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Orcerin 50 mg Capsule
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Orcerin 50 mg Capsule

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsDiacerein
Description
Orcerin 50 mg Capsule contains diacerein that is used to relieve pain, stiffness and swelling of joints associated with osteoarthritis. Osteoarthritis is a joint disorder caused when the protective cartilage which acts as a cushion between two ends of bones wears down, leading to joint tenderness and pain with movement. It works by forming a soft connective tissue around the joints (cartilage), thus it relieves pain and swelling at the joints. This medicine is slow acting and is used as a long-term treatment option, either alone or in combination to treat joint pains. Orcerin 50 mg Capsule shows common side effects like diarrhoea and urine discolouration. Usually, these side effects resolve with time. If any of these symptoms persist for a long time or worsen, consult your doctor at the earliest. Inform your doctor if you have medical conditions related to your liver, kidney and heart, diabetes (increased blood sugar levels), etc. before taking this medicine. Inform the doctor if you are pregnant, planning a pregnancy or breastfeeding. Orcerin 50 mg Capsule can be taken with or without food. Take this medicine as directed by your doctor. Do not stop taking it on your own even if you feel better. Along with the medicine, regular exercises to strengthen the muscles around the affected joint and managing the bodyweight should be adopted in daily lifestyle.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Orcerin 50 mg Capsule

Dycerin 50 mg Capsule
Glenmark Pharmaceuticals Ltd.
Kondro Cerin 50 mg Capsule
Panacea Biotec Ltd.
Ostomod 50 mg Capsule
Cipla Ltd.
Vokmor 50 mg Capsule
Intas Pharmaceuticals Ltd.
Zerine 50 mg Capsule
Sanofi India Ltd.

Side effects

Major & minor side effects for Orcerin 50 mg Capsule

  • Diarrhoea
  • Stomach discomfort and pain
  • Nausea
  • Vomiting
  • Urine discoloration
  • Increase in liver enzyme levels
  • Allergic skin reaction

Uses of Orcerin 50 mg Capsule

What is it prescribed for?

  • Osteoarthritis
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The actual time Orcerin 50 mg Capsule takes to show its effect is 2-3 hours.
  • How long do the effects of this medicine last?
    The duration of action of Orcerin 50 mg Capsule is 27 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    Orcerin 50 mg Capsule has no habit forming tendencies.
  • Can this medicine be taken during pregnancy?
    Orcerin 50 mg Capsule is not recommended for use in pregnancy as it may delay the bone formation of your foetus.
  • Can this medicine be taken while breast-feeding?
    Orcerin 50 mg Capsule is known to pass into the breastmilk. This medicine may affect the kidneys and bone growth in infants. Consult your doctor before taking this medicine during breastfeeding.

Allergy

Do not take Orcerin 50 mg Capsule if you have a known allergy to this medicine. Seek medical attention if you notice any allergic reactions such as skin rash, hives (painful, itchy eruptions that sting), swelling (face, lips, tongue, etc.), breathing difficulty, etc.

Kidney diseases

Orcerin 50 mg Capsule is excreted through kidneys. If you have pre-existing kidney disease, this medicine may accumulate in your kidneys and further worsen your condition. Hence, this medicine is not recommended for use if you have kidney problems.
Warnings for special population

Pregnancy

Orcerin 50 mg Capsule is not recommended for use in pregnancy as it may delay the bone formation of your foetus.

Breast-feeding

Orcerin 50 mg Capsule is known to pass into the breastmilk. This medicine may affect the kidneys and bone growth in infants. Consult your doctor before taking this medicine during breastfeeding.
General warnings

Diarrhoea

Orcerin 50 mg Capsule may cause diarrhoea or loose stools in the first few days of treatment. Contact your doctor if the diarrhoea does not stop within 3-4 days.

Antibiotic therapy

Orcerin 50 mg Capsule should not be taken with antibiotics since the risk of stomach irritation and persistent diarrhoea is significantly high.

Diagnostic tests

It is recommended to monitor your liver function, kidney function and complete blood count in every six months during treatment with Orcerin 50 mg Capsule.

Urine discolouration

The use of Orcerin 50 mg Capsule may cause the intense yellow colour of urine. This is mainly due to the excretion of end products and may not lead to any serious side effects.

Missed Dose

If you forget to take a dose of Orcerin 50 mg Capsule, make sure that you remember to take your next dose when it is due. Do not take two doses together to make up for a missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment or contact the doctor if you suspect that you might have taken an overdose of Orcerin 50 mg Capsule.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Amoxycillin

Laxatives

Antacids containing calcium/magnesium/aluminum

Disease interactions

Irritable bowel syndrome

Irritable bowel syndrome (IBS) is an intestinal disorder that causes pain in the abdomen, gases and diarrhoea/constipation. Orcerin 50 mg Capsule may increase the risk of diarrhoea in people having IBS.

Kidney diseases

Orcerin 50 mg Capsule is excreted through kidneys. If you have pre-existing kidney disease, this medicine may accumulate in your kidneys and further worsen your condition. Hence, this medicine is not recommended for use if you have kidney problems.
Food interactions
A diet rich in fibres and phytates (beans, seeds and grains) may interfere with the absorption of Orcerin 50 mg Capsule from the stomach. Hence, taking this medicine with a diet rich in fibres and phytates should be avoided.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Orcerin 50 mg Capsule as instructed by your doctor. You can take this medicine with or without food. Exercise to strengthen muscles around the affected joint and managing your weight while taking this medicine will help you to get better effects. It may increase your blood sugar level. If you are diabetic, monitor your blood sugar levels regularly. Do not take Orcerin 50 mg Capsule if you are suffering from diarrhoea. Let your doctor know if your symptoms do not improve even after two to three months of taking this medicine. Do not break, crush or chew the capsule. Take the capsule immediately after peeling from the strip.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Orcerin 50 mg Capsule works by blocking the actions of a specific protein that causes swelling, pain, and degradation of cartilage at bone joints. It also promotes the formation of cartilage (a soft tissue around the joints), thus relieves discomfort in your physical movements.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Antirheumatics

Schedule

Schedule H

Mims.com. 2021. Diacerein: Indication, Dosage, Side Effect, Precaution | CIMS India. [online] Available at: < [Accessed 27 July 2021].

https://www.mims.com/india/drug/info/diacerein?type=full&mtype=generic>

Data.health.gov.il. 2021. [online] Available at: < [Accessed 13 July 2021].

https://data.health.gov.il/drugs/alonim/Diatrim_dr_1462364199647.pdf>

JP, P., M, Y., B, H., P, C., MA, N., D, C., I, W., IA, R. and AD, B., 2021. Efficacy and safety of diacerein in osteoarthritis of the knee: a double-blind, placebo-controlled trial. The Diacerein Study Group. [online] PubMed. Available at: < [Accessed 13 July 2021].

https://pubmed.ncbi.nlm.nih.gov/11037895/>

Pubchem.ncbi.nlm.nih.gov. 2021. Diacerein. [online] Available at: < [Accessed 13 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/26248>

Data.health.gov.il. 2021. [online] Available at: < [Accessed 28 July 2021].

https://data.health.gov.il/drugs/alonim/Diatrim_dr_1462364199647.pdf>
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Information on this page was last updated on 2 Sep 2021

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