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Myogrel AP 75 Capsule
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Myogrel AP 75 Capsule

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsAspirin (75 mg) + Clopidogrel (75 mg)
Description
Myogrel AP 75 Capsule is a combination of Aspirin and Clopidogrel. It is one of the primarily prescribed medications that prevent clot formation. Myogrel AP 75 Capsule helps in reducing the risk of various heart problems. Myogrel AP 75 Capsule acts as a blood thinner and prevents the formation of blood clots; thus, it promotes the smooth flow of blood. It helps in the treatment of angina pectoris (chest discomfort/pain caused due to insufficient oxygen supply to the heart muscle), heart attack (blockage of heart muscles due to the formation of plaques), and stroke (decreased blood flow to your brain), etc. Myogrel AP 75 Capsule may cause some side effects such as bleeding gums, nosebleeds, bruising, blood in urine, fatigue, headache, dizziness, tiredness, change of taste, stomach discomfort, etc. Since this medication increases the chances of bleeding, you should be careful while using sharp instruments. Do not take this medicine if you are allergic to Aspirin or Clopidogrel. Myogrel AP 75 Capsule can be taken with or without food. For the ease of remembering, take this medicine around the same time every day. Do not stop taking this medicine without consulting your doctor. Myogrel AP 75 Capsule may possibly interact with other medicines. Inform your doctor about any other health issues you have or if you are undergoing any medical treatment before taking this medicine. Consult your doctor before taking this medicine if you are pregnant, planning a pregnancy, or are breastfeeding. It is not recommended for use in children younger than 18 years of age.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Myogrel AP 75 Capsule

Clopilet A 75 Capsule
Sun Pharma Laboratories Ltd.
Ceruvin A Capsule
Sun Pharma Laboratories Ltd.
Clodrel Plus Capsule
Unichem Laboratories Ltd.
CLOPACT A 150 CAPSULE
Ipca Laboratories Pvt. Ltd.

Side effects

Major & minor side effects for Myogrel AP 75 Capsule

  • Diarrhoea
  • Itching
  • Dizziness
  • Nausea or vomiting
  • Muscle pain
  • Heartburn
  • Change in taste
  • Nosebleeds or bleeding of gums
  • Bruising
  • Blood in the urine or stools

Uses of Myogrel AP 75 Capsule

What is it prescribed for?

  • Prevention of heart attack and stroke
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Myogrel AP 75 Capsule to show its effect is about one to two hours.
  • How long do the effects of this medicine last?
    The duration for which Myogrel AP 75 Capsule remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Administration of alcohol and Myogrel AP 75 Capsule may cause liver damage and increase the risk of gastrointestinal bleeding. Hence, you should avoid or limit the intake of alcohol while taking this medication.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Myogrel AP 75 Capsule.
  • Can this medicine be taken during pregnancy?
    Myogrel AP 75 Capsule is not recommended during pregnancy, as it may cause complications in the development of your foetus. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    Myogrel AP 75 Capsule is not recommended if you are breastfeeding as this medicine may pass into your breast milk and affect your baby. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergic reaction

Avoid taking Myogrel AP 75 Capsule if you are allergic to Aspirin, Clopidogrel, or any other inactive ingredients present in this medication. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, hives, itching/swelling (especially of your face/tongue/throat), severe dizziness, difficulty breathing, etc.

Bleeding disorder

Do not use Myogrel AP 75 Capsule if you have a bleeding disorder like peptic ulcer (an open sore that occurs on the inner lining of your stomach and the upper region of your small intestine) or intracranial haemorrhage (bleeding within the brain) as it can cause excess bleeding resulting in the worsening of your condition.

Severe kidney impairment

Myogrel AP 75 Capsule should be used with caution if you have a history of kidney problems. This medicine is excreted through urine. Using this medicine while you have kidney problems will lead to its accumulation. This can cause permanent damage to your kidneys and worsen your condition. Inform your doctor about your kidney problems.

Severe liver impairment

Myogrel AP 75 Capsule is broken down in your liver and excreted through urine. If you have problems with your liver function, this medicine can further worsen it. Hence avoid taking Myogrel AP 75 Capsule if you have liver problems.

Third trimester of Pregnancy

Myogrel AP 75 Capsule is not recommended for use in the third trimester of pregnancy as it may harm your foetus.
Warnings for special population

Pregnancy

Myogrel AP 75 Capsule is not recommended during pregnancy, as it may cause complications in the development of your foetus. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

Myogrel AP 75 Capsule is not recommended if you are breastfeeding as this medicine may pass into your breast milk and affect your baby. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Asthma

Asthma is a condition that affects your airways and causes breathing difficulty. Myogrel AP 75 Capsule has been associated with worsening of asthma symptoms in some instances. Contact your doctor immediately if breathing becomes more difficult after using this medicine. Your doctor may advise you to discontinue this medicine immediately and recommend a suitable alternative.

Use in children

Myogrel AP 75 Capsule is not recommended for use in children below 18 years of age since the safety and efficacy data is not clinically established.

Driving vehicles or operating machines

Myogrel AP 75 Capsule may cause blurred vision and dizziness. Avoid driving vehicles or operating machines if you experience any of these symptoms.

Increased risk of bleeding, bruising, and haematomas

Use of Myogrel AP 75 Capsule may make you bleed easily and bleed more, which could result in bruising and haematomas (collection of blood outside of blood vessels). Consult your doctor if you have any injuries that are bleeding abnormally or if you have any painful bruising.

Surgical or dental procedures

Inform your doctor that you are taking Myogrel AP 75 Capsule before undergoing any surgical or dental procedures. Your doctor will recommend you to stop taking Myogrel AP 75 Capsule at least 24 hours before undergoing any surgical or dental procedure. Your doctor may restart the medicine as soon as your haemodynamic stability is established following the surgical procedure. Your doctor may recommend replacement with a suitable alternative both during the procedure and after the procedure based on your clinical condition.

Missed Dose

Try not to skip a dose of Myogrel AP 75 Capsule. Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed one. Do not double the dose to compensate for a missed one.

Overdose

Do not take more than the dose prescribed by your doctor. Seek emergency medical attention or contact your doctor in case of an overdose of Myogrel AP 75 Capsule.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Administration of alcohol and Myogrel AP 75 Capsule may cause liver damage and increase the risk of gastrointestinal bleeding. Hence, you should avoid or limit the intake of alcohol while taking this medication.
Interaction with Medicine

Corticosteroids

Nonsteroidal anti-inflammatory drugs

Antacids

Amitriptyline

SSRIs

Oral Anti-coagulants drugs

Disease interactions

Gastrointestinal toxicity

The symptoms of gastrointestinal toxicity are nausea, vomiting, diarrhoea, stomach pain, etc. Myogrel AP 75 Capsule may increase the risk of developing stomach discomfort and gastrointestinal bleeding. Use it only upon your doctor’s prescription.

Gout

Myogrel AP 75 Capsule should be used with caution if you have gout as it may increase urate concentrations in your blood and make your condition worse. Your doctor may recommend appropriate dose adjustments or replacement with a suitable alternative based on your clinical condition.

Glucose-6-phosphate dehydrogenase deficiency

Myogrel AP 75 Capsule should be used with caution if you have glucose-6-phosphate dehydrogenase (G6PD) deficiency as it may increase your risk of haemolysis (breakdown or destruction of red blood cells). Your doctor may recommend appropriate dose adjustments or replacement with a suitable alternative based on your clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Myogrel AP 75 Capsule as prescribed by your doctor. It should be taken with or after a meal. Take this medicine at the same time every day for ease of remembering and better compliance. Do not break, chew, or crush the medicine in your mouth. Swallow as a whole with plenty of water. Follow all the instructions given on the prescription label/packing insert. Do not take Myogrel AP 75 Capsule in larger or smaller quantities than prescribed. Report any unusual symptoms to your doctor immediately. Ensure that the treatment course is completed. Your doctor may change your dose based on your clinical condition. Do not stop the use of this medicine without consulting your doctor. Myogrel AP 75 Capsule may cause you to bruise or bleed easily. Try to avoid cutting or injuring yourself. Your doctor may recommend frequent monitoring of your haemoglobin levels to ensure you do not have any internal haemorrhages (bleeding from a ruptured blood vessel). Keep away from the reach of children and pets. Ensure that the unused or expired medicine is properly disposed of.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Aspirin works by preventing the platelets in your blood from clumping and clotting in your arteries and promoting the smooth flow of blood. Clopidogrel works by blocking platelets from sticking together and preventing them from forming harmful clots. Myogrel AP 75 Capsule is thus effective in reducing the strain on your heart and connected blood vessels and the risk of blood clot formation.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antiplatelet agents, Anticoagulants

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Clopidogrel. [online] Available at: < [Accessed 1 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Clopidogrel>

CiplaMed. 2021. CLOPIVAS-AP Tablets. [online] Available at: < [Accessed 1 July 2021].

https://ciplamed.com/content/clopivas-ap-tablets>

Pubchem.ncbi.nlm.nih.gov. 2021. Aspirin. [online] Available at: < [Accessed 1 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Aspirin>

Ema.europa.eu. 2021. SUMMARY OF PRODUCT CHARACTERISTICS - Clopidogrel/Acetylsalicylic acid Zentiva 75 mg/75 mg film-coated tablets. [online] Available at: < [Accessed 31 December 2021].

https://www.ema.europa.eu/en/documents/product-information/clopidogrel/acetylsalicylic-acid-zentiva-previously-duocover-epar-product-information_en.pdf>

Healthdirect.gov.au. 2021. Clopidogrel/Aspirin 75/75 (Apo). [online] Available at: < [Accessed 31 December 2021].

https://www.healthdirect.gov.au/medicines/brand/amt,992821000168102/clopidogrel-aspirin-75-75-apo>
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Information on this page was last updated on 1 Mar 2022

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