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Topamac 50 MG Tablet
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Topamac 50 MG Tablet

Manufactured byJanssen India
ContainsTopiramate
Description
Topamac 50 MG Tablet is a medicine used in the treatment of seizures (sudden, uncontrolled electrical disturbances in the brain causing abnormal behaviour and loss of consciousness). It is also used to prevent migraine headaches. Topamac 50 MG Tablet works by reducing the abnormal electrical activity in the brain. Topamac 50 MG Tablet may cause side effects like nausea, vomiting, fatigue, weight loss, blurred vision, etc. Consult your doctor if these symptoms persist or become severe. Avoid driving vehicles and operating machines as this medicine may cause dizziness or drowsiness. Topamac 50 MG Tablet may be taken with or without food as directed by your doctor. The dose and duration of treatment will be decided by your doctor based on the severity of your condition. Take this medicine for the recommended duration for better results. Avoid abrupt discontinuation of this medicine without consulting your doctor, as it may cause an increased frequency of seizures. Your doctor may withdraw the medicine gradually over a period to avoid such undesired effects. Topamac 50 MG Tablet is not recommended for use if you are allergic to it. Inform your doctor if you have blood disorders, depression, liver or kidney problems, or any other medical conditions before taking this medicine. Inform your doctor about all your current medications to avoid any undesired effects. Consult your doctor if you are pregnant, planning a pregnancy, or are breastfeeding before taking this medication.
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Side effectsConcernsUsageRelated products

Substitutes

List of substitutes for Topamac 50 MG Tablet

Topamate 50 MG Tablet
Cipla Ltd.
Topaz 50 MG Tablet
Intas Pharmaceuticals Ltd.
Topirain 50 MG Tablet
Unichem Laboratories Ltd.
Topiram 50 MG Tablet
Zydus Cadila
Urate 50 MG Tablet
Usv Ltd.

Side effects

Major & minor side effects for Topamac 50 MG Tablet

  • Blurred vision
  • Dizziness
  • Unusual tiredness and weakness
  • Stomach pain
  • Loss of appetite
  • Back pain
  • Constipation
  • Drowsiness
  • Memory problems
  • Changes in menstrual cycle
  • Confusion
  • Weight loss
  • Chills and fever
  • Nausea
  • Decrease in sexual drive
  • Difficulty or painful urination
  • Skin rash or itching

Uses of Topamac 50 MG Tablet

What is it prescribed for?

  • Seizures
  • Lennox-Gastaut Syndrome
  • Migraine Headache
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Topamac 50 MG Tablet to show its action is not clinically established.
  • How long do the effects of this medicine last?
    Topamac 50 MG Tablet may remain in your body for approximately 5 days.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Topamac 50 MG Tablet due to the increased risk of side effects such as dizziness, difficulty in concentration, impaired judgment, etc.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Topamac 50 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Topamac 50 MG Tablet is unsafe for use during pregnancy as it may harm your developing foetus. Hence, consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Topamac 50 MG Tablet may pass into the breastmilk. Hence it is not recommended for use while breastfeeding unless necessary. Consult your doctor if you are breastfeeding.

Allergy

Avoid taking Topamac 50 MG Tablet if you are allergic to this medicine. Seek medical attention if you experience symptoms such as a skin rash, hives (itchy, painful eruptions that sting), swelling (especially of your face, lips, tongue, etc.), breathing difficulty, etc.
Warnings for special population

Pregnancy

Topamac 50 MG Tablet is unsafe for use during pregnancy as it may harm your developing foetus. Hence, consult your doctor if you are pregnant.

Breast-feeding

Topamac 50 MG Tablet may pass into the breastmilk. Hence it is not recommended for use while breastfeeding unless necessary. Consult your doctor if you are breastfeeding.
General warnings

Withdrawal symptoms

Avoid abrupt discontinuation of Topamac 50 MG Tablet may cause increased seizure frequency. Therefore, the treatment should be withdrawn gradually over a period under the close supervision of your doctor. Do not stop the use of this medicine without consulting your doctor.

Suicidal tendency

Topamac 50 MG Tablet should be used with caution as it may increase the risk of depression and suicidal thoughts or behaviour. Consult your doctor immediately if you experience changes in mood and behaviour or develop thoughts of self-harm while taking this medicine.

Driving or operating machines

Topamac 50 MG Tablet may cause dizziness, drowsiness, or blurred vision. Avoid performing activities that require mental alertness, such as driving vehicles or operating machines, if you experience such symptoms.

Metabolic acidosis

Topamac 50 MG Tablet should be used with caution if you have metabolic acidosis (a condition that occurs when the body produces too much acid or when the kidneys are unable to remove enough acid from the body) due to the increased risk of worsening of your condition.

Missed Dose

Take the missed dose of Topamac 50 MG Tablet as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose of Topamac 50 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Topiramate, when coadministered with other CNS depressants including alcoholic beverages, may lead to excessive somnolence and other forms of nervous system depression.

Instructions

Consumption of alcohol is not recommended during treatment with Topamac 50 MG Tablet due to the increased risk of side effects such as dizziness, difficulty in concentration, impaired judgment, etc.
Interaction with Medicine

Amitriptyline

Clozapine

Escitalopram

Metformin

Atropine

Buprenorphine

Clonidine

Amoxapine

Codeine

Cetirizine

Clobazam

Baclofen

Asenapine

Aripiprazole

Perampanel

Oxazepam

Disease interactions

Blood disorders

Bone marrow suppression is a condition in which there is decreased production of blood cells in your bone marrow (a spongy substance present at the centre of your bones). Topamac 50 MG Tablet may cause a decrease in blood cell counts. Hence, it should be used with caution in bone marrow suppression. Your doctor may suggest blood tests to monitor your blood cell counts during treatment with this medicine.

Severe liver impairment

Topamac 50 MG Tablet should be used with extreme caution if you have liver problems as it may further worsen your condition. Your doctor may suggest tests to periodically monitor your liver function and recommend dose adjustments or replacements with a suitable alternative based on your clinical condition.

Kidney dysfunction

Topamac 50 MG Tablet is filtered by the kidneys and removed from the body via urine. Hence, it should be used with caution if you have kidney problems. An impaired kidney function may cause an accumulation of this medicine in the body and increase the risk of undesired effects. Your doctor may adjust the dose of this medicine based on your condition.

Angle Closure Glaucoma

Angle Closure Glaucoma is a condition that develops when the drainage angle (a structure inside the eye that allows the draining of the fluid from the eye) gets blocked. This may cause an increase in fluid pressure inside the eyes and lead to vision loss. Topamac 50 MG Tablet may cause angle-closure glaucoma with symptoms such as decreased clearness of vision, eye pain, increased pressure within the eyes, etc. Hence, Topamac 50 MG Tablet should be used with extreme caution if you have conditions that may cause increased fluid pressure within the eyes, as this medicine may further worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Topamac 50 MG Tablet with or without food. Do not break, chew, or crush the tablet in your mouth. Swallow as a whole with plenty of water. Follow all the instructions given on the prescription label/packing insert. Do not take more or less than the recommended dose of Topamac 50 MG Tablet. Take this medicine for the recommended duration. Do not discontinue this medication abruptly without consulting your doctor. Take Topamac 50 MG Tablet at the same time every day for the ease of remembering. Consult your doctor immediately if you experience any changes in mood and behaviour or thoughts of self-harm. Keep this medicine away from the reach of children and pets. Ensure that the unused or expired medicine is disposed of properly.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Topamac 50 MG Tablet works by increasing the release of inhibitory chemicals which decreases the excitability of the brain cells.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Carbonic anhydrase inhibitor anticonvulsants, Antimigraine agents

Schedule

Schedule H

Medicines.org.uk. 2022. Topamax 200mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 2 February 2022].

https://www.medicines.org.uk/emc/medicine/31475>

Drugs, H., 2022. Topiramate: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 2 February 2022].

https://medlineplus.gov/druginfo/meds/a697012.html>

Dailymed.nlm.nih.gov. 2022. DailyMed - TOPIRAMATE capsule, coated pellets. [online] Available at: < [Accessed 2 February 2022].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=e4886adf-199d-4b19-a4ef-75f8f94cb54e>

Medicines.org.uk. 2022. [online] Available at: < [Accessed 2 February 2022].

https://www.medicines.org.uk/emc/files/pil.1442.pdf>

Accessdata.fda.gov. 2022. [online] Available at: < [Accessed 2 February 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020505s029,020844s024pi.pdf>
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Information on this page was last updated on 15 Feb 2022

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