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Pregadoc Plus Capsule
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Pregadoc Plus Capsule

Manufactured byLUPIN LTD
ContainsAlpha lipoic acid (100 mg) + (1.5 mg) + Methylcobalamin (750 mcg) + Pregabalin (75 mg) + Pyridoxine (1.5 mg)
Description
Pregadoc Plus Capsule is a combination of Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Pyridoxine. It is used to treat diabetic neuropathy (a type of nerve damage due to diabetes). This medicine blocks the transfer of pain signals from the damaged nerves. It also helps to repair the damaged nerves. Pregadoc Plus Capsule shows side effects like nausea, vomiting, headache, skin rash, indigestion, etc. These side effects usually subside with time as your body adjusts to the medicine. However, consult your doctor if any of these side effects persist or become severe. Avoid driving vehicles or operating machines if you feel dizzy or drowsy after taking this medicine. Pregadoc Plus Capsule may be taken with or without food as instructed by your doctor. Take this medicine at the same time every day for the ease of remembering. Avoid the discontinuation of this medicine without consulting your doctor as it may worsen your condition. Pregadoc Plus Capsule is not recommended for use if you are allergic to it, or if you have Leber's disease (a rare genetic disorder that occurs due to the death of optic nerve cells in the eyes leading to painless loss of vision). Inform your doctor if you are taking any other medicine, or have any other medical condition before starting the treatment with Pregadoc Plus Capsule. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Pregadoc Plus Capsule

  • Nausea and vomiting
  • Loss of appetite
  • Skin rash
  • Diarrhoea
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Weakness
  • Dry mouth
  • Headache

Uses of Pregadoc Plus Capsule

What is it prescribed for?

  • Diabetic Neuropathy
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time Pregadoc Plus Capsule takes to show show its action is not known.
  • How long do the effects of this medicine last?
    The amount of time for which Pregadoc Plus Capsule remains active in your body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Pregadoc Plus Capsule as it may increase the risk of side effects like drowsiness, dizziness, and difficulty in concentrating. Avoid performing activities that require high mental alertness like driving vehicles or operating machines.
  • Is this a habit forming medicine?
    Pregadoc Plus Capsule has a low abuse potential with limited physical and psychological dependence.
  • Can this medicine be taken during pregnancy?
    Pregadoc Plus Capsule is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Pregadoc Plus Capsule is not recommended for use while breastfeeding as it may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.

Leber's Disease

Leber's disease is a rare genetic disorder in which there is a painless loss of vision due to the death of optic nerve cells in your eyes. Pregadoc Plus Capsule is not recommended if you have Leber's disease as it may worsen your condition.

Allergy

Avoid taking Pregadoc Plus Capsule if you are allergic to it. Seek immediate medical attention if you notice symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Pregadoc Plus Capsule is not recommended for use during pregnancy. Hence, consult your doctor if you are pregnant.

Breast-feeding

Pregadoc Plus Capsule is not recommended for use while breastfeeding as it may pass into breastmilk. Hence, consult your doctor if you are breastfeeding.
General warnings

Other medicines

Pregadoc Plus Capsule may interact with other medicines and cause undesired effects. Hence, inform your doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Gastrointestinal surgery

If you recently had gastrointestinal surgery, it may decrease the absorption of Pregadoc Plus Capsule into the blood. Hence, inform your doctor if you have undergone gastrointestinal surgery before starting treatment with this medicine.

Use of antacids

Coadministration of antacids and Pregadoc Plus Capsule may reduce the absorption of this medicine. Hence, take this medicine one hour before or two hours after taking antacids containing aluminum and magnesium hydroxide.

Kidney disease

Pregadoc Plus Capsule is filtered by the kidneys and removed from the body via urine. Hence, this medicine should be used with caution if you have kidney problems. Impaired kidney function may lead to the accumulation of this medicine in your body and increase the risk of side effects. Your doctor may suggest tests to closely monitor your kidney functions while you are taking this medicine.

Suicidal tendencies

Pregadoc Plus Capsule may lead to change in mood or behaviour and suicidal tendencies. Report any mood changes to your doctor immediately so that counselling can be done. If the symptoms persist, your doctor may advise an alternate medicine.

Driving or operating machines

Pregadoc Plus Capsule may increase the risk of side effects like drowsiness, dizziness, difficulty in concentrating, etc. Hence, avoid performing activities such as driving vehicles or operating machines if you experience any of these symptoms.

High creatinine kinase levels

Myopathy is a condition in which the muscles do not function properly leading to muscle weakness. Pregadoc Plus Capsule should be used with caution in such conditions as this medicine causes an increase in the creatine kinase levels. Thus, it may worsen your condition.

Use in children

Pregadoc Plus Capsule is not recommended for use in children below 18 years of age as the safety and efficacy data are not clinically established.

Potential for abuse

Pregadoc Plus Capsule may cause dependency, especially if you have used other recreational medicines (medicines taken for enjoyment, or leisure purposes, rather than for medical reasons) in the past. Inform your doctor if you had a history of substance abuse before taking this medicine. Your doctor may prescribe a suitable alternative.

Missed Dose

If you forget to take a dose of Pregadoc Plus Capsule, take the missed dose as soon as you remember. However, if it is time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment if you suspect an overdose of Pregadoc Plus Capsule.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Pregadoc Plus Capsule as it may increase the risk of side effects like drowsiness, dizziness, and difficulty in concentrating. Avoid performing activities that require high mental alertness like driving vehicles or operating machines.
Interaction with Medicine

Levodopa

Phenobarbital

Fluorouracil

Phenytoin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Pregadoc Plus Capsule with or without food. Do not break, chew, or crush the capsule. Avoid taking more or less than the prescribed dose. Consult your doctor if you experience any undesired effects that remain for a long time or become severe. Avoid consuming alcohol while you are taking Pregadoc Plus Capsule as it may cause undesired effects.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Pregadoc Plus Capsule is a combination of Alpha Lipoic Acid, Folic Acid, Methylcobalamin, Pregabalin and Pyridoxine. Alpha lipoic acid works by slowing down nerve damage and reducing symptoms like pain, tingling, and pricking in the feet and legs. Folic acid and Pyridoxine are essential for the production of certain vital components that are necessary to maintain normal body functions. Methylcobalamin helps in the production of myelin (a substance that protects the nerve fibres) and helps to heal the damaged nerve cells. Pregabalin acts by reducing certain chemical substances in the brain and interfering with the pain signals travelling through the damaged nerves and the brain. Thus, it relieves pain due to nerve damage.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Gamma-aminobutyric acid analogs, Vitamins

Schedule

Schedule H

Encyclopedia, M. and B12, V., 2021. Vitamin B12: MedlinePlus Medical Encyclopedia. [online] Medlineplus.gov. Available at: [Accessed 6 September 2021].

https://medlineplus.gov/ency/article/002403.htm

Drugs, H., 2021. Pyridoxine: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 6 September 2021].

https://medlineplus.gov/druginfo/meds/a682587.html

Drugs, H., 2021. Folic Acid: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 14 September 2021].

https://medlineplus.gov/druginfo/meds/a682591.html

Drugs, H. and Supplements, H., 2021. Alpha-Lipoic Acid: MedlinePlus Supplements. [online] Medlineplus.gov. Available at: [Accessed 15 September 2021].

https://medlineplus.gov/druginfo/natural/767.html

Pubchem.ncbi.nlm.nih.gov. 2021. Pregabalin. [online] Available at: [Accessed 14 October 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Pregabalin
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Information on this page was last updated on 24 Feb 2023

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