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Sibofix 200 MG Tablet
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Sibofix 200 MG Tablet

Manufactured byDr. Reddys Laboratories Ltd.
ContainsRifaximin
Description
Sibofix 200 MG Tablet is an antibiotic used to treat bacterial infections. The lower dose (200mg, 400mg) is used to treat traveller's diarrhoea (an intestinal infection that occurs as a result of eating contaminated food or drinking contaminated water while travelling) caused due to E. coli bacteria. The higher dose (550mg) is used to treat hepatic encephalopathy (a decline in brain function that occurs due to the build-up of toxins in the blood as a result of severe liver disease) and irritable bowel syndrome (a gastrointestinal disorder that leads to pain in the abdomen and changes in bowel movements). Sibofix 200 MG Tablet works by stopping the growth of bacteria. Sibofix 200 MG Tablet can cause side effects like nausea, headache, flatulence (excessive gas in the stomach), swelling of the hands or feet, tiredness, abnormal liver function tests, etc. Consult your doctor if these side effects bother you for a long time or become worse. Avoid driving vehicles or operating machines as this medicine may make you feel dizzy. Sibofix 200 MG Tablet may be taken with or without food. Take it at the same time every day to maintain a constant level of medicine in your body. Ensure that you complete the course treatment to prevent the risk of re-infection and antibiotic resistance (bacteria develop the ability to defeat the medicine that was intended to kill them). Sibofix 200 MG Tablet is not recommended for use if you are allergic to it. Inform your doctor about your current medications and pre-existing medical conditions before taking this medicine. This will help your doctor adjust the dose to avoid any side effects. If you are pregnant or are breastfeeding, consult your doctor before taking Sibofix 200 MG Tablet.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Sibofix 200 MG Tablet

Ciboz 200 MG Tablet
Zydus Cadila
Rcifax 200 MG Tablet
Lupin Ltd.
Rifabet 200 MG Tablet
Fdc Ltd.
Rifagut 200 MG Tablet
Sun Pharma Laboratories Ltd.
Rifnim 200 MG Tablet
Wockhardt Ltd.

Side effects

Major & minor side effects for Sibofix 200 MG Tablet

  • Black or Tarry stools
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Diarrhoea
  • Nausea and vomiting
  • Headache
  • Ringing or buzzing in the ears
  • Excessive air or gas in stomach
  • Muscle and joint pain
  • Blurred vision
  • Dry mouth
  • Dizziness
  • Tiredness
  • Swelling of hands and feet

Uses of Sibofix 200 MG Tablet

What is it prescribed for?

  • Traveller's diarrhoea
  • Hepatic encephalopathy
  • Irritable bowel syndrome
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time taken by Sibofix 200 MG Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The time duration for which Sibofix 200 MG Tablet remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Sibofix 200 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Sibofix 200 MG Tablet is not recommended for use in your pregnancy as limited safety information is available. Hence, consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    It is not known whether Sibofix 200 MG Tablet passes into the breastmilk. Hence, it is not recommended for use while breastfeeding unless necessary. Consult your doctor before taking this medicine.

Allergy

Avoid taking Sibofix 200 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.
Warnings for special population

Pregnancy

Sibofix 200 MG Tablet is not recommended for use in your pregnancy as limited safety information is available. Hence, consult your doctor before taking this medicine.

Breast-feeding

It is not known whether Sibofix 200 MG Tablet passes into the breastmilk. Hence, it is not recommended for use while breastfeeding unless necessary. Consult your doctor before taking this medicine.
General warnings

Traveller's diarrhoea caused by other bacteria

Sibofix 200 MG Tablet is reported to be effective to treat traveller's diarrhoea caused by E. coli bacteria. It is not recommended to take this medicine for traveller's diarrhoea caused by other bacteria.

Clostridium difficile-associated diarrhoea

Sibofix 200 MG Tablet can cause diarrhoea because it may also kill the helpful bacteria in your stomach or intestine. Inform your doctor if you experience severe diarrhoea while taking this medicine.

Antibiotic resistance

Antibiotic resistance occurs when bacteria develop the ability to defeat the medicine that was intended to kill them. Hence, finish your entire course of treatment with Sibofix 200 MG Tablet even if your condition gets better after a few doses to avoid antibiotic resistance.

Driving or operating machines

Sibofix 200 MG Tablet may cause dizziness. Hence, avoid driving vehicles or operating machines if you feel dizzy after taking this medicine.

Use in children

Sibofix 200 MG Tablet is not recommended for use in children below 18 years for the treatment of hepatic encephalopathy and irritable bowel syndrome and in children below 12 years of age for the treatment of traveller's diarrhoea.

Kidney problems

Due to the lack of safety data, Sibofix 200 MG Tablet should be used with caution if you have kidney problems. Consult your doctor before taking this medicine.

Missed Dose

Try not to skip a dose of Sibofix 200 MG Tablet. If you miss a dose, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose. Do not take a double dose to make up for the missed one.

Overdose

Never take more than the prescribed dose. Seek emergency medical attention in case of an overdose with Sibofix 200 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Warfarin

Cyclosporine

Live cholera vaccine

Anisindione

Disease interactions

Colitis

Sibofix 200 MG Tablet can kill the helpful bacteria in your stomach or intestine and cause diarrhoea. Therefore use Sibofix 200 MG Tablet with extreme caution if you have stomach and intestinal problems, particularly colitis (swelling of the inner lining of the large intestine), as it may further worsen your condition.

Liver Disease

Sibofix 200 MG Tablet is broken down in the liver. Hence, it should be used with caution if you have severe liver problems.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Sibofix 200 MG Tablet with or without food. Do not break, chew, or crush the tablet in your mouth. Swallow as a whole with plenty of water. Follow all the instructions given on the prescription label/packing insert. Do not take more or less than the recommended dose of Sibofix 200 MG Tablet. Take this medicine for the recommended duration to avoid the risk of re-infection that would be difficult to treat in the future. Take Sibofix 200 MG Tablet at the same time every day for the ease of remembering. Consult your doctor immediately if you experience any side effects that persist or worsen. Keep this medicine away from the reach of children and pets. Ensure that the unused or expired medicine is disposed of properly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Sibofix 200 MG Tablet works by stopping the growth of bacteria and preventing the spread of infections.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous antibiotics

Schedule

Schedule H

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https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c5e8e2fd-7087-4b78-9181-cc259c0be2f1>

Drugs, H., 2021. Rifaximin: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 2 March 2021].

https://medlineplus.gov/druginfo/meds/a604027.html>

Medicines.org.uk. 2022. XIFAXANTA 200 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 5 April 2022].

https://www.medicines.org.uk/emc/product/4752/smpc>
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Information on this page was last updated on 6 Apr 2022

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