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Neksium 40 MG Tablet
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Neksium 40 MG Tablet

Manufactured byAstra Zeneca Pharma India Ltd.
ContainsEsomeprazole
Description
Neksium 40 MG Tablet is an anti-ulcer medicine. It is used to treat stomach and intestinal conditions like peptic ulcers (sores in the lining of your stomach and intestine), esophagitis (swelling of your food pipe), and gastroesophageal reflux disease (a condition in which the stomach acid flows back into your food pipe), etc. It also relieves stress ulcers (sores in the stomach and intestine that may occur due to illness, infections, etc.) and acidity caused due to the intake of painkillers. It works by stopping the excess production of acid in your stomach. Neksium 40 MG Tablet can cause side effects like nausea, vomiting, headache, stomach pain, diarrhoea, etc. Consult your doctor if these side effects remain for a long time or become worse. Neksium 40 MG Tablet should be taken one hour before your meal. Take this medicine at the same time every day to maintain a constant level of Neksium 40 MG Tablet in your blood. Do not stop taking this medicine without consulting your doctor as your symptoms may reappear. Neksium 40 MG Tablet is not recommended for use if you are allergic to it. Inform your doctor if you have liver or kidney problems, or any other health condition. Report all the medicines that you are taking to your doctor as they can interact with this medicine and reduce its effectiveness. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Neksium 40 MG Tablet

Esokem 40 MG Tablet
Alkem Laboratories Ltd.
Esotrax 40 MG Tablet
Cadila Pharmaceuticals Ltd.
Omipure Fast 40 MG Tablet
Mankind Pharmaceuticals Ltd.
Somifiz 40 MG Tablet
Mankind Pharmaceuticals Ltd.
Esoprazole 40 mg Tablet
Wockhardt Ltd.

Side effects

Major & minor side effects for Neksium 40 MG Tablet

  • Headache
  • Nausea or vomiting
  • Excessive gas in stomach
  • Stomach pain
  • Skin rash
  • Difficulty in breathing
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Irregular heartbeat
  • Diarrhoea
  • Decreased appetite
  • Dizziness

Uses of Neksium 40 MG Tablet

What is it prescribed for?

  • Reflux Esophagitis
  • Gastroesophagal Reflux Disease
  • Helicobacter pylori Infection
  • Zollinger-Ellison Syndrome
  • Peptic Ulcer
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    You may start to feel better within 1 hour after taking Neksium 40 MG Tablet.
  • How long do the effects of this medicine last?
    Neksium 40 MG Tablet may remains in your body for an average duration of 9 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Neksium 40 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Neksium 40 MG Tablet is not recommended during pregnancy as not enough studies are done to understand its safety and efficacy. Consult your doctor before taking this medicine if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    It is not known if Neksium 40 MG Tablet passes into breastmilk. Therefore, if you are breastfeeding, consult your doctor to understand the risks and benefits associated with this medicine.

Allergy

Neksium 40 MG Tablet is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice symptoms such as skin rash, itching/swelling of the face/tongue/throat, breathing difficulty, etc.
Warnings for special population

Pregnancy

Neksium 40 MG Tablet is not recommended during pregnancy as not enough studies are done to understand its safety and efficacy. Consult your doctor before taking this medicine if you are pregnant.

Breast-feeding

It is not known if Neksium 40 MG Tablet passes into breastmilk. Therefore, if you are breastfeeding, consult your doctor to understand the risks and benefits associated with this medicine.
General warnings

Hypomagnesaemia

Long-term use of Neksium 40 MG Tablet may result in hypomagnesaemia (low magnesium levels in your blood) due to excess excretion of it through urine. Inform your doctor if you experience symptoms such as dizziness, irregular heartbeat, shivering, muscle pain, seizures (fits). Your doctor may monitor your magnesium levels at regular intervals during treatment with this medicine.

Lupus erythematosus

Lupus erythematosus is an autoimmune disease that affects the skin, kidneys, brain, joints, and other organs. It occurs when the immune system of your body attacks its own tissues. Lupus erythematosus may occur or worsen while using Neksium 40 MG Tablet. Inform your doctor immediately if you experience tiredness, painful joints, rashes, or lesions on the skin while using this medicine.

Vitamin B12 deficiency

Long-term treatment with Neksium 40 MG Tablet may decrease the absorption of Vitamin B12 in your body. Your doctor may prescribe vitamin B12 supplements if this medicine is used for a longer time.

Driving or operating machines

Neksium 40 MG Tablet may cause sleepiness or dizziness. Hence, avoid performing activities such as driving vehicles or operating machines if you experience such symptoms.

Atrophic gastritis

Long-term use of Neksium 40 MG Tablet may cause atrophic gastritis (swelling in the lining of the stomach) Hence, use this medicine only for the prescribed duration.

Missed Dose

If you forget to take Neksium 40 MG Tablet, take it as soon as you remember. If it is time for the next dose then skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention in case of an overdose of Neksium 40 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clopidogrel

Methotrexate

Warfarin

Nelfinavir

Digoxin

Fluconazole

Disease interactions

Liver Disease

Neksium 40 MG Tablet should be used with caution if you have liver problems. Impaired liver function may lead to an increase in the levels of unused medicine in your blood. Your doctor may adjust your dose or suggest another medicine in such cases.

Osteoporosis

Osteoporosis is a condition in which your bones become weak and fragile. Long-term use of Neksium 40 MG Tablet can increase the risk of bone loss. Hence, this medicine should be used with caution if you have osteoporosis. Your doctor may recommend vitamin D and calcium supplements if you have such conditions.

Colitis

Neksium 40 MG Tablet may cause diarrhoea. Take this medicine with extreme caution if you have stomach and intestine problems, particularly colitis (swelling of the inner lining of the colon), as it may cause severe diarrhoea.
Food interactions
Take Neksium 40 MG Tablet at least 1 hour before a meal as food may reduce the absorption of the medicine in your body.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Neksium 40 MG Tablet as instructed by your doctor. Do not break, crush or chew the tablet. Take Neksium 40 MG Tablet for the recommended duration. Avoid taking more or less than the prescribed dose. Avoid spicy and fatty foods, alcohol, and caffeinated drinks or beverages (such as coffee, tea, and cola) while taking this medicine. Consult your doctor if your condition is not improving after few days or if your symptoms are getting worse. Always check the date of expiry before taking this medicine. Throw away the unused medicine safely after it has expired. Keep it away from children and pets.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Neksium 40 MG Tablet decreases the acid production in your stomach. It also fastens the healing process for ulcers.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Proton pump inhibitors, Anti-Ulcer Agents

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Esomeprazole. [online] Available at: < [Accessed 2 March 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Esomeprazole>

Drugs, H., 2021. Esomeprazole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 2 March 2021].

https://medlineplus.gov/druginfo/meds/a699054.html>

Medicines.org.uk. 2021. Esomeprazole 20 mg Gastro-resistant Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 2 March 2021].

https://www.medicines.org.uk/emc/product/10557/smpc>

Dailymed.nlm.nih.gov. 2021. DailyMed - ESOMEPRAZOLE- esomeprazole magnesium tablet. [online] Available at: < [Accessed 15 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ea9ef7b0-7397-470f-b852-397e8b0e66e4>

Astrazeneca.ca. 2021. [online] Available at: < [Accessed 15 September 2021].

https://www.astrazeneca.ca/content/dam/az-ca/downloads/productinformation/nexium-consumer-information-leaflet-en.pdf>
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Information on this page was last updated on 2 Nov 2021

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