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Oflox 400 MG Tablet
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Oflox 400 MG Tablet

Manufactured byCipla Ltd.
ContainsOfloxacin
Description
Oflox 400 MG Tablet is an antibiotic used for the treatment of bacterial infections affecting your lungs, skin, and urinary tract (the kidneys, bladder, ureters, or urethra). It works by stopping the growth of bacteria that causes infection. It is not effective against infections caused by viruses. Oflox 400 MG Tablet can cause side effects like diarrhoea, stomach pain, headache, nausea, and vomiting. Consult your doctor if these side effects persist or become worse. Avoid activities that require mental focus like driving and operating machines as this medicine may cause dizziness. Oflox 400 MG Tablet can be taken with or without food as prescribed by your doctor. Your doctor will determine the dose of this medicine based on your condition. Take this medicine at the same time every day for the ease of remembering. Complete the whole course of treatment for maximum benefit and to prevent the risk of re-infection. Oflox 400 MG Tablet is not recommended for use if you are allergic to it. Avoid taking this medicine if you have tendinitis (a condition that causes swelling of the tissues that attach bones with muscles) or myasthenia gravis (a condition that causes severe weakness of the muscles under voluntary control). Oflox 400 MG Tablet should be used with caution if you have liver or kidney problems. Report all your medicines to your doctor as they may interact with Oflox 400 MG Tablet and cause side effects. If you are pregnant or are breastfeeding, consult your doctor before taking this medicine.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Oflox 400 MG Tablet

Alproxen 400 MG Tablet
Alkem Laboratories Ltd.
Chekmet 400 MG Tablet
Abbott Healthcare Pvt. Ltd.
Eufox 400 MG Tablet
Lupin Ltd.
Mexaflo 400 MG Tablet
Novartis India Ltd.
Oflotas 400 MG Tablet
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Oflox 400 MG Tablet

  • Stomach pain
  • Loose stools
  • Black or Tarry stools
  • Nausea and vomiting
  • Muscle pain
  • Fever
  • Painful urination
  • Decreased appetite
  • Joint pain
  • Change in taste
  • Excessive air or gas in stomach
  • Runny nose
  • Dizziness
  • Skin rash

Uses of Oflox 400 MG Tablet

What is it prescribed for?

  • Urinary tract infection
  • Pyelonephritis
  • Urethritis
  • Cystitis
  • Community-acquired pneumonia
  • Bronchitis
  • Traveller's diarrhoea
  • Skin and soft tissue infections
  • Gonorrhea
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Oflox 400 MG Tablet starts showing its effects within 1-2 hours after taking it.
  • How long do the effects of this medicine last?
    Oflox 400 MG Tablet may remain active in your body for roughly around 2 days.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Oflox 400 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Oflox 400 MG Tablet is not recommended to be used in pregnancy as it may harm your foetus. Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Oflox 400 MG Tablet is present in breast milk. Therefore, it is not recommended to be used while breastfeeding. Consult your doctor before taking it to know all the risks and benefits associated with this medicine.

Allergy

Avoid using Oflox 400 MG Tablet if you are allergic to it. If you notice any allergic reactions like redness, swelling (anywhere in your body), hives (skin rash), breathing difficulty etc., seek immediate medical attention.

Tendinitis or tendon rupture

Oflox 400 MG Tablet can cause muscle damage especially in old age. Do not use Oflox 400 MG Tablet if you have tendonitis (swelling of fibres that attach bone with muscles) or tendon rupture (a partial or complete tear of the tendon- the tissue that connects muscle to bone) as may worsen your condition.

Myasthenia gravis

Myasthenia gravis is a skeletal muscle weakness condition characterized by severe weakness of any of the muscles under your voluntary control like arms and legs. Oflox 400 MG Tablet should be avoided if you have myasthenia gravis as it may worsen your condition.
Warnings for special population

Pregnancy

Oflox 400 MG Tablet is not recommended to be used in pregnancy as it may harm your foetus. Consult your doctor before taking this medicine.

Breast-feeding

Oflox 400 MG Tablet is present in breast milk. Therefore, it is not recommended to be used while breastfeeding. Consult your doctor before taking it to know all the risks and benefits associated with this medicine.
General warnings

Muscle damage

Oflox 400 MG Tablet can cause muscle damage usually on the tendons that surround your ankle. Inform your doctor if you feel pain, numbness, or tingling sensations in your muscles.

Antibiotic resistance

Finish your entire course of treatment with Oflox 400 MG Tablet, even if the condition gets better after taking a few doses to avoid antibiotic resistance (the bacteria may become resistant to antibiotics). If you still feel unwell after completing your antibiotic course, consult your doctor.

Driving or operating machinery

Oflox 400 MG Tablet may cause dizziness or sleepiness and interfere with eyesight. Hence, do not drive vehicles or operate machines after taking this medicine.

Photosensitivity

Oflox 400 MG Tablet may make you more sensitive to sunlight or tanning lights. Use sunscreens or wear protective clothing before stepping outside to avoid undesirable effects.

Diarrhoea

Oflox 400 MG Tablet can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor immediately if you experience severe diarrhoea that is watery or bloody.

Antacids

If you are taking an antacid containing aluminium and magnesium salts for indigestion, it can increase the time takes for Oflox 400 MG Tablet to act on your body. Hence, it is recommended to take this medicine at least 1 hour before or 2 hours after taking antacids.

Missed Dose

Do not skip any dose of Oflox 400 MG Tablet. If you forget to take a dose, take it as soon as you remember. If your next dose time is near, skip the missed dose and take your next scheduled dose. Do not double your dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention if you suspect that you might have taken an overdose of Oflox 400 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Escitalopram

Ethinyl Estradiol

Corticosteroids

Quinidine

Aspirin

Disease interactions

Central nervous system disorders

Take Oflox 400 MG Tablet with caution if you have nerve problems, seizures, depression, and psychotic disorders as it can worsen these conditions. Inform your doctor immediately if these reactions occur.

Colitis

Oflox 400 MG Tablet is used with extreme caution if you have gastrointestinal (stomach and intestines) diseases, particularly colitis (swelling of the inner lining of the colon), as it may worsen your condition.

QT Prolongation

Oflox 400 MG Tablet may cause heart rhythm problems called prolonged QT intervals (an electrical heartbeat disturbance) if you are taking heart medications. It may result in fast, rapid, and irregular heartbeats.

Kidney diseases

Oflox 400 MG Tablet should be taken with caution if you have kidney disease as a damaged kidney may lead to accumulation of this medicine and increases the risk of side effects. Your doctor may adjust the dose of this medicine as needed based on your condition.
Food interactions
Avoid consuming multivitamins with minerals while taking Oflox 400 MG Tablet. If needed it is suggested to take this medicine before 2 to 4 hours or after 4 to 6 hours of taking multivitamins with minerals.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Oflox 400 MG Tablet as instructed by the doctor. Drink plenty of water with it to avoid stomach irritation. Do not crush, break or chew the tablet. Oflox 400 MG Tablet is given for a short period of time. Hence, it is important to complete the whole treatment for maximum benefits. Avoid consuming dairy products and drinking alcohol while taking Oflox 400 MG Tablet as it reduces the efficiency of this medicine. Consult your doctor if your condition is not improving or getting worse after taking few doses of Oflox 400 MG Tablet. Check the expiry date before using Oflox 400 MG Tablet. Throw the unused medicine safely after the expiry date. Keep it away from children and pets.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Oflox 400 MG Tablet works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Fluoroquinolones, Antibiotics

Schedule

Schedule H

Drugs, H., 2021. Ofloxacin: Medlineplus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 6 January 2021].

https://medlineplus.gov/druginfo/meds/a691005.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 6 January 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/019735s059lbl.pdf>

CiplaMed. 2021. OFLOX Tablets. [online] Available at: < [Accessed 7 January 2021].

https://ciplamed.com/content/oflox-tablets>

Medicines.org.uk. 2021. Ofloxacin 200 Mg Tablets - Patient Information Leaflet (PIL) - (Emc). [online] Available at: < [Accessed 6 January 2021].

https://www.medicines.org.uk/emc/product/8481/pil>
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Information on this page was last updated on 7 Oct 2021

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