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Metox Am (5/25 mg) Tablet
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Metox Am (5/25 mg) Tablet

Manufactured byWockhardt Ltd.
ContainsAmlodipine (5 mg) + Metoprolol (25 mg)
Description
Metox Am (5/25 mg) Tablet is a combination of Amlodipine and Metoprolol. It is used to treat high blood pressure. This medicine works by relaxing your blood vessels and lowering your blood pressure. Metox Am (5/25 mg) Tablet may cause common side effects such as headache, dizziness, nausea, muscle cramps, diarrhoea/constipation, etc. Consult your doctor if these symptoms persist or if they become severe. Metox Am (5/25 mg) Tablet should be taken exactly as advised by your doctor. Take it at the same time every day to maintain a constant level of this medicine in your body. Metox Am (5/25 mg) Tablet should be avoided if you are allergic to it. Inform your doctor if you have diabetes (high blood sugar levels), liver, kidney problems, or a history of glaucoma (a condition where the pressure in the eyeballs is abnormally high that can lead to eventual loss of vision), before taking this medicine. Metox Am (5/25 mg) Tablet may interact with other medicines. Close evaluation with respect to your current medicines is necessary to avoid any undesired side effects. If you are pregnant, breastfeeding, or are planning a pregnancy, consult your doctor before taking this medication.
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Side effects

Major & minor side effects for Metox Am (5/25 mg) Tablet

  • Oedema (accumulation of water in the tissues)
  • Headache
  • Dizziness
  • Abdominal pain
  • Nausea
  • Constipation
  • Indigestion
  • Tiredness and weakness
  • Visual disturbances
  • Muscle cramps
  • Swelling of ankles
  • Orthostatic hypotension (A sudden drop in blood pressure when standing up from sitting or lying down position)

Uses of Metox Am (5/25 mg) Tablet

What is it prescribed for?

  • Hypertension
  • Ischemic heart disease
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Metox Am (5/25 mg) Tablet shows its effect within one hour of intake.
  • How long do the effects of this medicine last?
    The effect of Metox Am (5/25 mg) Tablet lasts for a duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended when on treatment with Metox Am (5/25 mg) Tablet as it may lower your blood pressure. You may also experience headaches, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported with Metox Am (5/25 mg) Tablet.
  • Can this medicine be taken during pregnancy?
    Metox Am (5/25 mg) Tablet may cause severe side effects in your foetus and hence is not recommended during pregnancy unless necessary. If you are pregnant consult your doctor.
  • Can this medicine be taken while breast-feeding?
    Metox Am (5/25 mg) Tablet passes into breastmilk and may cause side effects in your infant. If you are breastfeeding, consult your doctor.

Allergy

Avoid taking Metox Am (5/25 mg) Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of your face/tongue/throat), severe dizziness, breathing difficulty, etc.

Severe heart disease

Metox Am (5/25 mg) Tablet is not recommended if you have a history of severe heart problems such as aortic stenosis (narrowing of your heart valve), uncontrolled heart failure, and cardiogenic shock (conditions where your heart is unable to supply enough blood to your body), blocked blood vessels, prinzmetal’s angina (chest pain during periods of rest) as it may worsen your condition.

Peripheral Arterial Disease

Metox Am (5/25 mg) Tablet is not recommended for you if you have blood circulation disorders like peripheral arterial disease (a condition where the blood vessels are narrow, leading to decreased blood flow to your limbs) as it may worsen your condition.
Warnings for special population

Pregnancy

Metox Am (5/25 mg) Tablet may cause severe side effects in your foetus and hence is not recommended during pregnancy unless necessary. If you are pregnant consult your doctor.

Breast-feeding

Metox Am (5/25 mg) Tablet passes into breastmilk and may cause side effects in your infant. If you are breastfeeding, consult your doctor.
General warnings

Abrupt withdrawal

Abrupt withdrawal of Metox Am (5/25 mg) Tablet may affect your blood pressure control and may worsen your symptoms. Do not discontinue the use of this medicine without consulting your doctor.

Surgery

Anaesthetic medicines given during surgery may increase your risk of hypotension (low blood pressure). This risk is increased in the presence of Metox Am (5/25 mg) Tablet. Hence treatment with this medicine should be informed to your doctor before scheduling a surgery. Your doctor may consider withdrawal of Metox Am (5/25 mg) Tablet 48 hours before administering anaesthesia.

Other medicines

Metox Am (5/25 mg) Tablet may interact with other medicines and may cause undesired side effects. Inform your doctor about all your current medicines including any herbs or supplements before taking this medicine.

Driving and operating machines

Metox Am (5/25 mg) Tablet may cause dizziness, visual disturbances. Do not drive vehicles or operate machines if you experience any symptoms that may affect your mental alertness.

Use in children

Metox Am (5/25 mg) Tablet is not recommended for use in children and adolescents below 18 years of age because the safety and efficacy data is not available.

Sports

Athletes are advised to avoid participating in high-risk sports such as archery, racing, shooting, etc. during treatment with Metox Am (5/25 mg) Tablet. Sportspersons should refer to the list of medicines published by the World Anti-Doping Agency to get information about the prohibited substances.

Missed Dose

Try not to skip a dose of Metox Am (5/25 mg) Tablet. Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Do not take more doses than what is prescribed by your doctor. Contact your doctor in case of an overdose with Metox Am (5/25 mg) Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended when on treatment with Metox Am (5/25 mg) Tablet as it may lower your blood pressure. You may also experience headaches, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate.
Interaction with Medicine

Corticosteroids

Carbamazepine

Itraconazole

Diltiazem

Rifampicin

Disease interactions

Lung disease

Metox Am (5/25 mg) Tablet is not recommended if you have pre-existing lung problems such as asthma, chronic obstructive pulmonary disease (a condition with swollen air sacs, resulting in breathing difficulties) as it may worsen your breathing problems. If required, your doctor may prescribe the lowest dose possible to avoid worsening your condition.

Diabetes

Metox Am (5/25 mg) Tablet should be used with caution if you have diabetes as this medicine may cause hypoglycaemia (low blood sugar levels). It is recommended to periodically monitor your blood sugar levels.

Liver disease

Metox Am (5/25 mg) Tablet should be used with caution if you have pre-existing liver problems due to the increased risk of serious side effects. Your liver function will be closely monitored and your dose may be adjusted accordingly.

Glaucoma

Glaucoma is a condition where the pressure in the eyeballs is abnormally high that can damage the optic nerve and lead to eventual loss of vision. If you have glaucoma, Metox Am (5/25 mg) Tablet may affect your intraocular pressure and should be used with caution.

Pheochromocytoma

Pheochromocytoma is a condition with a non-cancerous tumour in your adrenal glands (glands located above your kidneys), which results in high blood pressure. Metox Am (5/25 mg) Tablet when given alone in this condition may further increase your blood pressure. Inform your doctor before starting treatment with this medicine. Your doctor may prescribe additional anti-hypertensive medicines to help control your high blood pressure.

Psoriasis

Psoriasis is a chronic (long-term) skin condition that causes a skin rash with red, itchy, scaly patches. Metox Am (5/25 mg) Tablet should be used with caution if you have this condition as it may worsen your skin rash.

Myasthenia Gravis

Myasthenia gravis is a neuromuscular condition that causes weakness in your skeletal muscles (the muscles your body uses for movement). Metox Am (5/25 mg) Tablet should be used with caution if you have this condition as it may worsen your symptoms and cause severe muscle weakness.

Hyperlipidaemia

Hyperlipidaemia is a condition with high blood levels of lipids (fats/cholesterol). Metox Am (5/25 mg) Tablet may alter your blood cholesterol levels. If you have pre-existing hyperlipidaemia, your blood cholesterol levels will be closely monitored and your dose may be adjusted accordingly.

Cardiogenic shock

Metox Am (5/25 mg) Tablet is not recommended for use if you suffer from cardiogenic shock (a life-threatening condition where your heart suddenly stops pumping enough oxygen-rich blood to your body) as it may worsen your condition.

Hyperthyroidism

Use Metox Am (5/25 mg) Tablet with caution if you have hyperthyroidism (high thyroid levels) as it may mask some of your symptoms. Report any unusual symptoms to the doctor immediately. Your doctor may monitor your thyroid levels during the treatment with this medicine. Replacement with a suitable alternative may be required based on your clinical condition.
Food interactions
Do not take Metox Am (5/25 mg) Tablet with grapefruit juice due to the increased risk of severe side effects such as dizziness, headache, swelling of hands and feet, etc.
Multivitamins and mineral supplements may reduce the effectiveness of Metox Am (5/25 mg) Tablet when taken together. It is recommended to take these two medications with a gap of at least two hours.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Metox Am (5/25 mg) Tablet with or without food. Do not stop the use of this medicine without consulting your doctor as it may worsen your condition. Avoid alcohol consumption while on treatment with Metox Am (5/25 mg) Tablet as it may affect your blood pressure. Do not drive vehicles or operate machines if you experience any symptoms that may affect your alertness after taking Metox Am (5/25 mg) Tablet.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Metox Am (5/25 mg) Tablet is a combination of Amlodipine and Metoprolol. Amlodipine works by relaxing the heart muscles and the blood vessels. This helps in lowering blood pressure. Metoprolol relaxes the blood vessels and reduces the heart rate, promotes a smooth flow of the blood, and causes a decrease in blood pressure. This combination is thus effective in reducing blood pressure and the strain on your heart.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Cardioselective beta blockers, Antihypertensive combinations

Schedule

Schedule H

Medicines.org.uk. 2021. Amlodipine 5mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 30 September 2021].

https://www.medicines.org.uk/emc/product/4717/smpc>

Medicines.org.uk. 2021. Metoprolol Tartrate 50 mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 30 September 2021].

https://www.medicines.org.uk/emc/product/5345/smpc>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 30 September 2021].

https://www.medicines.org.uk/emc/files/pil.4717.pdf>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 30 September 2021].

https://www.medicines.org.uk/emc/files/pil.5345.pdf>

Drugs, H., 2021. Amlodipine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 30 September 2021].

https://medlineplus.gov/druginfo/meds/a692044.html>

Drugs, H., 2021. Metoprolol: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 30 September 2021].

https://medlineplus.gov/druginfo/meds/a682864.html>
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Information on this page was last updated on 15 Nov 2021

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