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Nitroplus 50 MG Injection

Manufactured byNeon Laboratories Ltd.
Description
Nitroplus 50 MG Injection is used to manage angina attacks (sudden pains in your chest). It is used after a heart attack (blocked blood flow to your heart), where the pain is not relieved by oral medicines. Nitroplus 50 MG Injection is also used to control blood pressure and to enhance blood flow to your heart during and after heart surgery. This medicine relaxes your blood vessels and helps more blood and oxygen to reach your heart. Nitroplus 50 MG Injection shows side effects like headache, irregular heartbeat, dizziness, weakness, etc. Inform your doctor if these side effects persist for a long time or worsen. Nitroplus 50 MG Injection is given in a hospital under the supervision of a healthcare professional. It is given as an intravenous (into a vein) injection. Your blood pressure will be carefully monitored when this medication is being given. Nitroplus 50 MG Injection may possibly interact with other medicines. Inform your doctor about any other health issues you have or if you are undergoing any medical treatment before receiving this injection. Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or are breastfeeding.

Substitutes

List of substitutes for Nitroplus 50 MG Injection

Nitroject 50 MG Injection
Sun Pharma Laboratories Ltd.

Side effects

Major & minor side effects for Nitroplus 50 MG Injection

  • Headache
  • Irregular heartbeat
  • Dizziness
  • Weakness
  • Vomiting
  • Heartburn
  • Sleepiness

Uses of Nitroplus 50 MG Injection

What is it prescribed for?

  • Angina pectoris
  • Hypertension during surgeries
  • Heart attack
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Nitroplus 50 MG Injection can be seen very quickly. You may start to feel better immediately after the medicine is given.
  • How long do the effects of this medicine last?
    Duration of action of Nitroplus 50 MG Injection is 3 to 4 minutes.
  • Is it safe to consume alcohol while taking this medicine?
    Do not consume alcohol if you are on treatment with Nitroplus 50 MG Injection. Alcohol may increase the risk of side effects like dizziness, drowsiness, difficulty concentrating, breathing difficulties, etc.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported for Nitroplus 50 MG Injection.
  • Can this medicine be taken during pregnancy?
    Nitroplus 50 MG Injection contains alcohol (ethanol). Consult your doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    Nitroplus 50 MG Injection contains ethanol, which may pass into your breast milk. If you are breastfeeding, inform your doctor beforehand.

Allergy

Avoid taking Nitroplus 50 MG Injection if you are allergic to it. Contact your doctor immediately if you experience symptoms like rashes, itching/swelling (particularly of the face/tongue/throat), severe dizziness, and breathing difficulty.

Anaemia

Anaemia is a condition in which your blood does not have enough healthy red blood cells. Avoid Nitroplus 50 MG Injection if you are anaemic or have low levels of haemoglobin (blood cells that carry oxygen throughout your body). Large doses of this medicine may worsen your condition.

Glaucoma

Glaucoma is a group of eye conditions that damage the optic nerve (a nerve responsible for good vision). It is caused by abnormally high pressure in your eyeball which can also lead to blindness. Glaucoma often has no symptoms other than gradual loss of vision. Nitroplus 50 MG Injection is not recommended for use if you have glaucoma as this medicine may also increase pressure inside your eyes. This can potentially lead to blindness.

Increased intracranial pressure

Intracranial pressure (ICP) is the pressure exerted by fluids such as cerebrospinal fluid (CSF) inside your skull and on the brain tissue. Nitroplus 50 MG Injection is not recommended if you have a condition where the intracranial pressure is elevated, as this medicine may worsen your condition.

Medicine for erectile dysfunction

Erectile dysfunction occurs when a man can not get or keep an erection firm enough for sexual intercourse. Nitroplus 50 MG Injection is not recommended for use if you are taking medicines for the treatment of erectile dysfunction.

Pericarditis

Pericarditis is a swelling and irritation in the pericardium (the thin, sac-like membrane that surrounds your heart). Nitroplus 50 MG Injection is not recommended if you have pericarditis. This medicine may lower your cardiac output (the amount of blood your heart pumps each minute) which can further worsen your condition.
Warnings for special population

Pregnancy

Nitroplus 50 MG Injection contains alcohol (ethanol). Consult your doctor before taking this medicine.

Breast-feeding

Nitroplus 50 MG Injection contains ethanol, which may pass into your breast milk. If you are breastfeeding, inform your doctor beforehand.
General warnings

Other diseases

If you have or have had any other troubles of heart, lung, thyroid, kidney, liver etc., then inform your doctor before taking Nitroplus 50 MG Injection as this medicine can interact with the existing disease and worsen your condition.

Driving or using heavy machinery

Nitroplus 50 MG Injection contains some amount of alcohol (ethanol). This can make you drowsy and affect your ability to concentrate. Hence, do not drive or do anything that requires mental attention.

Methemoglobinemia

Methemoglobinemia (MetHb) is a blood disorder in which an abnormal amount of methemoglobin is produced. Methemoglobin is a form of haemoglobin that carries oxygen throughout your body. Nitroplus 50 MG Injection can lead to the development of methemoglobinemia. Inform your doctor if you experience symptoms like blue-coloured skin, headache, fatigue, lack of energy, etc.

Malnutrition

Nitroplus 50 MG Injection should be avoided if you are malnourished (lack of sufficient nutrients in your body).

Missed Dose

Nitroplus 50 MG Injection is given in the hospital setting by a qualified healthcare professional, thus the chances of missing a dose are very less. If you miss an appointment for a dose of this medicine, contact your doctor immediately and schedule the dose as soon as possible.

Overdose

As Nitroplus 50 MG Injection is given in a hospital setting by a qualified healthcare professional, the possibility of an overdose is quite low. If an overdose is suspected, the doctor will initiate emergency medical treatment.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Do not consume alcohol if you are on treatment with Nitroplus 50 MG Injection. Alcohol may increase the risk of side effects like dizziness, drowsiness, difficulty concentrating, breathing difficulties, etc.
Interaction with Medicine

Prilocaine

Riociguat

Dihydroergotamine

Amitriptyline

Sildenafil

Amlodipine

Disease interactions

Hypotension

Nitroplus 50 MG Injection should be used with extreme caution if you have low blood pressure (<90 mm Hg). This medication may further lower your blood pressure and can worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Nitroplus 50 MG Injection is normally given by a qualified healthcare professional in a clinic or hospital. You might feel some pain at the site of injection that usually goes away soon. You will be closely monitored for at least 30 minutes after receiving the injection for signs of allergic reactions like redness, swelling, breathing difficulties etc. It can cause headaches, but they generally go away after a few days of therapy. Consult your doctor if the problem persists.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Nitroplus 50 MG Injection is a vasodilator (a medicine that widens your blood vessels). It relaxes your blood vessels and helps in controlling blood pressure. It also lowers the amount of oxygen required by your heart. Thus, it reduces the workload on your heart and prevents attacks of angina (chest pain).
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antianginal agents, Vasodilators

Schedule

Schedule H

Medicines.org.uk. 2021. [online] Available at: < [Accessed 19 August 2021].

https://www.medicines.org.uk/emc/files/pil.3792.pdf>

DailDailymed.nlm.nih.gov. 2021. DailyMed - NITROGLYCERIN IN DEXTROSE- nitroglycerin injection. [online] Available at: < [Accessed 19 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=457a026c-ebce-4701-9deb-2d7652759a99>

Pubchem.ncbi.nlm.nih.gov. 2021. Nitroglycerin. [online] Available at: < [Accessed 1 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/4510#section=Top>
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Information on this page was last updated on 26 Aug 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.