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Sizodon Plus Tablet
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Sizodon Plus Tablet

Manufactured bySUN PHARMA LABORATORIES LTD
ContainsRisperidone (3 mg) + Trihexyphenidyl (2 mg)
Description
Sizodon Plus Tablet is a combination medicine which may be used for the treatment of Schizophrenia and other mood disorders. It also helps in treating the extrapyramidal symptoms. This medicine should be taken regularly in prescribed timings. This medicine is not recommended for use in patients below 18 years of age. Do not stop taking this medicine suddenly as it may cause withdrawal symptoms.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Sizodon Plus Tablet

  • Abdominal pain
  • Constipation
  • Dry mouth
  • Loss of appetite
  • Difficulty in passing urine
  • Skin rash
  • Dizziness
  • Nausea and Vomiting
  • Nervousness
  • Aggression or anger
  • Loss of balance control
  • Changes in vision
  • Back pain
  • Changes in pattern of speech
  • Confusion
  • Weight gain
  • Body pain
  • Decrease in libido

Uses of Sizodon Plus Tablet

What is it prescribed for?

  • Schizophrenia
  • Bipolar disorder
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 6-12 hours in extensive metabolizers and 1-2 days in poor metabolizers.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while receiving this medicine as it may increase the risk of adverse effects like dizziness, difficulty in concentrating, etc. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Narrow angle glaucoma

This medicine is not recommended for use in patients with narrow-angle glaucoma due to the increased risk of worsening of the patient's condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to risperidone, trihexyphenidyl, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Dementia- related psychosis

This medicine is not recommended for use in patients with dementia-related psychosis due to the increased risk of death.

Neuroleptic Malignant Syndrome

Use of this medicine may increase the risk of Neuroleptic Malignant Syndrome in some patients which is characterized by an increase in body temperature, muscle rigidity, altered consciousness. Patients are advised to discontinue the treatment with this medicine in such cases. An alternative treatment option should be considered based on the clinical condition.

Diabetes and Dyslipidemia

Use of this medicine may increase the blood glucose levels and lipids levels in the body. Assess these parameters before initiation of the treatment and regular monitoring of blood glucose and body weight is necessary.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Use in Elderly

This medicine should be used with caution in elderly patients due to the increased risk of orthostatic hypotension and kidney injury. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Drug Withdrawal

Abrupt discontinuation of this medicine may increase the risk of adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Driving or Operating machinery

Use of this medicine may cause blurred vision or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving this medicine as it may increase the risk of adverse effects like dizziness, difficulty in concentrating, etc. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Atenolol

Clobazam

Clozapine

Tramadol

Antidiabetic medicines

Levodopa

Potassium Chloride

Disease interactions

Gastrointestinal blockage

This medicine is not recommended for use in patients with gastrointestinal diseases due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered in some cases based on the clinical condition.

Urinary tract obstruction

This medicine is not recommended for use in patients with urinary tract obstruction due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of adverse effects. Close monitoring of the liver function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of adverse effects. Close monitoring of the kidney function is necessary for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Dementia

This medicine is not recommended for use in patients with dementia-related psychosis as it may increase the risk of heart failure or infectious diseases like pneumonia. This risk is especially high in elderly patients. An alternative treatment option should be considered based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take medicine with or without food. Do not take in larger amounts than advised. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine without consulting your doctor as it may cause withdrawal symptoms.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This combination medicine binds to the receptors and inhibits the release of chemical substances that causes mood disorder and also improves the muscle movement.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Atypical antipsychotics, Anticholinergic antiparkinson agents

Schedule

Schedule H

RISNIA PLUS/RISNIA FORTE Tablets [Internet]. CiplaMed. 2018 [cited 14 August 2018]. Available from:

https://ciplamed.com/content/risnia-plusrisnia-forte-tablets

Trihexyphenidyl - DrugBank [Internet]. Drugbank.ca. 2017 [cited 14 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB00376

DailyMed - RISPERIDONE- risperidone tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 14 August 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1c3250f3-d291-4280-97d5-da3bb171e2b6#section-2
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Information on this page was last updated on 7 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.