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Lupisulin-M 30 (30/70) 100 IU Injection

Manufactured byLUPIN LTD
ContainsRegular Human Insulin (30 International units ) + Insulin - Neutral Protaminated Hagedorn (NPH) (70 International units )
Description
Lupisulin-M 30 (30/70) 100 IU Injection is a combination of short-acting and intermediate-acting analogues of insulin. It is used for the treatment of diabetes mellitus type-I (high blood sugar levels due to genetic conditions) and type-II (high blood sugar levels due to inadequate insulin). This medicine helps in the utilization of glucose and controlling blood sugar levels in such cases. Lupisulin-M 30 (30/70) 100 IU Injection may cause side effects like nausea, vomiting, pain at the injection site, diarrhoea etc. Consult your doctor if these side effects get worse or persistent. Avoid driving vehicles or operating machines after taking this medicine as it can make you feel drowsy and/or dizzy. Lupisulin-M 30 (30/70) 100 IU Injection is available as injection/pen. Take this medicine at the same time every day to maintain a constant level of medicine in your body. Inject this medicine before 30 minutes of having your meal. Do not stop taking this medicine without consulting your doctor, as your symptoms may reoccur. Lupisulin-M 30 (30/70) 100 IU Injection is not recommended if you are allergic to it. Inform your doctor all about your current medications and existing medical conditions. This will help your doctor to adjust your dose for avoiding side effects. If you are pregnant or breastfeeding, consult your doctor before using this medicine.

Side effects

Major & minor side effects for Lupisulin-M 30 (30/70) 100 IU Injection

  • Tingling of hands or feet
  • Dry mouth
  • Diarrhoea
  • Headache
  • Sneezing
  • Fever
  • Body pain
  • Unusual weight gain or loss
  • Nausea and vomiting
  • Pain at the injection site
  • Dizziness
  • Drowsiness
  • Confusion
  • Changes in vision
  • Chills
  • Slurred speech
  • Shortness of breath
  • Anxiety
  • Swelling in the arms or legs.
  • Convulsions (fits)
  • Loss of consciousness

Uses of Lupisulin-M 30 (30/70) 100 IU Injection

What is it prescribed for?

  • Type I Diabetes mellitus
  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Lupisulin-M 30 (30/70) 100 IU Injection can be observed within 30 minutes of taking the dose.
  • How long do the effects of this medicine last?
    The duration of action of Lupisulin-M 30 (30/70) 100 IU Injection is 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Lupisulin-M 30 (30/70) 100 IU Injection due to the increased risk of hypoglycemia (low blood glucose levels) and hyperglycemia (high blood glucose levels) depending on the quantity and frequency of alcohol consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Lupisulin-M 30 (30/70) 100 IU Injection.
  • Can this medicine be taken during pregnancy?
    Lupisulin-M 30 (30/70) 100 IU Injection is considered safe for use if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Lupisulin-M 30 (30/70) 100 IU Injection is considered to be safe if you are breastfeeding. Although you might require adjustments in doses of insulin. Consult your doctor before taking this medicine.

Allergy

Lupisulin-M 30 (30/70) 100 IU Injection is not recommended if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Hypoglycemia

Lupisulin-M 30 (30/70) 100 IU Injection is not recommended if you have hypoglycemia (low blood sugar levels) as it may further lower your blood sugar level.
Warnings for special population

Pregnancy

Lupisulin-M 30 (30/70) 100 IU Injection is considered safe for use if you are pregnant.

Breast-feeding

Lupisulin-M 30 (30/70) 100 IU Injection is considered to be safe if you are breastfeeding. Although you might require adjustments in doses of insulin. Consult your doctor before taking this medicine.
General warnings

Diabetic ketoacidosis

Diabetic ketoacidosis (DKA) is a life-threatening problem where the body produces excess blood acids (ketones). Lupisulin-M 30 (30/70) 100 IU Injection is not recommended for the treatment of diabetic ketoacidosis due to the delayed onset of action.

Driving and operating machinery

Lupisulin-M 30 (30/70) 100 IU Injection may cause blurred vision or dizziness. Therefore, avoid performing activities like driving vehicles or operating machines while using this medicine.

Changing the type and brand of insulin

Using a different brand or type of insulin should be done only under strict medical supervision.

Single person use

Lupisulin-M 30 (30/70) 100 IU Injection should not be shared with others even if the needle is changed. Sharing syringes or needles with another person, who is using vials is strictly not advised.

Missed Dose

Lupisulin-M 30 (30/70) 100 IU Injection is administered before food. In case of a missed dose, administer the medicine after the meal. If the time gap is more since the meal, consult your doctor whether to inject the missed dose or not. Do not administer extra medicine to make up for a missed dose.

Overdose

Seek immediate medical attention if an overdose of Lupisulin-M 30 (30/70) 100 IU Injection is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Lupisulin-M 30 (30/70) 100 IU Injection due to the increased risk of hypoglycemia (low blood glucose levels) and hyperglycemia (high blood glucose levels) depending on the quantity and frequency of alcohol consumption.
Interaction with Medicine

Corticosteroids

Beta blockers

ACE inhibitors

Gatifloxacin

Fluoroquinolones

Aspirin

Disease interactions

Kidney disease

Lupisulin-M 30 (30/70) 100 IU Injection should be used with caution if you have kidney problems as an affected kidney will not be able to filter the medicine properly. This can increase the risk of toxicity. Your doctor will monitor your kidney functions closely and/or adjust your dose if required.

Hypokalemia

Lupisulin-M 30 (30/70) 100 IU Injection should be used with caution if you have hypokalemia (low blood potassium levels) as it may worsen your condition. Your doctor may regularly monitor your potassium levels.

Liver Disease

Lupisulin-M 30 (30/70) 100 IU Injection should be used with extreme caution if you have liver problems as this medicine is broken down and absorbed in the liver. If there are any liver conditions, the metabolites may accumulate resulting in toxicity.
Food interactions
Information not available.
Lab interactions
Information not available.
Use Lupisulin-M 30 (30/70) 100 IU Injection as instructed by your doctor. The needle should be kept under the skin for at least six seconds to make sure the entire dose is injected. The site where the injection is given should be changed every month in order to avoid lipodystrophy (a condition where the fat under the skin breaks down and forms lumps that interfere with insulin absorption). Never share an injection pen, cartridge, or syringe with another person, even if the needle has been changed. Eat a high carbohydrate meal within 30 minutes after using the injection. Keep this medicine away from children and pets. Do not take it in larger or smaller amounts than advised/prescribed. Consult your doctor if you experience any undesirable side effects.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Lupisulin-M 30 (30/70) 100 IU Injection is a replacement for insulin which works by enhancing the glucose uptake for energy production. This helps in controlling blood sugar levels.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Insulin, Insulin analog combination, Antidiabetic agents

Schedule

Schedule H

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https://www.ema.europa.eu/en/documents/product-information/mixtard-epar-product-information_en.pdf>

Mcs.open.ac.uk. 2021. Human. [online] Available at: < [Accessed 24 November 2021].

http://mcs.open.ac.uk/nlg/old_projects/pills/corpus/base/data/Novo_Nordisk/Human_Mixtard_30_Pen/Human_Mixtard_30_Pen.html>

Cigna.com. 2021. insulin isophane and insulin regular | Cigna. [online] Available at: < [Accessed 24 November 2021].

https://www.cigna.com/individuals-families/health-wellness/hw/medications/insulin-isophane-and-insulin-regular-d04374a1>

Ebs.tga.gov.au. 2021. TGA eBS - Product and Consumer Medicine Information Licence. [online] Available at: < [Accessed 24 November 2021].

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2011-PI-02733-3&d=201905171016933>
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Information on this page was last updated on 7 Dec 2021

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