney problems or on renal dialysis.

Disease of the retina

Instarise 50 mg Tablet is not recommended for use if you have medical conditions related to the retina (part of your eye that is responsible for vision) where colour discrimination is impaired. This tablet may worsen the condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Instarise 50 mg Tablet with or without food but if you have taken a heavy meal, it may take longer to work. Do not crush, break or chew the tablet. Avoid taking it more than once a day. It is not recommended to give your medicine to other people even if their condition appears to be the same as yours. It is advisable to take Instarise 50 mg Tablet an hour before sexual intercourse. But, you can take it anytime between 30 minutes and 4 hours before sexual activity. Seek medical attention if the erection persists for more than 4 hours after sexual intercourse. It is important to note that this medicine will not work without sexual stimulation. This medicine does not cure erectile dysfunction. Factors such as obesity, smoking, drinking, etc., could also contribute to erectile dysfunction. Follow major lifestyle modifications like quitting smoking and drinking, weight management, eating a healthy diet, and exercising along with Instarise 50 mg Tablet. Remember that Instarise 50 mg Tablet does not offer any protection against sexually transmitted diseases (STDs) such as syphilis, gonorrhoea, HIV, etc. hence, adequate safety measures should be taken while having sexual intercourse.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Instarise 50 mg Tablet has Sildenafil which works by relaxing the smooth muscles in the penis and increases blood flow. This helps the penis to harden and leads to an erection.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Drugs for erectile dysfunction and ejaculatory disorder, Phosphodiesterase-5 inhibitors

Schedule

Schedule H

Medicines.org.uk. 2021. Sildenafil 100 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 7 July 2021].

https://www.medicines.org.uk/emc/product/7124/smpc>

Dailymed.nlm.nih.gov. 2021. DailyMed - SILDENAFIL CITRATE- sildenafil tablet, film coated. [online] Available at: < [Accessed 7 July 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b48630b1-5208-4d00-b56f-21701f223758>

Pubchem.ncbi.nlm.nih.gov. 2021. CID 5212. [online] Available at: < [Accessed 7 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/5212>

Drugs, H., 2021. Sildenafil: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 7 July 2021].

https://medlineplus.gov/druginfo/meds/a699015.html>

Drugbank.ca. 2021. Sildenafil: Uses, Interactions, Mechanism of Action | DrugBank Online. [online] Available at: < [Accessed 7 July 2021].

https://www.drugbank.ca/drugs/DB00203>

Viagra.com. 2021. ED Treatment | VIAGRA® (sildenafil citrate) | Safety Info. [online] Available at: < [Accessed 7 July 2021].

https://www.viagra.com/>
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Information on this page was last updated on 12 Oct 2022

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