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Tenoclor 50 Tablet

Manufactured byABBOTT HEALTHCARE PVT LTD
ContainsAtenolol (50 mg) + Chlorthalidone (12.5 mg)
Description
Tenoclor 50 Tablet is a combination medicine used for the treatment of high blood pressure. Frequent monitoring of blood pressure and electrolytes level is necessary during treatment with this medicine. Patients are advised to follow a strict exercise and diet regimen along with this medicine to get the best possible effect.

Side effects

Major & minor side effects for Tenoclor 50 Tablet

  • Blurred vision
  • Difficulty in breathing
  • Sweating
  • Cold hands or feet
  • Anxiety
  • Chest pain
  • Dizziness
  • Decrease in frequency of urination
  • Increased thirst
  • Loss of appetite
  • Trouble sleeping
  • Diarrhea
  • Very low blood pressure
  • Photosensitivity
  • Constipation
  • Nausea or vomiting
  • Headache

Uses of Tenoclor 50 Tablet

What is it prescribed for?

  • Essential hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 to 72 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, fainting, a very low blood pressure, changes in pulse rate, etc. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to chlorthalidone, other sulfonamides, atenolol, other beta-blockers, or any other inactive ingredients present in the formulation.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock due to the increased risk of worsening of the patient's condition.

Heart block greater than first degree

This medicine is not recommended for use in patients with a heart block greater than first degree due to the increased risk of worsening of the patient's condition.

Sinus Bradycardia

This medicine is not recommended for use in patients with Sinus bradycardia since it may worsen the patient's condition.

Uncompensated cardiac failure

This medicine is not recommended for use in patients with an uncompensated cardiac failure since it may worsen the patient's condition.

Severe pulmonary edema

This medicine is not recommended for use in patients suffering from a severe pulmonary edema due to the increased risk of serious adverse effects.

Anuria

This medicine is not recommended for use in patients with anuria, a condition where the kidney is unable to produce urine.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver impairment due to the increased risk of serious adverse effects.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment (CrCl < 30 ml/min) due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Heart failure

This medicine can cause heart failure and reduced blood flow in patients having a heart disease. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Major surgery

This medicine should be used with caution in patients who are scheduled for a major surgery. An anesthetic agent with little negative inotropic activity should be selected to minimize the effect on the heart.

Lung Disease

This medicine should be used with caution in patients with lung diseases who do not respond to other antihypertensive medications. Start with the lowest possible dose and increase the dose based on the clinical condition. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Sports

Athletes are advised not to indulge in certain sports while using this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency (WADA) which are not to be taken while participating in specific sports events.

Hyperthyroidism

This medicine should be administered with caution in patients with increased thyroid levels. Abrupt withdrawal of this medicine may lead to a life-threatening condition called thyroid-storm. Frequent monitoring of thyroid hormone levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver diseases due to an increase in the risk of serious adverse effects. Close monitoring of liver function is advised while taking this medicine. Report any symptoms of confusion or jaundice to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Volume and electrolyte disturbances

This medicine may alter the blood volume and electrolyte levels in some patients. This may cause dizziness, dry mouth, and acid-base imbalance. This risk is especially higher in patients suffering from kidney and liver diseases. Close monitoring of blood pressure and electrolyte levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with a known history of renal diseases due to the increased risk of worsening of the patient's condition. Close monitoring of renal function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving or operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery during treatment with this medicine if you experience any of these symptoms.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, fainting, a very low blood pressure, changes in pulse rate, etc. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Insulin

Alprazolam

Ziprasidone

Amiodarone

Cisapride

Theophylline

Diltiazem

Lithium

Diclofenac

Disease interactions

Asthma

This medicine is not recommended for use in patients with a history of asthma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Bradyarrhythmia/ AV Block

This medicine is not recommended for use in patients with Sinus Bradyarrhythmia or a heart block greater than the first degree due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.

Glaucoma

This medicine should be used with caution in patients with glaucoma because it may lower the intraocular pressure and worsen the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Diabetes

This medicine should be used with extreme caution in patients suffering from diabetes mellitus due to the increased risk of altered blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Pheochromocytoma

This medicine should be used with caution in patients with pheochromocytoma due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative should be considered under your doctor's supervision.

Hyperuricemia

This medicine should be used with caution in patients with hyperuricemia since this medicine decreases the uric acid excretion. This may cause serious side effects. Appropriate dose adjustments or replacement with a suitable alternative should be done under your doctor's supervision.

Hyperlipidemia

This medicine should be used with caution in patients with hyperlipidemia since it may increase the cholesterol and triglyceride levels. Close monitoring of cholesterol and triglyceride levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Coadministration of multivitamin with minerals and this combination medicine should be avoided since it may decrease the effects of the medicine. A time gap of at least 2 hours should be maintained between the administration of multivitamin with minerals and this combination medicine to avoid their interaction.
Avoid consumption of large amounts of orange juice with this medicine since it may decrease the effectiveness of this medicine.
Lab interactions
Information not available.
Take this medicine exactly as advised by your doctor. Do not take in larger or smaller amounts than prescribed. It is advised to take this medicine at daytime to prevent sleep disturbance. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. Report any adverse effects to the doctor on priority. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Atenolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of blood. Chlorthalidone increases the excretion of water and sodium from the kidneys. Their combination is thus effective in reducing the blood pressure.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Cardioselective beta blockers with thiazides, Antihypertensive combinations

Schedule

Schedule H

[Internet]. Dailymed.nlm.nih.gov. 2019 [cited 5 April 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=4c7b43e9-d6f1-45e6-5699-5f5f2d075449&type=display

[Internet]. Drugbank.ca. 2019 [cited 5 April 2019]. Available from:

https://www.drugbank.ca/drugs/DB00310

[Internet]. Medlineplus.gov. 2019 [cited 5 April 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a682342.html

[Internet]. Medicines.org.uk. 2019 [cited 5 April 2019]. Available from:

https://www.medicines.org.uk/emc/medicine/25739

[Internet]. Medicines.org.uk. 2019 [cited 5 April 2019]. Available from:

https://www.medicines.org.uk/emc/files/pil.8018.pdf
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Information on this page was last updated on 19 Apr 2019

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