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Rapilif-D 8/0.5 Capsule Combipack
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Rapilif-D 8/0.5 Capsule Combipack

Manufactured byIPCA LABORATORIES PVT LTD
ContainsSilodosin (8 mg) + Dutasteride (0.5 mg)
Description
Rapilif-D 8/0.5 Capsule Combipack is a combination of Silodosin and Dutasteride. It is used to treat the symptoms of benign prostatic hyperplasia (BPH) in men. BPH is a condition that causes enlargement of your prostate gland leading to urinary problems like difficulty in urination, increased frequency, weak urine stream, etc. This medicine works by relaxing the muscles in your urinary bladder, urethra, and prostate. It also blocks the production of a substance (prostate-specific antigen) that causes an enlargement of your prostate. Rapilif-D 8/0.5 Capsule Combipack shows side effects such as headache, dizziness, diarrhoea, stuffy nose, abnormal ejaculation, and decreased sex drive. These side effects usually subside by themselves. However, consult your doctor if they remain for a long time or become severe. Rapilif-D 8/0.5 Capsule Combipack should be taken as instructed by your doctor. Your doctor will determine the dose and duration of treatment based on the severity of your condition. Avoid taking more or less than the prescribed dose. For the ease of remembering and better results, take it at the same time every day. Avoid discontinuing this medicine without your doctor's suggestion, as your symptoms may reappear. Rapilif-D 8/0.5 Capsule Combipack should be avoided if you are allergic to it or have severe liver/kidney problems. Inform your doctor if you have low blood pressure, any other medical conditions, or taking any other medicines before starting the treatment with this medicine. Rapilif-D 8/0.5 Capsule Combipack is not indicated for use in women and children.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Rapilif-D 8/0.5 Capsule Combipack

  • Chills
  • Dizziness
  • Confusion
  • Headache
  • Diarrhoea
  • Stuffy nose
  • Abnormal ejaculation
  • Decreased sexual drive
  • Breast tenderness

Uses of Rapilif-D 8/0.5 Capsule Combipack

What is it prescribed for?

  • Benign prostatic hyperplasia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Rapilif-D 8/0.5 Capsule Combipack to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Rapilif-D 8/0.5 Capsule Combipack remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol while taking Rapilif-D 8/0.5 Capsule Combipack as it may increase the risk of dizziness, headache, lightheadedness, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Rapilif-D 8/0.5 Capsule Combipack.
  • Can this medicine be taken during pregnancy?
    Rapilif-D 8/0.5 Capsule Combipack is not intended for use in women.
  • Can this medicine be taken while breast-feeding?
    Rapilif-D 8/0.5 Capsule Combipack is not intended for use in women.

Allergy

Avoid taking Rapilif-D 8/0.5 Capsule Combipack if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Severe kidney impairment

Rapilif-D 8/0.5 Capsule Combipack is filtered from your body by the kidneys via urine. Hence, this medicine is not recommended for use if you have severe kidney problems. It may lead to the accumulation of this medicine in your body and increase the risk of side effects.

Severe liver impairment

Rapilif-D 8/0.5 Capsule Combipack is broken down in your liver. Hence, this medicine is not recommended for use if you have severe liver problems as it may cause further liver damage.

Women and children

Rapilif-D 8/0.5 Capsule Combipack is not indicated for use in women and children.
Warnings for special population

Pregnancy

Rapilif-D 8/0.5 Capsule Combipack is not intended for use in women.

Breast-feeding

Rapilif-D 8/0.5 Capsule Combipack is not intended for use in women.
General warnings

Cataract surgery

Cataract surgery is an eye surgery performed to replace the lens in your eyes with an artificial lens to correct the blurring of vision. Rapilif-D 8/0.5 Capsule Combipack may lead to complications during cataract surgery. Hence, if you are taking this medicine, inform your doctor before undergoing surgery.

Low blood pressure

Rapilif-D 8/0.5 Capsule Combipack may cause dilation of your blood vessels and lead to a decrease in blood pressure. Hence, this medicine should be used with caution if you have low blood pressure.

Blood donation

It is not recommended to donate blood until 6 months have passed after taking the last dose of Rapilif-D 8/0.5 Capsule Combipack. This measure is taken to prevent the transfusion of blood to pregnant women.

Other medicines

Inform your doctor if you are taking any other medicines as they may interact with Rapilif-D 8/0.5 Capsule Combipack and cause undesired effects.

Use in women and children

Rapilif-D 8/0.5 Capsule Combipack is not indicated for use in women and children.

Driving or operating machines

Rapilif-D 8/0.5 Capsule Combipack may cause a decrease in blood pressure leading to symptoms like dizziness. Avoid performing activities that require high mental alertness like driving vehicles or operating machines if you experience any symptoms during treatment with this medicine.

Missed Dose

If you miss a dose of Rapilif-D 8/0.5 Capsule Combipack, take it as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose of Rapilif-D 8/0.5 Capsule Combipack. Seek emergency medical treatment in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol while taking Rapilif-D 8/0.5 Capsule Combipack as it may increase the risk of dizziness, headache, lightheadedness, etc.
Interaction with Medicine

Amitriptyline

Ciprofloxacin

Alprazolam

Nefazodone

Clotrimazole

Erythromycin

Itraconazole

Baclofen

Diltiazem

Chlordiazepoxide

Nelfinavir

Conivaptan

Disease interactions

Kidney Disease

Rapilif-D 8/0.5 Capsule Combipack should be used with caution if you have mild to moderate kidney problems as it may increase the risk of side effects. Your doctor may suggest tests to periodically monitor your kidney function and recommend dose adjustments based on your clinical condition.

Liver Disease

Rapilif-D 8/0.5 Capsule Combipack should be used with caution if you have mild to moderate liver problems as this medicine may cause further liver damage. Your doctor may suggest tests to periodically monitor your liver function while taking this medicine.

Prostate cancer

Cancer of the prostate gland has similar symptoms to Benign Prostatic Hyperplasia. Hence, it is important to know if you have prostate cancer before starting the treatment. Your doctor may suggest tests to rule out the presence of prostate cancer before starting the treatment with Rapilif-D 8/0.5 Capsule Combipack.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Rapilif-D 8/0.5 Capsule Combipack as instructed by your doctor. Take this medicine for the recommended duration. Avoid taking more than the prescribed dose as it may increase the risk of side effects. Consult your doctor if your symptoms do not improve or become worse. Avoid blood donation until 6 months of taking the last dose of Rapilif-D 8/0.5 Capsule Combipack to prevent the transfusion of blood to pregnant women.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Rapilif-D 8/0.5 Capsule Combipack is a combination of Silodosin and Dutasteride. Silodosin works by relaxing the muscles of your bladder neck, urethra, and prostate. Thus, it relieves the symptoms of BPH. Dutasteride blocks the production of a substance (Prostate-Specific Antigen (PSA)) that causes an enlargement of your prostate.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Alpha-blockers, 5-alpha-reductase inhibitors, Genitourinary tract agents

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - DUTASTERIDE capsule. [online] Available at: < [Accessed 29 November 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e537c60d-9ba2-4e7f-a405-2b915dcd7ead>

Drugs, H., 2021. Silodosin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 29 November 2021].

https://medlineplus.gov/druginfo/meds/a609002.html>

CiplaMed. 2021. SILOFAST D Tablets. [online] Available at: < [Accessed 6 September 2021].

https://www.ciplamed.com/content/silofast-d-tablets>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 6 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/022206s012lbl.pdf>

Allergan-web-cdn-prod.azureedge.net. 2021. [online] Available at: < [Accessed 6 September 2021].

https://allergan-web-cdn-prod.azureedge.net/allergancanadaspecialty/allergancanadaspecialty/media/actavis-canada-specialty/en/products/pms/rapaflo-pm_eng-12march2018.pdf>
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Information on this page was last updated on 29 Nov 2021

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