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Mahalevo 0.5 % Infusion
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Mahalevo 0.5 % Infusion

Manufactured byMankind Pharmaceuticals Ltd.
ContainsLevofloxacin
Description
Mahalevo 0.5 % Infusion is fluoroquinolone antibiotic used for the treatment of bacterial infections affecting the lungs, skin and urinary tract - the kidneys, bladder, ureters, or urethra. This injection is effective against a large number of bacteria. It kills or prevents the growth of bacteria in the body. It is not effective against infections caused by viruses. The side effects of Mahalevo 0.5 % Infusion are diarrhoea, skin rash, pain at the injection site, headache, weakness, and dizziness. It can also cause muscle damage, usually in the ankle. These side effects are temporary and they self-resolve within a few days after the treatment. Mahalevo 0.5 % Infusion is injected into a vein. Your doctor will determine how many doses you need each day and how often the injections should be given. Once an antibiotic is started, it is always recommended to finish the entire course of treatment.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Mahalevo 0.5 % Infusion

  • Diarrhoea
  • Stomach pain
  • Headache
  • Sleeplessness
  • Skin rash
  • Constipation
  • Dizziness
  • Nausea or vomiting
  • Pain at the injection site

Uses of Mahalevo 0.5 % Infusion

What is it prescribed for?

  • Cystitis
  • Pyelonephriits
  • Skin and soft tissue infections
  • Community-Acquired Pneumonia
  • Bronchitis
  • Inhalation Anthrax
  • Plague
  • Complicated urinary tract infections
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of levofloxacin injection starts immediately after the administration. You will start to feel better in 3 to 5 days after receiving levofloxacin injection.
  • How long do the effects of this medicine last?
    The effect of levofloxacin injection lasts for about 12 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Mahalevo 0.5 % Infusion.
  • Can this medicine be taken during pregnancy?
    Mahalevo 0.5 % Infusion should be avoided during pregnancy due to the risk of adverse effects on the baby's developing joints. It is not known to cause harmful effects on the baby if is used later in pregnancy. Use Mahalevo 0.5 % Infusion only upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    Mahalevo 0.5 % Infusion is not known to be harmful in breastfeeding women. It passes into breast milk in small amounts. Hence it is acceptable for use in nursing mothers upon your doctor's recommendation. Baby should be observed for symptoms such as diarrhoea and yeast infection.

Allergy

Avoid using Mahalevo 0.5 % Infusion if you are previously allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Tendinitis or tendon rupture

Mahalevo 0.5 % Infusion can cause muscle damage especially in old age. Do not use Mahalevo 0.5 % Infusion if you have tendonitis (swelling of fibres that attach bone with muscles) or tendon rupture (a partial or complete tear of the tendon- the tissue that connects muscle to bone).

Myasthenia gravis

Myasthenia gravis is a skeletal muscle weakness condition characterized by severe weakness of any of the muscles under your voluntary control, including the arms and legs. Mahalevo 0.5 % Infusion should be avoided in patients with myasthenia gravis since it may get worsen.
Warnings for special population

Pregnancy

Mahalevo 0.5 % Infusion should be avoided during pregnancy due to the risk of adverse effects on the baby's developing joints. It is not known to cause harmful effects on the baby if is used later in pregnancy. Use Mahalevo 0.5 % Infusion only upon your doctor's recommendation.

Breast-feeding

Mahalevo 0.5 % Infusion is not known to be harmful in breastfeeding women. It passes into breast milk in small amounts. Hence it is acceptable for use in nursing mothers upon your doctor's recommendation. Baby should be observed for symptoms such as diarrhoea and yeast infection.
General warnings

Muscle damage

Mahalevo 0.5 % Infusion can cause muscle damage usually on the tendons that surround the ankle. Inform your doctor if you feel pain, numbness, or tingling sensations in your muscles.

Antibiotic resistance

The entire course of treatment with Mahalevo 0.5 % Infusion should be completed, even if the condition gets better to avoid antibiotic resistance.

Diarrhoea

Mahalevo 0.5 % Infusion can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor if you experience severe diarrhoea while receiving this medicine.

Missed Dose

Since Mahalevo 0.5 % Infusion is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since Mahalevo 0.5 % Infusion is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Corticosteroids

Quinidine

Aspirin

Disease interactions

Central nervous system disorders

Use Mahalevo 0.5 % Infusion with caution in patients with nerve problems, seizures, depression, and psychotic reactions. Mahalevo 0.5 % Infusion can trigger these conditions and inform your doctor immediately if these reactions occur.

Colitis

Use Mahalevo 0.5 % Infusion with extreme caution in patients with gastrointestinal (mouth to anus) diseases, particularly colitis (swelling of the inner lining of the colon), since it may worsen the patient's condition.

QT Prolongation

Mahalevo 0.5 % Infusion may cause heart rhythm problem called prolonged QT intervals (an electrical heartbeat disturbance) in some patients who are taking heart medications. It may result in fast, rapid, and irregular heartbeats.

Kidney disease

Patients with kidney diseases need special consideration while using Mahalevo 0.5 % Infusion due to the risk of kidney damage. Dose adjustment should be done based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Mahalevo 0.5 % Infusion should be administered by a qualified healthcare professional in the clinical or hospital setting. Report any undesirable side effects to the doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Mahalevo 0.5 % Infusion stops the action of a bacterial enzyme called DNA-gyrase. This helps to kill or prevent the growth of bacteria in the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Quinolones, Antibiotics

Schedule

Schedule H

Go.drugbank.com. 2021. Levofloxacin | DrugBank Online. [online] Available at: < [Accessed 3 February 2021].

https://go.drugbank.com/drugs/DB01137>

Pubchem.ncbi.nlm.nih.gov. 2021. Levofloxacin. [online] Available at: < [Accessed 3 February 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Levofloxacin>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 4 February 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020634s040,020635s043,021721s007lbl.pdf>

Drugs, H., 2021. Levofloxacin Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 4 February 2021].

https://medlineplus.gov/druginfo/meds/a601154.html>

Medicines.org.uk. 2021. Levofloxacin 500mg/100ml solution for infusion vials (5mg/ml in 100ml vials) - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 4 February 2021].

https://www.medicines.org.uk/emc/product/8839/smpc#gref>
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Information on this page was last updated on 4 Feb 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.