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Mahagaba M 75 Capsule
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Mahagaba M 75 Capsule

Manufactured byMANKIND PHARMACEUTIALS LTD.
ContainsPregabalin (75 mg) + Methylcobalamin (750 mcg)
Description
Mahagaba M 75 Capsule medicine consisting of Mecobalamin and Pregabalin. It is used for the treatment of peripheral neuropathy (weakness, numbness and pain from nerve damage, usually in the hands and feet) in adults. Mahagaba M 75 Capsule relieves pain by inactivating certain chemical messengers in the brain and repairing damaged nerve cells and fibres. Mahagaba M 75 Capsule can cause side effects such as dizziness, drowsiness, tiredness and uncoordinated body movements. These side effects are temporary and can usually resolve with time. Consult your doctor if these effects persist for a long time. Keep a check of your mood and behaviour as this medicine can cause mood and behaviour changes like depression and suicidal tendencies. In such cases, contact your doctor immediately. Mahagaba M 75 Capsule is recommended to be taken with or without food. To maintain constant levels of this medicine, take it at the same time every day. Use this medicine in the dose and duration as prescribed by your doctor. It is recommended that you should not stop taking this medicine without consulting your doctor. If stopped abruptly, you might experience withdrawal symptoms like anxiety, fatigue, sweating, vomiting, depression, seizures, and hallucinations. Mahagaba M 75 Capsule is not recommended for use in children less than 18 years of age. Inform your doctor if you have medical complications associated with kidney or liver conditions as Mahagaba M 75 Capsule may worsen these conditions. Mahagaba M 75 Capsule is not recommended if you are pregnant, or are breastfeeding. Your doctor may prescribe this medicine only when the benefits outweigh the risks, or another suitable medicine may be prescribed. Mahagaba M 75 Capsule may cause drowsiness. Do not consume alcohol while using Mahagaba M 75 Capsule, as it can lead to excessive drowsiness. Be careful when you rise from a sitting or lying position, as this medicine may cause dizziness.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Mahagaba M 75 Capsule

  • Difficulty in breathing
  • Chest tightness
  • Chills
  • Severe diarrhoea
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Blurred or double vision
  • Dizziness
  • Headache
  • Fever
  • Anxiety and nervousness
  • Slurred speech
  • Trouble sleeping
  • Loss of bladder control
  • Burning, numbness, tingling in the arms and feet
  • Nausea and vomiting
  • Loss of appetite
  • Uncoordinated body movements
  • Drowsiness

Uses of Mahagaba M 75 Capsule

What is it prescribed for?

  • Peripheral neuropathy
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time taken by Mahagaba M 75 Capsule to show its effect is 1 hour after taking it. However, it may vary from person to person.
  • How long do the effects of this medicine last?
    The amount of time for which Mahagaba M 75 Capsule remains effective is 2 days. However, it may vary from person to person.
  • Is it safe to consume alcohol while taking this medicine?
    Alcohol should not be consumed while using Mahagaba M 75 Capsule since it may increase the risk of drowsiness, dizziness, and difficulty concentrating.
  • Is this a habit forming medicine?
    Mahagaba M 75 Capsule has a low abuse potential with limited physical and psychological dependence.
  • Can this medicine be taken during pregnancy?
    Mahagaba M 75 Capsule is not recommended for use in pregnancy as it may harm your foetus. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Mahagaba M 75 Capsule is not recommended for use in breastfeeding as it may pass into breastmilk and harm your baby. Consult your doctor before taking this medicine.

Allergy

Avoid receiving Mahagaba M 75 Capsule if you have a known allergy to this medicine. Seek medical attention if you experience any undesirable effects such as skin rash, hives (itchy, raised scars that are found on the skin), swelling (of face, lips, tongue), etc.

Leber's Disease

Leber's Disease is a condition inherited from your mother. It causes you to lose your eyesight, starting with painless blurriness. Mahagaba M 75 Capsule is not recommended for use in patients suffering from Leber's Disease, a rare genetic disorder.
Warnings for special population

Pregnancy

Mahagaba M 75 Capsule is not recommended for use in pregnancy as it may harm your foetus. Consult your doctor before taking this medicine.

Breast-feeding

Mahagaba M 75 Capsule is not recommended for use in breastfeeding as it may pass into breastmilk and harm your baby. Consult your doctor before taking this medicine.
General warnings

Kidney disease and dialysis

Mahagaba M 75 Capsule should be used with extreme caution if you have an impaired kidney function. Your doctor will advise kidney tests while taking this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on your condition and therapeutic response.

Suicidal tendencies

Mahagaba M 75 Capsule may cause suicidal ideation (suicidal thoughts). Caution should be maintained while using this medicine if you have any psychological condition. Your doctor may monitor you closely for any mood and behavioural changes. Replacement with a suitable alternative should be considered based on your clinical condition.

Driving or operating machines

Mahagaba M 75 Capsule may increase your risk of experiencing drowsiness, dizziness, difficulty in concentrating, etc. Hence, activities that need a high level of mental attention like driving vehicles or operating heavy machines should be avoided.

Withdrawal symptoms

Do not stop using Mahagaba M 75 Capsule abruptly. The risk of withdrawal symptoms is significantly high if it is discontinued suddenly. Complete the treatment with this medicine as prescribed by your doctor.

Oedema

Mahagaba M 75 Capsule may increase the risk of oedema. Hence, it should be used with caution if you have any condition of fluid retention. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition.

Heart block

Mahagaba M 75 Capsule may cause heart rhythm abnormalities which could result in a blockage and associated complications. It should be used with caution if you have any condition related to the heart and blood vessels. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition.

Potential for abuse

Mahagaba M 75 Capsule may cause dependence, especially in chronic alcohol users or in people who have used other habit-forming agents in the past. Report the past use of alcohol or other drugs to your doctor before receiving this medicine. Your doctor may consider replacing it with a suitable alternative based on your clinical condition.

Rhabdomyolysis

Mahagaba M 75 Capsule has been associated with rare cases of muscle breakdown conditions that affect kidneys. You should report any instance of muscle pain, weakness, the presence of dark reddish colouration of urine, etc., to your doctor on priority. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition.

Use in elderly

Mahagaba M 75 Capsule should be used with caution in elderly. Appropriate dose adjustments or replacement with a suitable alternative may be required in elderly people.

Gastrointestinal surgery

Mahagaba M 75 Capsule should be used with caution in people who have had recent surgery of the stomach or intestines, as they may have reduced absorption of this medicine.

Use in children

Mahagaba M 75 Capsule is not recommended for use in children less than 18 years of age since the safety and effectiveness of this medicine are not studied.

Missed Dose

Take the missed dose of Mahagaba M 75 Capsule as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to compensate for the missed one.

Overdose

Seek emergency medical treatment or contact your doctor if you suspect that you might have taken an overdose of Mahagaba M 75 Capsule.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Alcohol should not be consumed while using Mahagaba M 75 Capsule since it may increase the risk of drowsiness, dizziness, and difficulty concentrating.
Interaction with Medicine

Chloramphenicol

Lorazepam

Omeprazole

Ranitidine

Buprenorphine

Oxycodone

Propoxyphene

Hypoglycemic agents

ACE inhibitors

Disease interactions

Angioedema

Mahagaba M 75 Capsule should be used with caution if you have a known history of angioedema (painless swelling under the skin, triggered by an allergy to animal dander, pollen, drugs, venom, food or medication) since it may worsen your condition. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative as needed, based on your clinical condition and therapeutic response.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Mahagaba M 75 Capsule with or without food as instructed by your doctor. Do not take in larger or smaller amounts than prescribed. Ensure that the course of treatment is completed and do not stop without consulting your doctor since this may cause severe withdrawal symptoms. Consult the doctor if you developed any unusual mood changes, depression, and suicidal thoughts while taking this medicine. Keep the medicine away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Pregabalin reduces pain by inactivating certain chemical transmitters in the brain and blocking the nerve impulses. Methylcobalamin repairs and rejuvenates damaged nerve cells. Together they relieve pain and repair nerve damage.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Gamma-aminobutyric acid analogs, Vitamins

Schedule

Schedule H

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https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021446s026,022488s005lbl.pdf>

CiplaMed. 2021. NOVA M Capsules. [online] Available at: < [Accessed 12 August 2021].

https://ciplamed.com/content/nova-m-capsules>

Dailymed.nlm.nih.gov. 2021. DailyMed - PREGABALIN capsule. [online] Available at: < [Accessed 12 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=54e6d137-a495-4b87-b3c2-2f5a0226dd3e>

Drugs, H., 2021. Pregabalin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 12 August 2021].

https://medlineplus.gov/druginfo/meds/a605045.html>

Ods.od.nih.gov. 2021. Office of Dietary Supplements - Vitamin B12. [online] Available at: < [Accessed 12 August 2021].

https://ods.od.nih.gov/factsheets/VitaminB12-HealthProfessional/>

Pubchem.ncbi.nlm.nih.gov. 2021. Methylcobalamin. [online] Available at: < [Accessed 12 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Methylcobalamin>
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Information on this page was last updated on 28 Oct 2021

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