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Monotrate 20 MG Tablet
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Monotrate 20 MG Tablet

Manufactured bySun Pharma Laboratories Ltd.
ContainsIsosorbide-5-Mononitrate
Description
Monotrate 20 MG Tablet is an effective medicine to prevent and treat the chest pain (angina) caused due to narrowing of blood vessels that carries blood to the heart. It also decreases the load on the heart ensuring effective pumping of blood.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Monotrate 20 MG Tablet

Isomin 20 MG Tablet
Cipla Ltd.
Isonorm 20 MG Tablet
Lupin Ltd.
Monn 20 MG Tablet
Sun Pharma Laboratories Ltd.
Nitrofix 20 MG Tablet
Micro Labs Ltd.
Vasotrate 20 MG Tablet
Torrent Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Monotrate 20 MG Tablet

  • Bluish discoloration of lips, fingernails, palm, or hands
  • Irregular heartbeat
  • Low blood pressure
  • Dizziness and fainting
  • Headache
  • Nausea or Vomiting
  • Chest pain
  • Difficulty in breathing
  • Difficulty in swallowing
  • Hives and redness of skin
  • Burning, numbness, tingling in the arms and feet
  • Agitation and anxiety
  • Sleeplessnes

Uses of Monotrate 20 MG Tablet

What is it prescribed for?

  • Angina pectoris
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to Isosorbide-5-mononitrate or any other inactive ingredient present in the formulation.

Anemia

This medicine is not recommended for use if you have anemia or low levels of hemoglobin in the blood due to the increased risk of worsening the patient's condition.

Obstructive heart disease

This medicine is not recommended for use if you have a condition where the blood vessels in the heart have blockage due to swelling or narrowing.

Head trauma/ Increased intracranial pressure

This medicine is not recommended for use in patients having a severe head injury or increased intracranial pressure due to the increased risk of worsening of the patient's condition.

Medicine for erectile dysfunction

This medicine is not recommended for use if you are taking medicines for the treatment of erectile dysfunction. One of the most commonly used medicines for this condition is Viagra (sildenafil),
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Other diseases

Report the incidence of all other diseases of the heart, lung, thyroid, kidney, liver etc to the doctor before receiving this medicine. All these conditions should be taken into consideration to ensure safe and effective use of this medicine.

Hypotension

Use of this medicine may cause a fall in blood pressure levels. This risk is especially higher in patients with a history of cardiovascular diseases. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving and operating machinery

This medicine may cause symptoms such as dizziness, visual disturbances, fainting, weakness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during or immediately after receiving this medicine.

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of adverse effects. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Nitrate free interval

The likelihood of development of drug tolerance is very high if this medicine is taken very regularly. A minimal amount of nitrate free time is required to avoid tolerance is 10-12 hr/day. The tolerance developed is in general for nitrates and may affect other medicines containing nitrates (cross-tolerance).

Pediatric use

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for the next scheduled dose.

Overdose

Contact your doctor immediately if an overdose with this medicine is suspected. Symptoms of an overdose may include a severe headache, fever, nausea, vomiting, difficulty in breathing, excessive sweating, etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol during treatment with this medicine may increase the risk of severe side effects. These side effects may include confusion, dizziness, nausea, vomiting, weakness, and fainting. It is advised that you should avoid alcohol and not to perform activities which require high mental alertness like driving a vehicle and operating machinery when taking these medicines together.
Interaction with Medicine

Amitriptyline

Riociguat

Alprazolam

Flurazepam

Baclofen

Alteplase

Disease interactions

Heart Disease

This medicine should be used with caution in patients with a known history of acute myocardial infarction or congestive heart failure due to the increased risk of worsening the patient's condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hypotension

This medicine should be used with caution in patients suffering from hypotension (low blood pressure). Close monitoring of blood pressure levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Glaucoma

This medicine should be used with extreme caution in patients with a history of glaucoma (increased intraocular pressure) due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver diseases due to an increase in the risk of serious adverse effects. Close monitoring of liver function is advised while taking this medicine. Report any symptoms of confusion or jaundice to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Avoid or limit the use of licorice while taking this medicine. The risk of adverse effects is higher while using them together. Contact your doctor if you experience excessive sweating, dizziness, confusion after taking this medicine with licorice.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller quantities than prescribed. Do not discontinue the use of this medicine abruptly. There should be a sufficient time gap between the two dosages.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by relaxing the blood vessels and reducing the strain on the heart.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antianginal agents

Schedule

Schedule H

Isosorbide mononitrate - DrugBank [Internet]. Drugbank.ca. 2020 [cited 24 March 2020]. Available from:

https://www.drugbank.ca/drugs/DB01020

[Internet]. Medicines.org.uk. 2020 [cited 24 March 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.6115.pdf

[Internet]. Medicines.org.uk. 2020 [cited 24 March 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.2697.pdf

[Internet]. Medicines.org.uk. 2020 [cited 24 March 2020]. Available from:

https://www.medicines.org.uk/emc/files/pil.875.pdf

[Internet]. Durbinglobal.com. 2020 [cited 24 March 2020]. Available from:

http://www.durbinglobal.com/assets/images/products/pdf/Ismo_20_PIL.pdf
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Information on this page was last updated on 22 Apr 2020

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