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Monocef 250 MG Injection
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Monocef 250 MG Injection

Manufactured byAristo Pharmaceuticals Pvt. Ltd.
ContainsCeftriaxone
Description
Monocef 250 MG Injection is an antibiotic used to treat bacterial infections affecting the lungs, throat, ears, heart, skin, urinary tract, etc. This medicine kills or stops the growth of bacteria causing the infection. Monocef 250 MG Injection is not effective against infections caused by viruses. Your doctor may advise Monocef 250 MG Injection alone or in combination with other medications to treat bacterial infections. Monocef 250 MG Injection shows side effects that include diarrhoea, pain at the injection site, rashes and alteration of the results of the liver function test. Do not use this medicine if you are previously allergic to it. Contact your doctor if any side effects are seen for a longer period of time. It is one of the effective antibiotics given to infants, children and adults. Monocef 250 MG Injection should not be taken on your own. It is injected into your vein or muscle by your doctor in a hospital or clinic. Your doctor will determine the dose you need each day and how often the injections should be given. Monocef 250 MG Injection may interact with calcium-containing products. Hence, consult your doctor about the use of Monocef 250 MG Injection if you are receiving calcium products. Complete the course of treatment with Monocef 250 MG Injection, as stopping it abruptly can lead to antibiotic resistance. This can cause your symptoms to return.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Monocef 250 MG Injection

Cefast 250 MG Injection
Alkem Laboratories Ltd.
Cefogram 250 MG Injection
Orchid Chemicals & Pharmaceuticals Ltd.
Ciplacef 250 MG Injection
Cipla Ltd.
Gramocef 250 MG Injection
Micro Labs Ltd.
Trusten 250 MG Injection
Zuventus Healthcare Ltd.

Side effects

Major & minor side effects for Monocef 250 MG Injection

  • Black or tarry stools
  • Chills
  • Difficulty or painful urination
  • Headache
  • Diarrhoea
  • Stomach pain
  • Dizziness
  • Acid or sour stomach
  • Weakness
  • Excessive air or gas in stomach
  • Pain at the injection site
  • Rash
  • Abnormal liver function test

Uses of Monocef 250 MG Injection

What is it prescribed for?

  • Bacterial Meningitis
  • Bacterial Septicemia
  • Gonorrhoea
  • Urinary Tract Infection
  • Community-Acquired Pneumonia
  • Bone and joint infections
  • Skin and soft tissue infections
  • Acute bacterial otitis media
  • Pelvic inflammatory disease
  • Intra-abdominal Infections
  • Bacteremia
  • Bronchitis
  • Bacterial endocarditis
  • Lyme disease
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Monocef 250 MG Injection starts immediately after taking the injection.
  • How long do the effects of this medicine last?
    Monocef 250 MG Injection may remain in the body for up to 48 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Monocef 250 MG Injection.
  • Can this medicine be taken during pregnancy?
    Monocef 250 MG Injection may be safe to use in pregnancy to treat bacterial infections. Animal studies indicate no risk to the foetus; however, data on human studies are not available. Therefore, use Monocef 250 MG Injection only upon your doctor's recommendation.
  • Can this medicine be taken while breast-feeding?
    Monocef 250 MG Injection may be passed into human milk in a low amount. Hence, it should only be used only if your doctor prescribes it. If you are using this medicine while breastfeeding, then observe your baby for symptoms such as diarrhoea.

Allergy

Avoid using Monocef 250 MG Injection if you are allergic to it. Inform your doctor if there is any history of allergy to Monocef 250 MG Injection. If you notice any symptoms such as skin rashes, itching/swelling, dizziness, breathing difficulty, etc., inform your doctor and seek immediate medical attention.

Lidocaine

Monocef 250 MG Injection should not be used with lidocaine as a solvent for intravenous injection or infusion. However, lidocaine can be used as a solvent for the intramuscular route of injection for this medicine, despite contraindications.

Calcium-containing products

Monocef 250 MG Injection should not be used in neonates (babies ≤ 28 days) who are receiving calcium-containing intravenous solutions or infusions such as parenteral nutrition because of the risk of accumulation of this medicine with calcium in the lungs and kidneys.
Warnings for special population

Pregnancy

Monocef 250 MG Injection may be safe to use in pregnancy to treat bacterial infections. Animal studies indicate no risk to the foetus; however, data on human studies are not available. Therefore, use Monocef 250 MG Injection only upon your doctor's recommendation.

Breast-feeding

Monocef 250 MG Injection may be passed into human milk in a low amount. Hence, it should only be used only if your doctor prescribes it. If you are using this medicine while breastfeeding, then observe your baby for symptoms such as diarrhoea.
General warnings

Antibiotic resistance

Antibiotic resistance occurs when bacteria develop the ability to defeat the medicine that was intended to kill them. Hence, to avoid such resistance, you should always complete the entire course of treatment with Monocef 250 MG Injection even if you feel better after a few doses.

Diarrhoea

Monocef 250 MG Injection can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor if you experience severe diarrhoea while receiving this medicine.

Haemolytic anaemia

Haemolytic anaemia is a condition in which red blood cells are destroyed faster than they can be made in the body. Haemolytic anaemia due to immune activity has been observed in people receiving Monocef 250 MG Injection. Your doctor will suggest tests to closely monitor your haemoglobin levels. Consult your doctor in case you experience symptoms of anaemia like breathlessness on exertion, fast heartbeat, fatigue and dizziness.

Driving or operating machines

Monocef 250 MG Injection may cause side effects such as dizziness. Thus, it may affect your ability to drive vehicles or operate machines.

Missed Dose

Since Monocef 250 MG Injection is given in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low.

Overdose

Since Monocef 250 MG Injection is given in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amikacin

Furosemide

Probenecid

Cholera Vaccine (live)

Disease interactions

Colitis

Colitis is the inflammation of the large intestine. Monocef 250 MG Injection can kill the helpful bacteria in your stomach or intestine and lead to diarrhoea. Therefore, use Monocef 250 MG Injection with extreme caution if you have any stomach and intestinal problems, particularly colitis, as it may worsen your health condition.

Seizure disorders

Seizure disorder(fits) is a condition due to uncontrolled electrical activity between brain cells that causes temporary abnormalities in muscle tone and movements, behaviour, etc. Avoid using Monocef 250 MG Injection or maintain caution if you have any history of seizure episodes, as it can trigger the condition. Your doctor will adjust the doses or suggest a suitable replacement as required.

Impaired kidney function

Monocef 250 MG Injection is filtered by the kidney and moved out of the body through urine. If you have any medical conditions that affect the kidneys, Monocef 250 MG Injection has to be taken with caution due to the increased risk of kidney damage.

Impaired liver function

Monocef 250 MG Injection may increase liver enzyme levels and cause liver swelling. Hence, maintain caution during treatment with Monocef 250 MG Injection due to the risk of liver damage.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Monocef 250 MG Injection is for parenteral use. It should be given by a qualified healthcare professional in the clinical or hospital setting. Your doctor will determine an appropriate dosage based on your clinical condition. You should not take Monocef 250 MG Injection on your own. Report any undesirable side effects to your doctor promptly.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Monocef 250 MG Injection works by preventing the formation of bacterial cell walls. This helps in stopping the growth and multiplication of bacteria and eventually kills them.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Third generation cephalosporins, Antibiotics

Schedule

Schedule H1

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https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2dd1be9e-74cc-48e8-bf02-f34a78d80fda>

Drugs, H., 2021. Ceftriaxone Injection: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 11 February 2021].

https://medlineplus.gov/druginfo/meds/a685032.html>

Medicines.org.uk. 2021. Ceftriaxone 1 g powder for solution for injection or infusion - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 11 February 2021].

https://www.medicines.org.uk/emc/product/10604/smpc>

Go.drugbank.com. 2021. Ceftriaxone | DrugBank Online. [online] Available at: < [Accessed 23 February 2021].

https://go.drugbank.com/drugs/DB01212>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 11 February 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/065169s022lbl.pdf>

Labeling.pfizer.com. 2021. [online] Available at: < [Accessed 11 February 2021].

http://labeling.pfizer.com/ShowLabeling.aspx?id=7378>
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Information on this page was last updated on 14 Sep 2021

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