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Metox Am (5/50 mg) Tablet

Manufactured byWockhardt Ltd.
ContainsAmlodipine (5 mg) + Metoprolol (50 mg)
CURRENTLY UNAVAILABLE

Description

Metox Am (5/50 mg) Tablet is a combination medicine that consists of amlodipine and metoprolol. It is used for the treatment of high blood pressure, abnormal heart rhythms and heart failure. It slows down the activity of your heart and relaxes your blood vessels, allowing your heart to pump blood more easily. This helps to prevent abnormally fast heartbeats and reduces your blood pressure. This medicine is not recommended for use in children below 18 years of age. Metox Am (5/50 mg) Tablet can cause some common side effects like headache, itching, swelling (anywhere on your body), flushing (sense of warmth in the face, ears, neck and trunk), slow heart rate, tiredness, nausea, stomach pain, constipation and feeling of cold in the fingers and toes. Consult your doctor if these side effects become severe. Do not take this medicine if you are allergic to it. This medicine is known to cause temporary headaches in the first week, inform your doctor if this effect persists. Metox Am (5/50 mg) Tablet can make you feel dizzy when you stand up suddenly, so it is advised that you get up slowly from a sitting or lying position. Avoid driving or operating machines as this medicine can cause drowsiness and can affect your mental focus. Metox Am (5/50 mg) Tablet can be taken with or without food. Take this medicine same time every day for the ease of remembering it. Avoid any potassium-rich foods like bananas while taking this medicine. Do not stop taking this medicine without consulting your doctor as abrupt stopping may cause serious conditions like a stroke or a heart attack. Metox Am (5/50 mg) Tablet is not recommended if you have asthma (or any other breathing conditions), kidney or liver conditions. Consult your doctor before taking this medicine if you are pregnant, planning a pregnancy, or are breastfeeding.
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Substitutes

List of substitutes for Metox Am (5/50 mg) Tablet

Side effects

Major & minor side effects for Metox Am (5/50 mg) Tablet

Chest pain and discomfort

Decreased blood pressure

Blurred vision

Dizziness

Shortness of breath

Nausea or vomiting

Skin rash

Swelling of ankles or feet

Redness of face, neck, arms and chest

Muscle pain

Heartburn

Acid or sour stomach

Stomach pain

Anxiety

Diarrhoea

Constipation

Uses of Metox Am (5/50 mg) Tablet

What is it prescribed for?

Hypertension

Metox Am (5/50 mg) Tablet is used in the treatment of high blood pressure (hypertension) that can cause damage to your blood vessels which can lead to heart problems, kidney problems, and other medical conditions.

Ischemic heart disease

Metox Am (5/50 mg) Tablet is used in the treatment of Ischemic heart disease, a serious condition characterized by symptoms such as chest pain, lightheadedness, shortness of breath, irregular heart rate which untreated may lead to severe heart complications.
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?

    Metox Am (5/50 mg) Tablet effects can be observed within 1 hour after taking it.

  • How long do the effects of this medicine last?

    This effects of Metox Am (5/50 mg) Tablet last for an average duration of 24 hours.

  • Is it safe to consume alcohol while taking this medicine?

    Consumption of alcohol is not recommended during treatment with Metox Am (5/50 mg) Tablet due to the risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting.

  • Is this a habit forming medicine?

    No habit forming tendency has been reported for Metox Am (5/50 mg) Tablet.

  • Can this medicine be taken during pregnancy?

    Metox Am (5/50 mg) Tablet is not recommended to be used in pregnancy. Consult your doctor before using this medicine.

  • Can this medicine be taken while breast-feeding?

    Metox Am (5/50 mg) Tablet is not recommended to be used during breastfeeding unless absolutely necessary. All the risks and benefits should be discussed with your doctor before taking this medicine.

Allergy

Avoid using Metox Am (5/50 mg) Tablet if you are allergic to it or other inactive ingredients present in the formulation. Seek immediate medical help if you experience moderate to severe allergic reactions like redness, abnormal swelling (of face/lip or throat), hives, breathing difficulty, etc.

Heart diseases

Metox Am (5/50 mg) Tablet is not recommended if you have heart problems such as a heart block greater than first degree (the electrical signal that controls your heartbeat is partially or completely blocked), cardiogenic shock (where your heart suddenly stops pumping enough oxygen-rich blood to your body), sick sinus syndrome (without a permanent pacemaker in place), sinus bradycardia (slow heart rate), etc., as it may worsen your condition.

Peripheral arterial disease

Metox Am (5/50 mg) Tablet is not recommended for you if you have blood circulation disorders like a peripheral arterial disease as it may worsen your condition.

Warnings for special population

Pregnancy

Metox Am (5/50 mg) Tablet is not recommended to be used in pregnancy. Consult your doctor before using this medicine.

Breast-feeding

Metox Am (5/50 mg) Tablet is not recommended to be used during breastfeeding unless absolutely necessary. All the risks and benefits should be discussed with your doctor before taking this medicine.

General warnings

Heart failure

Metox Am (5/50 mg) Tablet should be used with caution if you have any heart disease due to the increased risk of heart failure. Your doctor may monitor your heart function closely during the treatment with this medicine. Based on your clinical condition your doctor may adjust the dose of this medicine or may prescribe a suitable alternative.

Abrupt withdrawal

Do not stop using Metox Am (5/50 mg) Tablet abruptly without consulting your doctor as it may cause withdrawal symptoms. The dose of this medicine should be reduced gradually over a period of 1 to 2 weeks before withdrawing therapy.

Major surgery

Metox Am (5/50 mg) Tablet should be used with extreme caution if you are undergoing any major surgery due to the increased risk of severe undesirable effects.

Pheochromocytoma

Metox Am (5/50 mg) Tablet should be avoided if you have a tumour called a pheochromocytoma due to the increased risk of worsening your condition. Your doctor may advise a suitable alternative based on your condition.

Lung diseases

Metox Am (5/50 mg) Tablet is not recommended for use if you have lung diseases such as bronchial asthma, bronchospasm, or chronic obstructive pulmonary disease as it may worsen your condition. Your doctor may advise a suitable alternative based on your condition.

Hyperthyroidism

Use Metox Am (5/50 mg) Tablet with caution if you have hyperthyroidism (high thyroid levels) as it may mask some of your symptoms. Report any unusual symptoms to the doctor immediately. Your doctor may monitor your thyroid levels during the treatment with this medicine. Replacement with a suitable alternative may be required based on your clinical condition.

Peripheral vascular diseases

Use Metox Am (5/50 mg) Tablet with caution if you have peripheral vascular diseases (blood vessel disorders) as it may worsen your condition. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be required in some cases based on your clinical condition.

Other medicines

Metox Am (5/50 mg) Tablet may interact with many other medicines and may cause serious undesirable effects. It is advised that you report to the doctor of all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Sports

Athletes are advised to avoid participating in high-risk sports such as archery, racing, shooting, etc. during treatment with Metox Am (5/50 mg) Tablet. Sportspersons should refer to the list of medicines published by the World Anti-Doping Agency to get information about the prohibited substances.

Aortic stenosis

Aortic stenosis is the narrowing of the valve in the large blood vessel branching off the heart (aorta). Use Metox Am (5/50 mg) Tablet with extreme caution in patients suffering from aortic stenosis due to the increased risk of very low blood pressure. Your doctor may monitor your heart function during the treatment. Appropriate dose adjustments or replacement with a suitable alternative may be advised by your doctor based on the clinical condition.

Pediatric use

Metox Am (5/50 mg) Tablet is not recommended for use in children below 18 years of age because the safety and efficacy data is not available.

Driving and operating machines

Metox Am (5/50 mg) Tablet may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating a machine if you experience any of these symptoms after taking this medicine.

Missed Dose

If you forget to take a dose of Metox Am (5/50 mg) Tablet, take it as soon as you remember. If the next dose timing is near, skip the missed dose. Take your next dose at its time. Do not double your dose to compensate for a missed one.

Overdose

Never take more than the prescribed dose. If you suspect that you might have taken an overdose of Metox Am (5/50 mg) Tablet, inform your doctor and seek immediate medical help.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Metox Am (5/50 mg) Tablet due to the risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting.

Interaction with Medicine

Carbamazepine

Diltiazem

Itraconazole

Corticosteroids

Rifampicin

Aminophylline

Ergotamine

Disease interactions

Lung disease

Metox Am (5/50 mg) Tablet is not recommended for use if you have lung problems or any respiratory disorder as it may worsen your condition. Your doctor may prescribe a suitable alternative or adjust the dose of this medicine if required based on your clinical condition.

Heart block

Metox Am (5/50 mg) Tablet is not recommended for use if you have a heart condition known as 'heart block' (the electrical signal that controls your heartbeat is partially or completely blocked) that is greater than the first degree as it may worsen your condition. Your doctor may prescribe a suitable alternative or adjust the dose of this medicine if required based on your clinical condition.

Diabetes

Metox Am (5/50 mg) Tablet should be used with caution if you are diabetic due to the increased risk of low blood sugar levels (hypoglycemia). Your doctor may monitor your blood sugar levels closely during the treatment with this medicine. The dose of this medicine may be adjusted by your doctor based on your clinical condition.

Liver disease

Metox Am (5/50 mg) Tablet should be used with caution if you have liver problems due to the increased risk of serious side effects. Your doctor may monitor your liver functioning closely during the treatment with this medicine. The dose of this medicine may be adjusted by your doctor based on your clinical condition.

Glaucoma

Metox Am (5/50 mg) Tablet should be used with caution if you have glaucoma (a group of eye conditions that damage the optic nerve). A change in the dose of the current glaucoma medicine may be required in some cases. Your doctor may advise an alternative medicine based on your condition.

Hyperlipidaemia

Metox Am (5/50 mg) Tablet should be used with caution if you have hyperlipidemia (high blood cholesterol levels) due to the increased risk of worsening your condition. Your doctor may closely monitor your cholesterol levels, advise an appropriate dose of this medicine, or replace it with a suitable alternative based on your clinical condition.

Cardiogenic shock

Metox Am (5/50 mg) Tablet is not recommended for use if you suffer from cardiogenic shock (a life-threatening condition where your heart suddenly stops pumping enough oxygen-rich blood to your body) as it may worsen your condition.

Food interactions

Do not take Metox Am (5/50 mg) Tablet with grapefruit juice due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Coadministration of multivitamins with minerals and Metox Am (5/50 mg) Tablet may decrease the effects of this medicine. Your doctor may advise you to maintain an appropriate time gap between the consumption of multivitamins with minerals and this medicine to minimize the chances of interaction.

Lab interactions

Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Metox Am (5/50 mg) Tablet as advised by your doctor. It can be taken with or without food. Do not take more or fewer doses than prescribed. Consult your doctor if you experience any undesirable side effects or if you experience headaches after the first week. Do not stop the use of this medicine without consulting your doctor. Do not take any potassium-rich foods like bananas while using Metox Am (5/50 mg) Tablet. Keep away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.

Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works

Amlodipine relaxes your heart muscles and blood vessels. Metoprolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of the blood. Therefore, this combination is effective in reducing blood pressure and strain on the heart.

Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Cardioselective beta blockers, Antihypertensive combinations

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - AMLODIPINE- amlodipine besylate tablet. [online] Available at: < [Accessed 13 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=b52e2905-f906-4c46-bb24-2c7754c5d75b>

Medicines.org.uk. 2021. Amlodipine 10 mg tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 13 September 2021].

https://www.medicines.org.uk/emc/medicine/24889>

Dailymed.nlm.nih.gov. 2021. DailyMed - METOPROLOL TARTRATE tablet, film coatedMETOPROLOL TARTRATE- metoprolol tartrate tablet, film coated. [online] Available at: < [Accessed 13 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=011ee828-5c2a-49b9-bf8e-07f5eb5fc635>

Drugs, H., 2021. Metoprolol: Medlineplus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 13 September 2021].

https://medlineplus.gov/druginfo/meds/a682864.html>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 13 September 2021].

https://www.medicines.org.uk/emc/files/pil.5345.pdf>

Pubchem.ncbi.nlm.nih.gov. 2021. Metoprolol. [online] Available at: < [Accessed 13 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Metoprolol>

Medicines.org.uk. 2021. Amlodipine 5 mg Tablet - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 13 September 2021].

https://www.medicines.org.uk/emc/product/2125>

Pubchem.ncbi.nlm.nih.gov. 2021. Amlodipine. [online] Available at: < [Accessed 13 September 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/2162>

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Information on this page was last updated on 16 Sep 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.